Publications by authors named "Lian-sen Wang"

Article Synopsis
  • - The study examined hand, foot, and mouth disease (HFMD) in Linyi, Shandong Province, China from 2007 to 2012, using data from the National Notifiable Disease Reporting System (NNDRS) and genetic analysis of enterovirus A71 (EV-A71).
  • - HFMD cases peaked annually from April to July, particularly in May, with the highest reported incidence and mortality occurring in 2009 (14,697 cases, 9 deaths).
  • - Most affected patients were children under 3, with EV-A71 and coxsackievirus A16 both circulating as primary causes of the disease; all isolated EV-A71 strains belonged to the C4a evolutionary branch
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Objective: To understand the clinical features of death from hand, foot and mouth disease (HFMD) and to explore the early warning index of HFMD death.

Methods: A total of 41 HFMD death cases were collected as case group in Shandong province between 2009 and 2011, and another 123 serious HFMD cases were selected as control group according to the similar gender, place of origin and hospital level, with the ratio at 1:3. We investigated the general situation, clinical treatment, past medical history, clinical symptoms and signs of the ill children, and applied the conditional logistic regression to explore early warning index of HFMD death.

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