Publications by authors named "Lian-hua Wei"

Article Synopsis
  • Diagnostic panels that use multiple biomarkers are better for diagnosing hepatocellular carcinoma (HCC) compared to single biomarkers, with models like ASAP and GALAD being evaluated for effectiveness.
  • In a study involving patients with chronic liver diseases (CLDs) from 14 hospitals in China, the ASAP model showed superior performance in detecting HCC compared to the GALAD model and individual biomarkers.
  • The ASAP model was particularly effective in identifying HCC across various types of CLDs and excelled in early-stage HCC detection, despite using one fewer biomarker than the GALAD model.
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Background: The incidence and mortality of liver cancer are among the highest of all malignant tumors in China. The high recurrence rate after conventional hepatectomy is worrying. There is a lack of effective prognostic indicators for liver cancer.

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Backgruound: The common reference intervals (RIs) for thyroid hormones currently used in China are provided by equipment manufacturers. This study aimed to establish thyroid hormone RIs in the population of Lanzhou, a city in the subplateau region of northwest China, and compare them with previous reports and manufacturer-provided values.

Methods: In total, 3,123 individuals (1,680 men, 1,443 women) from Lanzhou, an iodine-adequate area of China, perceived as healthy were selected.

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BACKGROUND Polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are reportedly associated with myocardial infarction (MI) risk. However, definitive evidence of this association is lacking. In this study, we investigated the potential association of eNOS gene polymorphisms with MI risk by conducting a meta-analysis of studies evaluating this association.

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Objective: To study the distribution and drug resistance of methicillin resistant Staphylococcus strains in various specimens of inpatients in burn wards, and to provide reference for clinical treatment.

Methods: Bacteria were isolated from specimens of wound exudate, blood, sputum, and bronchoalveolar lavage fluid etc., which were collected from patients hospitalized in our burn wards from January 2008 to December 2010.

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Objective: To investigate the drug-resistance of Acinetobacter baumannii (Ab) isolated from patients in burn ward, and study the incidence of 16S rRNA methylase genes mediated high-level aminoglycoside drug-resistance and its mechanism of transfer.

Methods: A total of 40 Ab clinical isolates were collected from burn ward in Gansu Province People's Hospital from May 2006 to Dec. 2007.

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Objective: To investigate the relationship among antibiotic resistance, integron, homology of multi-drug resistant Acinetobacter Baumannii isolated from burn ward.

Methods: Thirty-one strains of multi-drug resistant Acinetobacter baumannii were isolated from samples of burn wound exudate in hospitalized patients of Gansu Province People's Hospital. The minimum inhibitory concentrations (MIC) of these strains against 11 antibiotics was examined by agar dilution method.

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Objective: To study the infectious strains of bacteria in our burn ward in recent 5 years, and analyze their antibiotic resistance.

Methods: Bacteria were isolated from the wound excretions of 306 burn patients hospitalized during 2001 to 2006 for analyzing their strains and their antibiotic resistance.

Results: 378 strains were Grams positive bacteria, among them Staphylococcus aureus was the predominant strain.

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Objective: To investigate the distribution and drug resistance of acinetobacter isolated from burn wounds.

Methods: The acinetobacter strains were isolated and identified by routine methods. Based on the recommendation of NCCLS, AmpC enzyme was determined by cefoxiti three-dimensional test, ESBLs by disk diffusion method and bacterial susceptibility by Kirby-Bauer agar diffusion method.

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