Carbon quantum dots as a fluorophore for "inner filter effect" detection of metronidazole in pharmaceutical preparations.

With houttuynia cordata as carbon source, photoluminescent carbon quantum dots (CDs) were obtained a one-step hydrothermal procedure. The absorption band of metronidazole (MNZ, maximum absorption wavelength at 319 nm) can well overlap with the excitation bands of CDs (maximum excitation wavelength at 320 nm). A fluorescent approach has been developed for detection of MNZ based on the inner filter effect (IFE), in which as-prepared CDs act as an IFE fluorophore and the MNZ as an IFE absorber.

A Polyol-Mediated Fluoride Ions Slow-Releasing Strategy for the Phase-Controlled Synthesis of Photofunctional Mesocrystals.

There are only a few inorganic compounds that have evoked as much interest as sodium yttrium fluoride (NaYF₄). Its extensive applications in various fields, including transparent displays, luminescence coding, data storage, as well as biological imaging, demand the precise tuning of the crystal phase. Controlling the emergence of the desired α-phase has so far remained a formidable challenge, especially via a simple procedure.

Preparation of polymethacrylate monolith modified with cysteine for the determination of Cr(iii) ions.

In this study, a simple and rapid polymer monolith microextraction procedure was developed for the determination of Cr(iii) ions by inductively coupled plasma-atomic emission spectrometry. A monolithic column modified with cysteine was synthesized and characterized by scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray photoelectron spectroscopy, thermal gravimetric analysis, specific surface area analysis and pore size distribution analysis. The influences of analytical parameters such as sample pH, adsorption time, eluent type, and coexisting ions were examined.

Study of human dopamine sulfotransferases based on gene expression programming.

A quantitative model is developed to predict the Km of 47 human dopamine sulfotransferases by gene expression programming. Each kind of compound is represented by several calculated structural descriptors of moment of inertia A, average electrophilic reactivity index for a C atom, relative number of triple bonds, RNCG relative negative charge, HA-dependent HDSA-1, and HBCA H-bonding charged surface area. Eight fitness functions of the gene expression programming method are used to find the best nonlinear model.

Simple and sensitive spectrofluorometric method for the determination of protein using an europium-thenoyltrifluoroacetone probe.

The fluorescence intensity of the europium (Eu3+)-thenoyltrifluoroacetone (TTA) complex can be remarkably enhanced by human serum albumin (HSA) in a Britton-Robinson buffer solution. Based on this fact, a simple, rapid, and sensitive method has been developed for the determination of proteins at the nanogram level by fluorescence spectroscopy. Under the optimum conditions, the enhanced fluorescence intensity is proportional to the concentration of HSA.

Predicting the activity of drugs for a group of imidazopyridine anticoccidial compounds.

Gene expression programming (GEP) is a novel machine learning technique. The GEP is used to build nonlinear quantitative structure-activity relationship model for the prediction of the IC(50) for the imidazopyridine anticoccidial compounds. This model is based on descriptors which are calculated from the molecular structure.

Determination of silver ion with cadmium sulfide quantum dots modified by bismuthiol II as fluorescence probe.

CdS quantum dots (QDs) modified with bismuthiol II potassium salt is prepared in one step. Based on the characteristic fluorescence enhancement of CdS QDs at 480 nm by silver ions, simultaneously, a red shift of fluorescence emission bands of CdS QDs from 460 to 480 nm is observed. A simple, rapid, sensitive and specific detection method for silver ion is proposed.

Analysis of eupatilin-human serum albumin interactions by means of spectroscopic and computational modelling.

The interaction of eupatilin (5,7-dihydroxy-3',4',6-trimethoxyflavone) with human serum albumin (HSA) was studied at simulative physiological pH, with a HSA concentration of 3.0 x 10(-6)mol L(-1) and eupatilin concentrations over the range of 6.0 x 10(-6) to 1.

Synthesis and efficiency of a chelating fiber for preconcentration and separation of trace Au(III) and Pd(IV) from solution samples.

A novel poly(acryl-benzoylamidrazone-acryl-benzoylhydrazine) chelating fiber was synthesized simply from nitrilon (polyacrylonitrile fiber). The structure of the chelating fiber was verified with the help of FT-IR spectrum. The parameters influencing the efficiency of the fiber for concentrating trace amounts of Au(III) and Pd(IV) were investigated in detail.

[Flow injection analysis of ciprofloxacin by terbium sensitized chemiluminescence method].

A new flow injection chemiluminescence (CL) method for the determination of Ciprofloxacin (CPLX) was described. The method was based on the weak CL reaction of Ce(IV)-SO3(2-) sensitized by Tb3+ -CPLX. The relative CL intensity was linear with the concentration of CPLX in the range of 9.

[Effect of components of dang-gui-bu-xue decoction on hematopenia].

Objective: To investigate the effects and the related mechanisms of the components of Dang-Gui-Bu-Xue decoction (DGBXD) on improving blood deficiency.

Method: The effects of promoting hematopoietic function were observed with the blood difficient model mice, by giving components of DGBXD. RBC, WBC, reticulocytes and bone marrow nucleated cells (BMNC) were determined.