Genomic analysis of early ST32 Acinetobacter baumannii strains recovered in US military treatment facilities reveals distinct lineages and links to the origins of the Tn6168 ampC transposon.

Objectives: To study the population structure and genomic characteristics, including antimicrobial resistance genes, plasmid types and surface polysaccharide type, of the globally distributed Acinetobacter baumannii belonging to ST32 (Institut Pasteur scheme).

Methods: Antibiotic resistance phenotype for 19 antibiotics was determined using Vitek 2. Whole-genome sequencing was performed using the Illumina MiSeq platform.

Transposons Carrying the Aminoglycoside and Beta-Lactam Resistance Genes in .

This study examines the genetic contexts and evolutionary steps responsible for the formation of the widely spread transposon Tn carrying and which confers resistance to beta-lactam and aminoglycoside antibiotics in Gram-negative bacteria. The and genes were found in several transposons. They were first observed within an IS bounded 3.

Genomic analysis of diverse environmental isolates identifies plasmids, antibiotic resistance genes, and capsular polysaccharides shared with clinical strains.

an important pathogen known for its widespread antibiotic resistance, has been the focus of extensive research within its genus, primarily involving clinical isolates. Consequently, data on environmental and other species remain limited. Here, we utilized Illumina and Nanopore sequencing to analyze the genomes of 10 isolates representing 6 different species sourced from aquatic environments in South Australia.

The evolutionary tale of eight novel plasmids in a colistin-resistant environmental isolate.

is an important opportunistic pathogen known for its high levels of resistance to many antibiotics, particularly those considered last resorts such as colistin and carbapenems. Plasmids of this organism are increasingly associated with the spread of clinically important antibiotic resistance genes. Although is a ubiquitous organism, to date, most of the focus has been on studying strains recovered from clinical samples ignoring those isolated in the environment (soil, water, food, etc.

Medium-term outcomes of idiopathic ventricular fibrillation survivors and family screening: a multicentre experience.

Aims: Early repolarization (ER) has been linked to poorer outcomes in idiopathic ventricular fibrillation (IVF). The role of family screening in IVF is not clear. Our aim was to review predictors for poorer outcomes and evaluate the role of family screening in IVF.