Delabeling, safety, and impact of β-lactam allergy testing: A systematic review.

Background: To improve β-lactam delabeling outcomes, we need to understand current practice and the evidence base regarding its outcomes, safety, and impact.

Objectives: We sought to assess the existing published evidence reporting on the effectiveness of penicillin allergy testing and delabeling.

Methods: We conducted a systematic review of studies reporting β-lactam delabeling practices and outcomes after testing, including β-lactam use and patient understanding of the delabeling result.