Publications by authors named "Lia Sisuashvili"
Intussusception in adults is rare and poses a diagnostic challenge, often due to neoplastic causes. Metastatic melanoma is known to spread to the gastrointestinal tract, especially the small intestine. We report the case of a patient with obstructive symptoms and a history of metastatic melanoma.
View Article and Find Full Text PDFBackground: Female recipients of allogeneic hematopoietic stem cell transplantation are at high risk of developing human papillomavirus (HPV)-associated lesions and (pre)cancer. We describe the results of a cervical cancer screening program in these women.
Methods: From 2010 to 2022, 70 female recipients of allogeneic hematopoietic stem cell transplantation in our institution entered a standardized protocol of gynecological evaluation.
Article Synopsis
- Perinatal mortality is notably high in low- and middle-income countries, with accurate fetal gestational age assessment essential for differentiating between prematurity and intrauterine growth restriction for better management strategies.
- The study conducted in Barcelona sought to validate post-mortem ultrasound measurements of the cerebellum as a method for estimating gestational age in cases of fetal and perinatal deaths.
- Findings demonstrated a strong correlation between various cerebellar measurements and gestational age, with the extrauterine transcerebellar diameter emerging as the most reliable predictor, regardless of the trimester in which the measurement was taken.
Article Synopsis
- Scientists don't know much about vulvar squamous cell carcinoma (VSCC), a cancer mostly found in older women, especially about its mutations and how different types affect survival.
- In a study of 60 patients, they found three main types of VSCC related to the human papillomavirus (HPV) and some common gene mutations, particularly in the TP53 gene.
- Patients with mutations in TP53 and CCND1 had a much higher chance of their cancer coming back, suggesting that these changes could help doctors find better treatments for VSCC.
Article Synopsis
- - Penile squamous cell carcinoma (PSCC) is divided into two main types: HPV-associated and HPV-independent, with the prognosis being influenced by the status of the p53 protein, which is somewhat debated.
- - A study involving 122 PSCC patients explored the correlation between HPV and p53 status, categorizing tumors into three subtypes based on immunohistochemistry and HPV tests.
- - Results showed that patients with HPV-independent tumors and abnormal p53 patterns had significantly worse outcomes, with a higher rate of disease-related deaths compared to those with HPV-associated or HPV-independent/p53-normal tumors.