Control efficacy of Bt-Cry1Ab maize (event DBN9936) against Ostrinia furnacalis (Guenée) in Sichuan Province, China.

Background: The Asian corn borer (ACB), Ostrinia furnacalis (Guenée), is a major pest restricting maize production in Asia. The Chinese government has approved the commercial planting of Bt-Cry1Ab maize (event DBN9936), but its control potential against the ACB in southern regions remains unclear. This study evaluated the sensitivity of ACB to Cry1Ab protein expressed in Bt-Cry1Ab maize and determined the control efficacy of Bt-Cry1Ab maize against the ACB in Sichuan Province, a major maize-producing region in southern China, based on pilot planting in the field, and larval feeding bioassays in the field and laboratory.

Synergistic effect of venetoclax and ibrutinib on ibrutinib-resistant ABC-type DLBCL cells.

Despite the widespread use of R-CHOP therapy in diffuse large B-cell lymphoma (DLBCL), the therapeutic efficacy for this disease remains suboptimal, primarily due to the heterogeneity of refractory and/or relapsed diseases. To address this challenge, optimization of DLBCL treatment regimens has focused on the strategy of combining an additional drug "X" with R-CHOP to enhance efficacy. However, the failure of R-CHOP combined with the BTK inhibitor ibrutinib in treating ABC-type DLBCL patients has raised significant concerns regarding ibrutinib resistance.

Cell Penetrating Peptide Enhances the Aphidicidal Activity of Spider Venom-Derived Neurotoxin.

HxTx-Hv1h, a neurotoxic peptide derived from spider venom, has been developed for use in commercial biopesticide formulations. Cell Penetrating Peptides (CPPs) are short peptides that facilitate the translocation of various biomolecules across cellular membranes. Here, we evaluated the aphidicidal efficacy of a conjugated peptide, HxTx-Hv1h/CPP-1838, created by fusing HxTx-Hv1h with CPP-1838.

Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test.

Objective: To study the effects of chemotherapy on cognitive function in breast cancer patients, and to investigate the relationship of MemTrax test of memory and related functions to the FACT-Cog functional self-assessment for the evaluation and management of chemobrain.

Methods: In this prospective cohort study, clinical information of pathologically confirmed female breast cancer patients who decided to receive chemotherapy were collected in a questionnaire which was developed for this study and provided as a supplementary file. The FACT-Cog self-assessment and MemTrax test were administered before and after the chemotherapy treatments.

SFXN3 is a Prognostic Marker and Promotes the Growth of Acute Myeloid Leukemia.

Acute myeloid leukemia (AML) is a heterogeneous disease with rapid progression and frequent mutations. Sideroflexin3 (SFXN3) has been shown to be involved in various neurodegenerative diseases. However, the role of SFXN3 in AML remains unclear.

Clinical application of the modified neck-shoulder technique based on membrane autopsy to laparoscopic totally extraperitoneal prosthesis for indirect inguinal hernia.

Objective: To investigate the anatomical basis and clinical application value of the modified neck-shoulder technique based on membrane autopsy in laparoscopic totally extraperitoneal prosthesis (TEP) for tension-free repairs of indirect inguinal hernia.

Methods: In this retrospective cohort study, we analyzed the clinical data of 136 patients with indirect inguinal hernia who underwent laparoscopic TEP for tension-free repairs at the Department of Gastroenterological Surgery Unit 1, the First Hospital of Putian City, Fujian Province from June 2017 to June 2020. The patients were divided into the modified neck-shoulder technique group (68 cases) and the traditional surgery group (68 cases), according to the different surgical methods.

A dye-quenched/sensitized switching upconversion nanoprobe for high-contrast mapping of the pH-related tumor microenvironment.

Nanoprobes based on lanthanide-doped upconversion nanoparticles (UCNPs) exhibit promising potential in bioimaging and biosensing due to their unique optical properties. However, conventional UCNP nanoprobes based on the dye quenching effect are still limited in biosensing due to their low upconversion efficiency. The advent of dye-sensitized upconversion has resulted in nanoprobes with significantly enhanced efficiency; however, these still suffer from a high initial emissive background.

ZIP Genes Are Involved in the Retransfer of Zinc Ions during the Senescence of Zinc-Deficient Rice Leaves.

Rice lacks sufficient amounts of zinc despite its vitality for human health. Leaf senescence enables redistribution of nutrients to other organs, yet Zn retransfer during deficiency is often overlooked. In this hydroponic experiment, we studied the effect of Zn deficiency on rice seedlings, focusing on the fourth leaf under control and deficient conditions.

Large-area field application confirms the effectiveness of toxicant-infused bait for managing Helicoverpa armigera (Hübner) in maize fields.

Background: Maize is one of the world's most important crops, so its stable production and supply is crucial for food security and socioeconomic development. The cotton bollworm, Helicoverpa armigera (Hübner), is one of the major pests in maize. We evaluated the control effect of a bio-bait, an adult attractant, combined with insecticide, a 'toxicant-infused bait', on H.

Case Report: Clinical analysis of a cluster outbreak of pneumonia.

Objective: To explore the clinical characteristics and prognosis of clustered cases of psittacosis pneumonia.

Method: We retrospectively analyzed the clinical data of a cluster outbreak of psittacosis pneumonia. The analysis included epidemiological data, clinical symptoms, laboratory results, and prognosis.

Comparing the impact of comprehensive care with conventional care in children with congenital heart disease: a systematic review and meta-analysis.

Background: This study compares the impact of comprehensive care and conventional care on interventional therapy in children with congenital heart disease and to provide a reference basis for clinical care.

Methods: Clinical randomized controlled trials (RCTs) examining care during interventional therapy in children with congenital heart disease were identified in the PubMed, Web of Science, Embase, China National Knowledge Infrastructure (CNKI), and Wanfang databases using a combination of subject terms and free terms. The retrieval time was from the establishment of the database to November 27th, 2022.

Comprehensive bioinformatics analysis of the expression, prognostic value, and immune infiltration of chromobox family members in cervical cancer.

Objectives: Cervical cancer (CC) is the fourth most prevalent type of cancer in women worldwide and it is considered the leading cause of tumor-related death and malignancy. As part of complexes involved in epigenetic control, the proteins of the chromobox (CBX) family have been found to have a role in the growth of malignancies by preventing differentiation and increasing proliferation. Here, by a thorough investigation, we investigated the expression, prognostic significance, and immune infiltration of CBX in patients with CC.

Deletion of the Loop Linking Two Domains of Exo-Inulinase InuAMN8 Diminished the Enzymatic Thermo-Halo-Alcohol Tolerance.

Inulin is the rich water-soluble storage polysaccharide after starch in nature, and utilization of inulin through hydrolysis of exo-inulinases has attracted much attention. Thermo-halo-alcohol tolerance is essential for exo-inulinase applications, while no report reveals the molecular basis involved in halo-alcohol tolerance of exo-inulinases experimental data. In this study, two loops of exo-inulinase InuAMN8, including the loop built with GHVRLGPQP linking domains of Glyco_hydro_32N and Glyco_hydro_32C and another loop built with GGAG in the catalytic domain, were deleted to generate mutants MutG360Δ9 and MutG169Δ4, respectively.

Nitrogen Application Rate Affects the Accumulation of Carbohydrates in Functional Leaves and Grains to Improve Grain Filling and Reduce the Occurrence of Chalkiness.

Chalkiness, which is highly affected by nitrogen (N) management during grain filling, is critical in determining rice appearance quality and consumer acceptability. We investigated the effects of N application rates 75 (N), 150 (N), and 225 (N) kg ha on the source-sink carbohydrate accumulation and grain filling characteristics of two hybrid rice cultivars with different chalkiness levels in 2019 and 2020. We further explored the relationship between grain filling and formation of chalkiness in superior and inferior grains.

[Prenatal screening and diagnosis for a fetus with mosaic sex chromosome abnormality].

Objective: To carry out prenatal screening and diagnosis for a woman with advanced maternal age.

Methods: Non-invasive prenatal testing (NIPT) was carried out to determine the risk of fetal chromosome aneuploidy. Aminiocentesis was proceeded for fetal chromosomal karyotyping and copy number variation sequencing (CNV-seq).

Population Fitness of Fabricius (Diptera: Syrphidae) Feeding on Different Species of Aphids.

Fabricius, as one of the most common beneficial predatory insects in agricultural ecosystems, provides pollination and biological control services that help improve crop yield and maintain biodiversity. However, systematic research is needed on the species of aphids used for propagation. To develop highly fit populations of the important insect predator and crop pollinator, , for research and commercial use, further research is needed to develop the most nutritious diet and efficient propagation methods.

Host plants and pollination regions for the long-distance migratory noctuid moth, Hufnagel in China.

Nocturnal moths are important pollinators of plants. The clover cutworm, , is a long-distance migratory nocturnal moth. Although the larvae of .

Effects of X-ray irradiation on the fitness of the established invasive pest fall armyworm Spodoptera frugiperda.

Background: Spodoptera frugiperda has spread to Africa, Asia, and Oceania, posing a serious threat to global agriculture. We estimated the appropriate dose of X-ray sterilization for S. frugiperda using an X-ray irradiation instrument to investigate environmentally acceptable control techniques, laying the framework for future applications of sterile insect technology (SIT) to manage the pest environmentally-friendly.

Prognostic Value of a Ferroptosis-Related Gene Signature in Patients With Head and Neck Squamous Cell Carcinoma.

Ferroptosis is an iron-dependent programmed cell death (PCD) form that plays a crucial role in tumorigenesis and might affect the antitumor effect of radiotherapy and immunotherapy. This study aimed to investigate distinct ferroptosis-related genes, their prognostic value and their relationship with immunotherapy in patients with head and neck squamous cell carcinoma (HNSCC). The differentially expressed ferroptosis-related genes in HNSCC were filtered based on multiple public databases.

lncRNA AABR07005593.1 potentiates PM-induced interleukin-6 expression by targeting MCCC1.

Background: Fine particle pollution, specifically pollution by fine particulate matter (PM), remains a significant concern in developing countries and plays an important role in the development and progression of respiratory diseases. Increasing evidences have demonstrated that long non-coding RNAs (lncRNAs) may act as vital molecules by binding to specific RNA-binding protein (RBP); however, their relationship with PM pollution is largely unexplored.

Objective: We investigated the association between lncRNA and respiratory system inflammation caused by PM.

Population Dynamics and Reproductive Developmental Analysis of Helicoverpa armigera (Lepidoptera: Noctuidae) Trapped Using Food Attractants in the Field.

Monitoring adult populations of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae), a major agricultural pest, provides data useful for its control. Food attractants, considered as adult insect behavior regulators based on the preference of an herbivorous pest for food sources or their volatiles, also have great potential for monitoring populations. To study the feasibility of monitoring the population dynamics and reproductive development of H.

Potential trade-offs between reproduction and migratory flight in Spodoptera frugiperda.

Since 2016, the fall armyworm (FAW, Spodoptera frugiperda) has invaded large parts of Africa and Asia, impacting millions of hectares of maize crops and thereby posing a major threat to food security. The rapid geographic spread and outbreak dynamics of S. frugiperda are tied to its unique dispersal ability and long-distance migration capability.

Ambient Humidity Affects Development, Survival, and Reproduction of the Invasive Fall Armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae), in China.

Ambient humidity can directly affect the water balance in insects. The migratory fall armyworm, Spodoptera frugiperda Smith, has spread to more than 60 countries and regions in Africa, Asia, and Oceania that have a great difference in average ambient humidity. Understanding the effects of ambient humidity changes on its development, survival, and reproduction can help to predict its population dynamics in different habitats.