Publications by authors named "LiLi Hou"

Study Objectives: The Oxidative Balance Score (OBS), which reflects overall oxidation through diet and lifestyle, has been linked to sleep, but few studies have clarified this relationship. We investigated the association between OBS and sleep duration, and whether oxidative stress (OS) and inflammation mediate the underlying mechanisms.

Methods: Data were obtained from the National Health and Nutrition Examination Survey spanning the years 2007 to 2018.

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All-visible light-activated diarylethene (DAE) photoswitches are highly attractive for applications in smart photoresponsive materials. The photocyclization of DAE the low-lying excited triplet state through triplet energy transfer (TET) from a sensitizer has been proven to be an effective approach for the realization of this scheme. However, the TET process is sensitive to oxygen and typically requires more than one sensitizer per photoswitch to facilitate sensitized photocyclization.

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Resolving the separation between two incoherent optical sources with high precision is of great significance for fluorescence imaging and astronomical observations. In this paper, we focus on a more general scenario where two sources have unequal brightnesses. We give the ultimate precision limit with respect to separation by using the quantum Fisher information.

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This study aimed to investigate the benefits of using three-dimensional (3D)-printed hip joint fixators after intra-arterial chemotherapy (IAC) by inguinal femoral artery puncture in children with retinoblastoma. Overall, 79 cases of retinoblastoma who had undergone IAC through the femoral artery were selected and divided into an observation group of 50 cases and an intervention group of 29 cases according to the hemostasis method employed. The patients in the observation group were treated with sandbags for hemostasis, while those in the intervention group were given 3D-printed hip joint fixators to help immobilize the hips and sandbags.

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Aims: Thyroid hormones impact lipid metabolism and glucose homoeostasis through both central and peripheral regulation; however, little research has delved into the association between thyroid hormone sensitivity and metabolically obese phenotypes. We aimed to investigate the correlation between indices of central and peripheral sensitivity to thyroid hormones and metabolically obese phenotypes in euthyroid Chinese adults.

Methods: This cross-sectional study included 20,084 euthyroid individuals.

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Article Synopsis
  • Soil dielectric sensors are essential for measuring real-time soil moisture, but their accuracy is affected by soluble salts in the soil.
  • A study tested eight popular sensors across various salinity levels, finding that most overestimated soil moisture, particularly at higher salinities, while the EC-5 sensor remained accurate.
  • The results suggest that for soil salinity levels greater than 1.0 dS·m, calibrated sensors like TDR series and EC-5 are the best options to ensure accurate soil moisture readings.
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  • Sleep-disordered breathing (SDB) is a prevalent but often overlooked condition in patients with head and neck cancers (HNC), and untreated SDB can have serious health consequences.
  • The study aimed to assess how common SDB is among HNC patients and to evaluate the effectiveness of different assessment methods.
  • Results showed that SDB prevalence ranges from 57-90% before cancer treatment and varies widely after treatment, highlighting the need for consistent diagnostic criteria in future studies.
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Objective: To compare the effects of starting mouth opening exercises at two different times on trismus in postoperative radiotherapy patients with oral cancer.

Methods: Through a prospective randomized controlled trial, purposive sampling was used to select 76 patients undergoing postoperative radiotherapy for oral cancer from March 2023 to January 2024 at the Department of Oral and Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Patients were randomly divided into an experimental group (n = 38) and a control group (n = 38) using a random number table at a ratio of 1:1.

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Aim(s): The study aimed to investigate the current status of physical activity (PA) levels and associated factors among lung cancer survivors who have undergone nonsurgical treatments.

Background: PA has been incorporated as a nonpharmacological intervention in the rehabilitation programmes of cancer patients, playing a crucial role in alleviating symptom burden and enhancing the quality of life among lung cancer survivors. Understanding the potential influencing factors of PA levels aids in formulating targeted intervention strategies.

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Background: Temozolomide (TMZ) is the first-line chemotherapeutic drug for gliomas treatment. However, the clinical efficacy of TMZ in glioma patients was very limited. Therefore, it is urgently needed to discover a novel approach to increase the sensitivity of glioma cells to TMZ.

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  • - A study was conducted with 60 mice over 28 days to evaluate the effects of curcumin on the negative impacts of Deoxynivalenol (DON) and Aflatoxin B1 (AFB1) exposure.
  • - Mice given curcumin showed improved immune response, including higher levels of immunoglobulins (IgA and IgG) and T lymphocytes, along with reduced structural damage to the spleen.
  • - Curcumin also reduced apoptosis in mice by lowering certain enzyme activities and pro-apoptotic markers, indicating its potential to help counteract the immunosuppression caused by the toxins.
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Purpose: To comprehensively analyze the factors associated with different intensities of physical activity and sedentary behavior in newly diagnosed lung cancer patients in the early postoperative period, providing a basis for clinically tailored personalized intervention measures.

Methods: A cross-sectional study design was employed, and 915 patients newly diagnosed with lung cancer completed a questionnaire survey on demographics, disease, health-related fitness, and psychosocial factors. Physical activity levels and sedentary behaviors were assessed using the International Physical Activity Questionnaire.

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  • Breast cancer is the top cause of cancer deaths in women, and radiotherapy is important for reducing recurrence after breast-conserving surgery (BCS).
  • The study compared acute skin reactions in 152 patients receiving either hypofractionated or conventional whole-breast irradiation following BCS, using RTOG criteria to assess skin toxicity.
  • Results showed no significant difference in skin reactions between the two methods, indicating that hypofractionated radiotherapy is just as tolerable and effective as conventional methods, with potential benefits in terms of convenience and cost.
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  • - Chemotherapy combined with immunotherapy shows promise for treating breast cancer, but current treatments with paclitaxel and PD-1/PD-L1 inhibitors have limited effectiveness and side effects, like peripheral neuropathy.
  • - Research identified that the protein Dickkopf-1 (DKK1) is increased after paclitaxel treatment, negatively affecting T cell activity and limiting the drug's antitumor effects.
  • - Using an anti-DKK1 antibody alongside paclitaxel improved cancer treatment outcomes and reduced neuropathy symptoms in mouse models, suggesting a new approach for safer breast cancer therapies.
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Parents of children with retinoblastoma, the most common primary ocular malignant tumour in childhood, bear a heavy caregiving burden and are very susceptible to fatigue. However, little is known about their current status of fatigue and factors influencing fatigue; therefore,this study, based on the theory of unpleasant symptoms, and included 317 parents of children with retinoblastoma in China, whose general demographic data were collected, and on whom the fatigue severity scale (FSS), the generalized anxiety disorder (GAD-7) and 2-item patient health questionnaire (PHQ-2) were administered, from 9 March to 1 June 2020. The parents' FSS score and fatigue incidence were 4.

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Drug-related problems (DRPs) are critical medical issues during transition from hospital to home with high prevalence. The application of a variety of interventional strategies as part of the transitional care has been studied for preventing DRPs. However, it remains challenging for minimizing DRPs in patients, especially in older adults and those with high risk of medication discrepancies after hospital discharge.

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Purpose: To systematically review the available evidence regarding the prevalence and outcomes of cognitive frailty-a clinical syndrome characterized by the combination of physical frailty and cognitive impairment, without dementia-in community-dwelling older adults.

Method: The following databases were searched: PubMed, Web of Science, Embase, EBSCO, Cochrane Central Register of Controlled Trials, ProQuest, CNKI, Wanfang, VIP, and CBMdisc (inception to October 2, 2023).

Results: Twenty-four studies were included ( = 62,169) reporting a median prevalence of cognitive frailty among community-dwelling older adults of 12.

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Background: Omicron variants are currently the predominant circulating lineage worldwide and most cases are mild or asymptomatic. The Omicron variant is characterized by high transmissibility and immune evasion. Early identification of Omicron cases in clinical settings is crucial for controlling its spread.

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Background & Aims: Previous studies have shown that plant-rich dietary patterns, such as the Mediterranean diet, are associated with longer telomeres. However, no association has been found between vegetarian diet and telomere length. We hypothesized that the quality of plant-based diets plays an important role in telomere length.

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Purpose: The study aims to investigate the relationship among social support, health behavior self-efficacy, anxiety, and the physical activity (PA) levels of lung cancer survivors, and to analyze whether health behavior self-efficacy and anxiety mediate the relationship between social support and PA levels.

Methods: In a cross-sectional study of 1128 lung cancer survivors from 16 Chinese hospitals, we collected demographic data and administered the Social Support Rating Scale (SSRS), Self-Rated Abilities for Health Practices Scale (SRAHP), Anxiety Scale (AS), and International Physical Activity Questionnaire (IPAQ). SPSS 25.

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  • Traditional Chinese medicine suggests that herbs like Huangqi and Danggui can enhance Qi, boosting immunity to help fight tumors.
  • The study used various methods to test the effectiveness of these herbs in cancer treatment, finding that their combination is more potent than either one alone.
  • Key findings suggest that specific compounds in the combination target PIK3R1, enhancing immune response and showing significant anti-tumor effects, especially against breast cancer.
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Freezing is a popular method of food preservation with multiple advantages. However, it may change the internal composition and quality of food. This study aimed to investigate the effect of modified starch on the storage stability of frozen raw noodles (FRNs) under refrigerated storage conditions.

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Mycotoxins are toxic metabolites produced by fungal species, commonly exist in animal feeds, and pose a serious risk to human as well as animal health. But limited studies have focused on combined effects of no-observed adverse effect levels. In vivo study, 6 weeks old twenty-four mice were individually exposed to Deoxynivalenol (DON) at 0.

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Background/aim: Cancer-induced bone pain (CIBP) is one of the most common symptoms of bone metastasis of tumor cells. The hypothalamus may play a pivotal role in the regulation of CIBP. However, little is known about the exact mechanisms.

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