Publications by authors named "LiJuan Fan"

Esophageal leiomyoma is the most common benign intramural tumor of the esophagus. Despite being the most common benign tumor in its category, esophageal leiomyomas constitute only 1.2% of all esophageal tumors.

View Article and Find Full Text PDF

Background: Exercise therapy could improve physical and psychological health in patients with chronic kidney disease (CKD). This study aimed to investigate knowledge, attitudes and practices (KAP) towards exercise therapy among patients with CKD stage 5 on regular hemodialysis.

Methods: The cross-sectional study was conducted between August 1st and 30th, 2023; KAP and demographic characteristics of CKD-5 patients were assessed with self-distributed questionnaire and analyzed using logistic regression and structural equation modeling (SEM).

View Article and Find Full Text PDF

Cell-free DNA (cfDNA) has attracted increasing attention as a promising biomarker in liquid biopsy due to its crucial role in disease diagnosis. However, previous cfDNA detection methods are commonly based on the development of target-specific primers and integrated signal amplification strategies, which may induce false-positive results. This paper presents a sensitive yet accurate method for cfDNA detection that combines phosphorothioated-terminal hairpin creation with a self-priming extension process.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effectiveness of auricular acupressure (AA) as a treatment for insomnia caused by long-term use of the sedative estazolam.
  • It will involve 108 participants randomly assigned to AA, a sham treatment, or a traditional dosage reduction group, with a 4-week treatment and 1-month follow-up.
  • The outcomes will measure estazolam use, levels of certain brain chemicals, and participants' sleep quality, contributing to evidence on whether AA can help with drug-dependent insomnia.
View Article and Find Full Text PDF
Article Synopsis
  • - The study explores how gut microbiota affects polyamine metabolism, revealing that germ-free mice have higher polyamine levels in their colon compared to those with gut bacteria.
  • - It highlights that small RNA molecules from the gut can lower polyamine levels by inhibiting enzymes involved in their metabolism, which impacts recovery from conditions like colitis.
  • - Furthermore, a decrease in these small RNAs in colorectal cancer patients correlates with increased polyamine levels, suggesting that gut bacteria's role in regulating polyamine metabolism might be a target for treating related diseases.
View Article and Find Full Text PDF

Objective: To investigate the incremental value of pericoronary fat attenuation index (FAI) in routine coronary artery computed tomography angiography (CCTA) to identify culprit lesions in acute coronary syndrome (ACS).

Methods: We reviewed the CCTA data from 80 ACS patients and 40 individuals with stable coronary atherosclerosis. ACS patient plaques were categorized into culprit and nonculprit groups.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the effect of adding 4 mg estradiol valerate to progesterone for luteal support in IVF cycles where patients had low estrogen levels after hormone trigger.
  • Conducted at a reproductive center with 241 participants, the trial showed no significant difference in ongoing pregnancy rates between the estradiol group and the control group.
  • However, the estradiol group had no biochemical miscarriages and a higher clinical pregnancy rate in blastocyst transfers, suggesting potential benefits in these specific cases.
View Article and Find Full Text PDF

Introduction: In the realm of natural frozen-thawed embryo transfer (FET) cycles, the application of luteal phase support (LPS) is a prevalent practice, primarily due to its beneficial impact on reproductive outcomes. Among the various LPS medications, human chorionic gonadotropin (hCG) is one that exerts its function on both the corpus luteum and the endometrium.

Objective: To evaluate the effect of hCG administration as LPS on reproductive outcomes in natural FET cycles.

View Article and Find Full Text PDF

Background: To investigate the causal relationship between human papillomavirus (HPV) and lung cancer, we conducted a study using the two-sample Mendelian randomization (TSMR).

Method: Data from genome-wide association studies (GWAS) were analyzed with HPV E7 Type 16 and HPV E7 Type 18 as exposure factors. The outcome variables included lung cancer, small cell lung cancer, adenocarcinoma and squamous cell lung cancer.

View Article and Find Full Text PDF

Purpose: To investigate the primary causes and clinical characteristics of cystic encephalomalacia (CE) in children.

Methods: The clinical data of 50 children who were admitted to our hospital due to CE between January 2008 and December 2020 were retrospectively reviewed. Their primary causes, clinical manifestations and cranial magnetic resonance imaging features were analyzed.

View Article and Find Full Text PDF

Fisch. is an excellent ornamental plant in cold regions due to its unique ornamental ability and strong cold resistance. However, the flowering period of the population is only about 20 days, greatly limiting its potential uses in landscaping and the cutting flower industry.

View Article and Find Full Text PDF

Introduction: Mindfulness, self-efficacy, and self-regulation play vital roles in shaping the psychological well-being of English as a Foreign Language (EFL) learners. This study investigates the interconnections among these constructs and their implications for the psychological well-being of 527 Chinese EFL learners.

Methods: A cross-sectional study was conducted among Chinese EFL learners enrolled in a university in China.

View Article and Find Full Text PDF

Background: In this study, we aim to investigate the relationship between the attenuation of peri-coronary adipose tissue (PCAT) in patients with suspected coronary artery disease (CAD) and the assessment of coronary vascular functions using coronary flow reserve (CFR).

Methods: We included 364 patients who underwent N-NH positron emission tomography/computed tomography and coronary computed tomography angiography (CCTA). We determined the relationship between fat attenuation index (FAI), PCAT volume, and other qualitative CT-derived anatomic parameters with CFR.

View Article and Find Full Text PDF

One set of chronic gastrointestinal disorders called inflammatory bowel disease (IBD) is defined by persistent, non-specific inflammation. Abdominal pain, hematochezia, diarrhea, and other symptoms are among its clinical signs. Currently, managing and treating IBD remains a significant challenge.

View Article and Find Full Text PDF

Introduction: Cryptorchidism is a common genital disorder. Approximately 20% of azoospermic or infertile men reported having histories of cryptorchidism. Bilateral cryptorchidism may have been more condemned than unilateral cryptorchidism.

View Article and Find Full Text PDF
Article Synopsis
  • Melatonin plays key roles in regulating circadian rhythms, inflammation, and gut health, but its interaction with gut microbiota is not fully understood.
  • In studies with mice, it was found that those treated with antibiotics or raised in germ-free conditions had lower melatonin levels in their blood and higher levels in their colon.
  • The research identified that gut microbes influence melatonin production via specific signaling pathways, suggesting potential new treatment approaches for conditions linked to melatonin.
View Article and Find Full Text PDF

Serine metabolism is involved in the fate decisions of immune cells; however, whether and how de novo serine synthesis shapes innate immune cell function remain unknown. Here, we first demonstrated that inflammatory macrophages have high expression of phosphoglycerate dehydrogenase (PHGDH, the rate-limiting enzyme of de novo serine synthesis) via nuclear factor κB signaling. Notably, the pharmacological inhibition or genetic modulation of PHGDH limits macrophage interleukin (IL)-1β production through NAD accumulation and subsequent NAD-dependent SIRT1 and SIRT3 expression and activity.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the consistency between delayed enhancement cardiac magnetic resonance imaging (DE-CMR) and F-FDG PET imaging in assessing myocardial viability before coronary artery bypass grafting (CABG).
  • Data from 100 patients was analyzed both before and after CABG using DE-CMR, PET imaging, and echocardiography, with follow-up conducted 6-12 months post-surgery.
  • Results showed a high consistency (90.1%) between DE-CMR and PET imaging in measuring myocardial viability, with significant correlations found between delayed enhancement and improvements in heart function after surgery, highlighting the importance of identifying hibernating myocardium for predicting recovery.
View Article and Find Full Text PDF

Background: In the discourse on the heterogeneity of gender and environmental concern, gender equality awareness can further illuminate the complexity of gender and environmental concern across different cultural backgrounds.

Objective: Differing from prior research, our study focuses on exploring the relationship between different genders, gender equality awareness, and environmental concern, as well as investigating whether gender equality awareness has distinct effects on environmental concern among different genders.

Methods: Utilizing data from the 2021 China General Social Survey (CGSS), we conducted a theoretical investigation into gender differences in environmental concern.

View Article and Find Full Text PDF

Objective: To compare the hypertensive disorders of pregnancy (HDP) risk between vaginal and intramuscular (IM) progesterone in programmed frozen-thawed embryo transfer (FET) cycles.

Methods: This was a retrospective cohort study at a tertiary hospital, and only women who achieved ongoing pregnancy after programmed FET between January 2018 and June 2022 were included. Women with chronic hypertension before pregnancy or with history of gestational hypertension or pre-eclampsia in previous pregnancies were excluded.

View Article and Find Full Text PDF

The plant disease Colletotrichum coccodes, which lowers potato yields, poses a severe danger to the booming potato industry. Isolated plant endophytic bacteria from highland pasture can produce a variety of metabolites that lessen the risk that the pathogen C. coccodes poses to plant growth and development.

View Article and Find Full Text PDF

Preparing new fluorescent materials for individualized and customized anti-counterfeiting applications to meet needs from the rapid development of e-commerce is of great significance. This paper reports the preparation of dynamic color-changing fluorescent polymer nanoparticles (PNPs) by constructing a fluorescence resonance energy transfer (FRET) pair between aggregation-induced emission (AIE) structures and photochromic structures. At first, methyl methacrylate (MMA) was used as the main monomer and tetraphenylethylene (TPE, a typical AIE structure) modified methacrylate (TPE-MA) and photochromic spiropyran (SP) modified methacrylate (SP-MA) as minor monomers were copolymerized to obtain the ternary copolymer PMMA-TPE-SP.

View Article and Find Full Text PDF