Publications by authors named "LiHui Yang"

Background: This study explores the influence of family function on depression in older adults with chronic comorbidities and the mediating roles of cognitive fusion and coping styles.

Methods: The Family Adaptation Partnership Growth Affection and Resolve Index, Patient Health Questionnaire-9, Cognitive Fusion Questionnaire-Fusion, and Trait Coping Style Questionnaire were used to survey 448 community-dwelling older adults with chronic comorbidities. A mediation test was conducted using the Process 4.

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Background: Stress is significantly associated with depressed mood in nurses. However, it remains unclear whether the mechanisms by which two types of stress-childhood adversity and perceived stress-affect depression are identical. This study aims to investigate the relationship between stress (including childhood adversity and perceived stress) and depression, as well as the mediating role of coping profiles.

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In this study, hydrodynamic cavitation technology was utilized to prepare conjugates of soy protein isolate (SPI) with polyphenols, including resveratrol (RA) and polydatin (PD) from the stilbene category, as well as arctiin (AC) and magnolol (MN) from the lignan category. To investigate the effects of hydrodynamic cavitation treatment on the interactions between SPI and these polyphenols, the polyphenol binding capacity with SPI was measured and the changes in the exposed sulfhydryl and free amino contents were analyzed. Various methods, including ultraviolet-visible spectroscopy, fluorescence spectroscopy, Fourier transform infrared spectroscopy, and circular dichroism spectroscopy, were also used to characterize the structural properties of the SPI-polyphenol conjugates.

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Study Design: A retrospective case-control study.

Objective: To compare the clinical efficacy of endoscopic (Endo) and open posterior lumbar interbody fusion (PLIF) in treating lumbar spondylolisthesis.

Background: Endo-PLIF has emerged as a new technique for treating lumbar spondylolisthesis.

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Article Synopsis
  • The study explored the effectiveness of an improved digital ELISA technique for detecting plasma biomarkers related to Alzheimer's disease (AD) in patients across varying cognitive stages.
  • The results indicated that plasma levels of phosphorylated tau (p-tau181) and amyloid-beta (Aβ42 and Aβ40) were significantly different among normal cognition, mild cognitive impairment, and AD groups, showcasing p-tau181's strong predictive value for AD.
  • Overall, the findings suggest that plasma p-tau181 and the Aβ42/Aβ40 ratio could serve as valuable diagnostic tools for early detection of AD and mild cognitive impairment.
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Background: Diabetic retinopathy (DR) is one of the most common complications of diabetes worldwide. The aim of this study was to assess the prevalence of DR in hospitalized patients with type 2 diabetes (T2DM) in Tibet and to identify risk factors that may influence the occurrence of DR.

Methods: This was a cross-sectional study conducted in a third-class hospital in the Tibet Autonomous Region.

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Nonalcoholic fatty liver disease (NAFLD), a metabolic disease associated with obesity and type 2 diabetes. Due to its complex pathogenesis, there are still limitations in the knowledge of the disease. To date, no drug has been approved to treat NAFLD.

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Liver cancer is a heterogeneous disease characterized by poor responses to standard therapies and therefore unfavourable clinical outcomes. Understanding the characteristics of liver cancer and developing novel therapeutic strategies are imperative. Ferroptosis, a type of programmed cell death induced by lipid peroxidation, has emerged as a potential target for treatment.

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Objective: To investigate the cognitive function and nutritional status of elderly patients with gastric cancer during perioperative period, and to analyze their correlation.

Methods: Aged patients undergoing gastric cancer surgery in The Affiliated Cancer Hospital of Shandong First Medical University from March to October 2021 were selected as the subjects of this study. The monitoring data of cognitive function and nutritional status were retrospectively analyzed from 1 to 3 days before surgery, 1 and 3 days after surgery, 7 days after surgery (before discharge) and 30 days after surgery to analyze the correlation between cognitive function and nutritional status in elderly patients with gastric cancer.

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In this work, the dynamic marine atmospheric corrosion behavior of AZ91 Mg alloy sailing from Yellow Sea to Western Pacific Ocean was studied. The corrosion rates were measured using the weight loss method. The microstructure, phase, and chemical composition of corroded samples were investigated by SEM, EDS, XRD, and XPS.

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Introduction: Symptomatic intracranial hemorrhage (sICH) is a serious complication of acute ischemic stroke (AIS) after endovascular treatment (EVT). Limited data exist regarding predictors and clinical implications of sICH after EVT, underscoring the significance of identifying risk factors to enhance prevention strategies. Therefore, the main objective of this study was to evaluate the incidence of sICH and identify its predictors after EVT in patients with large infarct core-AIS in the pre-circulation stage.

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The appearance of triboelectric nanogenerators (TENG) provides a promising energy technology for harvesting abundant water wave energy. Here, the design and fabrication of a swinging origami-structured TENG (SO-TENG) tailored specifically for water wave energy harvesting are presented. The design incorporates an oscillating structure weighted at the bottom, inducing reciprocating motion propelled by the inertia of passing water waves.

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Article Synopsis
  • Spondylocostal dysostosis (SCDO) is a group of bone problems that affect the spine and ribs, often due to genetic issues.
  • Scientists studied a Chinese fetus with SCDO to find out what caused the condition by looking at its DNA and conducting special tests.
  • They discovered a new genetic change in a specific gene called LFNG that seems to affect its function, and this case helps to understand more about SCDO and similar cases.
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Background And Purpose: Perforator artery disease (PAD) is an important subtype of ischemic stroke. The risk factors affecting the prognosis of patients with PAD are unclear. This study aimed to investigate the risk factors affecting the unfavorable prognosis of PAD.

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Hemorrhagic transformation can complicate ischemic strokes after recanalization treatment within a time window that requires early intervention. To determine potential therapeutic effects of matrilin-3, rat cerebral ischemia-reperfusion was produced using transient middle cerebral artery occlusion (tMCAO); intracranial hemorrhage and infarct volumes were assayed through hemoglobin determination and 2,3,5-triphenyltetrazoliumchloride (TTC) staining, respectively. Oxygen-glucose deprivation (OGD) modeling of ischemia was performed on C8-D1A cells.

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Immunotherapy has become an effective method for the treatment of a variety of malignant tumors. However, with the development of immunotherapy, the phenomenon of hyperprogression in patients with cancer has gradually attracted attention. Hyperprogression refers to a condition in which the progression of a disease during treatment of a patient with cancer is suddenly accelerated.

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Article Synopsis
  • The study focuses on improving triboelectric nanogenerators (TENG) for cleaner energy in electrochemical processes, as their limited output has been a significant barrier.
  • Researchers developed a porous and high-roughness PDMS material by mixing it with chitosan, resulting in a TENG that significantly outperformed traditional designs.
  • The new TENG, tested under mechanical force, achieved notable voltage (77.1 V) and current density (33.9 mA/m), and was further used in an electrochemical protection system, highlighting its potential as a clean energy source.
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The objective of this study was to explore the clinical characteristics and prognosis of diabetic foot in hospitalized patients with diabetes in Tibet. To achieve that, patients hospitalized in People's Hospital of Tibet Autonomous Region and diagnosed with diabetic foot ulcer (DFU) from January 1, 2016 to December 31, 2020 were enrolled in the study, and DFU cases of Peking University First Hospital were collected as control group. Analysis and comparison of clinical characteristics of DFU in plateau and plain areas were conducted.

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Electrochemical oxygen reduction reaction (ORR) is an attractive and alternative route for the on-site production of hydrogen peroxide (H O ). The electrochemical synthesis of H O in neutral electrolyte is in early studying stage and promising in ocean-energy application. Herein, N-doped carbon materials (N-C ) with different N types are prepared through the pyrolysis of zeolitic imidazolate frameworks.

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Hepatocellular carcinoma (HCC) is a deadly malignancy with high genetic heterogeneity. TP53 mutation and c-MET activation are frequent events in human HCCs. Here, we discovered that the simultaneous mutations in TP53 and activation of c-MET occur in ~20% of human HCCs, and these patients show a poor prognosis.

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Background: To investigate the clinical characteristics of Addison's disease caused by adrenal tuberculosis in Tibet. After the anti-tuberculosis treatment, the clinical features between continuous glucocorticoid therapy and glucocorticoid withdrawal were analyzed.

Methods: Clinical data of patients with Addison's disease caused by adrenal tuberculosis diagnosed in The People's Hospital of Tibet Autonomous Region from January 2015 to October 2021 were collected and analyzed.

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Background: Lower diabetes prevalence and cardiovascular mortality have been observed in residents at a higher altitude. Leptin is associated with incident diabetes and adverse cardiovascular outcomes, and our aim was to investigate the association of living altitude with serum leptin concentrations.

Methods: Two cross-sectional surveys were used in this study, including native populations living at Tibet (high altitude) and Beijing (low altitude).

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