Noninvasive scoring system for significant inflammation related to chronic hepatitis B.

Although a liver stiffness measurement-based model can precisely predict significant intrahepatic inflammation, transient elastography is not commonly available in a primary care center. Additionally, high body mass index and bilirubinemia have notable effects on the accuracy of transient elastography. The present study aimed to create a noninvasive scoring system for the prediction of intrahepatic inflammatory activity related to chronic hepatitis B, without the aid of transient elastography.

Changes in DTI parameters in the optic tracts of macaque monkeys with monocular blindness.

For humans and non-human primates, the alteration of the visual pathway's white matter fibers after visual deprivation has been partially explored. However, the changes in the optic tracts after the transection of the optic nerve have not been well characterized. In the current study, we attempted to investigate the differences in optic tracts between normal and unilateral optic nerve transected macaque monkeys using diffusion tensor imaging (DTI).

In vivo USPIO-enhanced MR signal characteristics of secondary degeneration in the ipsilateral substantia nigra after middle cerebral artery occlusion at 3T.

Background And Purpose: Ultrasmall superparamagnetic iron oxide (USPIO) particles to enhance MRI have been used to study neuroinflammation in vivo. Our purpose was to observe the USPIO-enhanced MR signal alterations in the primary ischemic lesion and ipsilateral substantia nigra after middle cerebral artery occlusion (MCAO) to verify the subsequent sequelae of neuroinflammation seen in the primary ischemic focus and secondary degeneration region.

Materials And Methods: Sprague-Dawley rats were subjected to transient MCAO.

Detection of brain lesions at the skull base using diffusion-weighted imaging with readout-segmented echo-planar imaging and generalized autocalibrating partially parallel acquisitions.

Objective: To analyze the value of readout-segmented echo-planar imaging (rs-EPI) with parallel imaging and a two-dimensional (2D) navigator-based reacquisition technique in the detection of brain lesions at the skull base.

Materials And Methods: A total of 54 patients (male 37, female 17) with suspected skull-base intracranial lesions underwent magnetic resonance imaging (MRI), including pre-T1 weighted imaging, T2-weighted imaging, Fluid Attenuated Inversion Recovery (FLAIR), standard single shot echo-planar imaging diffusion weighted imaging (ss-EPI DWI) and rs-EPI DWI, post-contrast T1-weighted. The total number of lesions and the number of lesions at different sites on all MRI sequences were used as reference measures.

[The expression and significance of Notch1 in the human kidney tubular cell transdifferentiation induced by TGF-β(1);].

Aim: To explore the dynamic expression and significance of Notch1 in the human kidney tubular epithelial cell transdifferentiation (KTECT)induced by TGF-β(1);.

Methods: Normal human kidney epithelial cell line (HK-2) was cultured and then divided into blank group, and TGF-β(1);(10 ng/mL) induced group. At the 12 h, 24 h, 48 h and 72 h, the morphologic changes of HK-2 cells were observed under an inverted phase contrast microscope.

[Effect of organs biomass by drought stress on the leaf growing stage of Angelica dahurica var. formosana].

Objective: To study the effect of natural drought stress conditions on Angelica dahurica var. formnosana vegetative organs biomass accumulation and allocation in leaf growing season. To discuss the changing law of Angelica dahurica var.

Detection of pulmonary embolism comparison between dual energy CT and MR angiography in a rabbit model.

Rationale And Objectives: The purpose of this study was to compare the efficacy of dual-energy computed tomography (DECT), time-resolved magnetic resonance (MR) imaging (MRI) perfusion measurements, and high-resolution MR angiography (MRA) for the detection of pulmonary embolism (PE) in a rabbit model.

Materials And Methods: Two hours after Gelfoam (n = 16) or saline (n = 2) injection into the femoral vein, 18 rabbits were first imaged using dual-energy computed tomographic pulmonary angiography (CTPA), from which blood flow imaging (BFI) were produced. Next, the rabbits underwent time-resolved MR perfusion measurements and MRA using a 3.