Publications by authors named "Li-xin Huang"

Peripheral nerve injury (PNI) can result in severe disabilities, profoundly impacting patients' quality of life and potentially endangering their lives. Therefore, understanding the potential molecular mechanisms that facilitate the regeneration of damaged nerves is crucial. Evidence indicates that Schwann cells (SCs) play a pivotal role in repairing peripheral nerve injuries.

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Ischemic stroke is a significant burden on human health worldwide. Carotid Atherosclerosis stenosis plays an important role in the comprehensive assessment and prevention of ischemic stroke patients. High-resolution vessel wall magnetic resonance imaging has emerged as a successful technique for assessing carotid atherosclerosis stenosis.

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Article Synopsis
  • Intracranial atherosclerotic stenosis (ICAS) is a key factor in ischemic strokes, and this study examines how high-resolution vessel wall imaging (HR-VWI), hemodynamics, and blood inflammation relate to symptomatic ICAS (sICAS).
  • Researchers analyzed data from 32 patients with middle cerebral artery stenosis by examining plaque characteristics, blood flow dynamics, and inflammatory markers to uncover correlations and predictors of sICAS.
  • Findings showed that plaque enhancement and a measure called wall shear stress ratio (WSSR) are closely linked to sICAS, with WSSR identified as a significant independent risk factor.
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Article Synopsis
  • Intracranial atherosclerotic stenosis (ICAS) significantly contributes to ischemic strokes, and this study explores how high-resolution vessel wall imaging (HR-VWI) can evaluate the characteristics of ICAS plaques.
  • The research involved analyzing data from 91 adult patients with ICAS to measure plaque enhancement and its relationship to factors like plaque burden and symptomatic status.
  • Results indicated that greater plaque burden correlated with increased enhancement of plaques, and both plaque characteristics were linked to symptomatic ICAS, with plaque enhancement identified as a key independent risk factor.
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Background And Objective: The application of wedge-shaped bone grafts can increase the biomechanical stability of knee during the medial open-wedge high tibial osteotomy (MOWHTO) by reducing the von Mises stress of the medial plate and lateral cortical hinge area. However, the optimal position of bone grafts it remains unclear, so we aimed to determine search for the optimal position of the bone grafts in MOWHTO by using finite element analysis.

Methods: In the finite element analysis, MOWHTO models were established with three different osteotomy distraction heights and assembled into four groups according to different conditions, including the no bone grafts (NBG) group, the anterior bone grafts (ABG) group, the middle bone grafts (MBG) group, and the posterior bone grafts (PBG) group.

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Background And Purpose: Gadolinium enhancement on high-resolution vessel wall imaging (HR-VWI) is an imaging marker of intracranial atherosclerotic stenosis (ICAS) plaque instability. This study aimed to evaluate the relationships between hematological inflammatory indicators and the enhancement of ICAS plaques and to search for hematological indicators that can predict ICAS plaque instability.

Methods: Consecutive adult patients diagnosed with ICAS from April 2018 to December 2021 were recruited retrospectively, and every patient underwent HR-VWI.

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The resistance to dieldrin gene (RDL) encodes the primary subunit of the insect ionotropic γ-aminobutyric acid (GABA) receptor (GABAR), which is the target of phenylpyrazole and isoxazoline insecticides. The splice variants in exons 3 and 6 of RDL, which have been widely explored in many insects, modulate the agonist potency of the homomeric RDL GABAR and potentially play an important role in the development of insects. In the present study, four splice variants of exon 9 were identified in RDL of the small brown planthopper, Laodelphax striatellus (LsRDL), resulting in LsRDL-9a, LsRDL-9a', LsRDL-9b, and LsRDL-9c.

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We performed this meta-analysis to examine the diagnostic accuracy of MRI for the diagnosis of anterior cruciate ligament (ACL) injury in comparison to arthroscopy. We also compared the diagnostic accuracy of MRI with magnetic field intensities (MFI) greater than or equal to 1.5T with those below 1.

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In order to investigate the dynamics of nitrogen and sulfur wet deposition in subtropical forest ecosystem, one typical forest stand, evergreen broad-leaved forest, at Simian Mountain located in Chongqing was selected in this research. Based on field monitoring, effects of precipitation, throughfall, litterfall, and groundwater runoff of the typical forest stand on the quality of water of Simian Mountain were investigated from September 2012 to August 2013. Results showed that the rainfall of Simian Mountain was apparently acidic, with average pH of 4.

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Posterior dislocation of the shoulder (PSD) is a rare injury; the diagnosis is often missed on initial examination. We present a systematic review of the current literature and discuss the key of the diagnosis of PSD. We searched the MEDLINE, PubMed, EMBASE, MD Consult, and the Cochrane Controlled Trial Register databases for the articles according to our eligibility criteria.

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Total gaseous mercury fluxes of forested field soils in the subtropical forest zones, Chongqing, Southwestern China were continually monitored from April 2011 to March 2012 to provide insights into the characteristics of gaseous mercury flux with conifer-broadleaf forest covers. Samples were collected from surfaces of forest fields as the most representative terrestrial surfaces in Jinyun Mountain. Simultaneously, meteorological parameters at the soil level relating to GEM fluxes, such as soil temperature, air humidity, and solar radiation were analyzed, and variations of atmospheric GEM concentration were examined.

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Background: Several methods have been reported for the conjugation of proteins with polysaccharides. Protein-polysaccharide conjugates can be formed by traditional dry heating, but this process is not attractive from an industrial viewpoint, and no commercial conjugates have been manufactured in this way. In the present study, in order to develop a more practical reaction method, macromolecular crowding was used to attach polysaccharides to proteins.

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The distribution of microbial communities in the Menggulin (MGL) and Ba19 blocks in the Huabei Oilfield, China, were studied based on 16S rRNA gene analysis. The dominant microbes showed obvious block-specific characteristics, and the two blocks had substantially different bacterial and archaeal communities. In the moderate-temperature MGL block, the bacteria were mainly Epsilonproteobacteria and Alphaproteobacteria, and the archaea were methanogens belonging to Methanolinea, Methanothermobacter, Methanosaeta, and Methanocella.

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A prospective randomized study was performed to compare the clinical and radiological results of primary total knee arthroplasties (TKAs) using a mini-midvastus approach or a mini-medial parapatellar approach in 134 patients. The mini-midvastus approach was used on 68 patients (group A) and the mini-medial parapatellar approach on 66 patients (group B). All knees were implanted with the same posterior-stabilized prosthesis by the same surgeon (T.

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Objective: To describe the authors' surgical technique and to evaluate the final functional outcome of surgical treatment of the "terrible triad of the elbow".

Methods: Eight patients identified with "terrible triad" injury patterns, including posterior elbow dislocation, radial head fracture and coronoid fracture, were available for a minimum of 11 months follow-up. Evaluation of functional outcome was based on Mayo elbow performance, Broberg-Morrey scores, and the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire.

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Objective: Xinmailong, a compound extracted from Periplaneta americana, is used for the treatment of cardiovascular diseases. This study investigated the effects of Xinmailong on myocardial hypoxia-inducible factor-1alpha (HIF-1alpha) and plasma endothelin-1(ET-1) levels in neonatal rats with asphyxia and explored the protection mechanism of Xinmailong in hypoxia-ischemic myocardial injury.

Methods: Seven-day-old Sprague-Dawley rats were randomly divided into three groups (n=30 each): sham-operated, asphyxia, Xinmailong-treated asphyxia.

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Objective: To evaluate the long-term clinical results and the factors that influences the outcomes of the revision open lumbar discectomy by fenestration.

Methods: Fifty-one patients, who underwent the second open discectomy by fenestration from January 1 1988 to December 31 1994, were followed for an average of 146.8 months (range, 120 to 203 months).

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Aim: To determine the secondary structure of insulin encapsulated within liposomes.

Methods: The secondary structure of insulin, mixture of insulin with liposomes (I) and insulin liposomes (II) were determined by Fourier transform infrared (FTIR) spectroscopy.

Results: The figures of secondary structure of insulin, sample I and II were similar.

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