Publications by authors named "Li-wei Wei"

NiFe layered double hydroxide (LDH) currently are the most efficient catalysts for the oxygen evolution reaction (OER) in alkaline environments. However, the development of high-performance low cost OER electrocatalysts using straightforward strategies remains a significant challenge. In this study, we describe an innovative microbial mineralization-based method for in situ-induced preparation of NiFe LDH nanosheets loaded on nickel foam and demonstrate that this material serves as an efficient oxygen evolution electrocatalyst.

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  • Pseudomyxoma peritonei (PMP) is a rare tumor that mimics malignant behavior, traditionally treated with surgical resection and chemotherapy, though results are often poor.
  • Newer treatments combining cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are being studied for their safety and effectiveness in treating PMP.
  • An observational study of 186 PMP patients treated with CRS + HIPEC revealed a median age of 56, a 30-day postoperative fatality rate of 2.7%, and a significant incidence of complications, particularly anemia, although most patients did not achieve satisfactory CRS outcomes.
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Context: In order to obtain environmentally friendly emulsion explosives formulations with higher power, based on zero oxygen balance, formulations of titanium hydride (TiH)-high-power emulsion explosives were optimally designed. The results show that the zero oxygen balance formulation produces almost no toxic and harmful gases. The detonation temperature and detonation heat are increased.

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  • The study investigates gene expression and miRNA regulation in silkworms (Bombyx mori) during and after death to understand biological processes that continue post-mortem.
  • Researchers found 171 genes that showed sustained changes in expression after death, mainly linked to nerve signaling, immunity, and transport functions.
  • They identified specific mRNA-miRNA interactions that play roles in stress hormone regulation and transcription activity, validated through experiments, offering insights into biological mechanisms active even after death.
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The excessive length of the superior cornu of the thyroid cartilage is extremely rare, and the etiology is unknown. Few reports of this condition exist in the literature. The objective of the present study was to present a rare case of unilateral excessive length of the superior cornu of the thyroid cartilage.

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Background: Foreign body-induced cancer is a traditional way of understanding cancer development. The induction of cancers by exogenous foreign bodies has been identified in many organs. However, small bowel adenocarcinoma induced by foreign bodies has not been reported in the literature, although the incidence of small bowel adenocarcinoma is increasing globally.

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This study aims to investigate the role and mechanism of Gusong Qianggu Decoction(GSQG) in attenuating bone loss in ovariectomized mice by targeting the endoplasmic reticulum stress(ERS)-induced apoptosis of osteocytes. After the modeling of osteoporosis in mice with bilateral ovary removal(OVX), 60 mice were randomized by the random number method into six groups: sham,model, low-, medium-, and high-dose GSQG(GSQG-L, GSQG-M, and GSQG-H, respectively), and estradiol(E_2), with 10 mice in each group. The mice in each group were administrated with corresponding drugs by gavage one month after surgery and the administration lasted for 3 months.

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Fabry-Perot cavities are widely used in precision interferometric applications. Various techniques have been developed to achieve the resonance condition via the direct interrogation of the cavity with the main laser field of interest. Some use cases, however, require a surrogate field for cavity control.

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High-finesse optical cavities have a wide range of applications, some of which are bichromatic. The successful operation of high-finesse bichromatic cavities can demand careful control on the temperature dependence of the wavelength-dependent reflection phase from the dielectric mirror coatings that constitute the optical cavity. We present dielectric coating designs that are optimized for minimal differential change in the reflection phase between a quasi-second-harmonic field and its fundamental field under temperature changes.

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Background: Neuroendocrine carcinoma (NEC) of the extrahepatic bile duct is very rare, and the treatment and prognosis are unclear. Herein, we report the case of a middle-aged female with primary large cell NEC (LCNEC) of the common hepatic duct combined with distal cholangiocarcinoma (dCCA). Additionally, after a review of the relevant literature, we summarize and compare mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) and pure NEC to provide a reference for selecting the appropriate treatment and predicting the prognosis of this rare disease.

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Objective: Atherosclerosis is a chronic inflammatory disease of the arteries, and its pathogenesis is related to endothelial dysfunction. It has been found that the protein convertase subtilin/kexin9 type (PCSK9) plays an important role in AS, but its specific mechanism is still unclear.

Methods: In this study, we first cultured human umbilical vein endothelial cells (HUVECs) with 50 or 100μg/ml oxidized low-density lipoprotein (ox-LDL) for 24 hours to establish a coronary atherosclerosis cell model.

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To explore the causes of red tides in Qinhuangdao coastal water, we conducted surveys on both water quality and red tides during April to September of 2022 and analyzed the relationships between main environmental factors and red tide organisms through the factor analysis and canonical correspondence analysis. The results showed that there were eight red tides along the coast of Qinhuangdao in 2022, with a cumulative blooming area of 716.1 km.

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Background: For resectable hepatocellular carcinoma (HCC), radical hepatectomy is commonly used as a curative treatment. However, postoperative recurrence significantly diminishes the overall survival (OS) of HCC patients, especially with microvascular invasion (MVI) as an independent high-risk factor for recurrence. While some studies suggest that postoperative adjuvant therapy may decrease the risk of recurrence following liver resection in HCC patients, the specific role of adjuvant therapies in those with MVI remains unclear.

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  • Baijiu is a popular Chinese alcoholic beverage, and its quality relies heavily on the fermentation process where yeast plays a crucial role in developing aroma and flavor.
  • Research identified eight dominant yeast species during baijiu fermentation, with one strain, Clavispora lusitaniae YX3205, showing the highest flavor substance content and significant ethanol tolerance.
  • The study suggests that using C. lusitaniae YX3205 can enhance baijiu's flavor, making it an important strain for improving the beverage's overall quality.
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Recently, catalytic valorization of biomass-derived furans has received growing interest. 5-Aminomethyl-2-furancarboxylic acid (AMFC), a furan amino acid, holds great promise in the aeras of polymer and pharmaceutical, but its synthesis remains limited. In this work, we report a chemobiocatalytic route toward AMFC by combining laccase-TEMPO system and recombinant Escherichia coli (named E.

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  • TLR/IL-1R signaling is essential for detecting harmful pathogens and triggering immune responses, with intracellular regulators playing a key role.
  • BLK is identified as a positive regulator of this signaling pathway, where its absence leads to reduced inflammatory cytokine production and increased resistance to IL-1β.
  • The study reveals that BLK interacts with IL1R1 and IL1RAcP, and upon stimulation, it activates itself and phosphorylates TOLLIP, promoting its dissociation from IRAK1 to enhance immune signaling.
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Extracellular vesicles (EVs) mediate inflammation, immune responses, gut barrier integrity, and intestinal homeostasis. Recently, the application of EVs in the treatment of inflammatory bowel disease (IBD) has been under intensive focus. Some studies have been conducted in animal models of colitis, while systematic reviews and meta-analyses are lacking.

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Objective: The purpose of this study was to investigate the utility of contrast-enhanced ultrasound (CEUS) in percutaneous renal space-occupying lesion puncture biopsy.

Methods: Ultrasound (US)-guided percutaneous needle biopsies were performed on 55 patients with renal space-occupying lesions, and the results were analyzed retrospectively. The US group included 36 patients receiving conventional US, and the contrast-enhanced ultrasound (CEUS) group included 22 patients, including 19 patients receiving CEUS directly and 3 patients receiving additional enhanced ultrasound due to the first conventional ultrasound puncture failure.

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Background: Ultrasound is a vital tool for the diagnosis and management of colorectal cancer (CRC). Contrast-enhanced ultrasound (CEUS) is a non-invasive, safe, and cost-effective method for evaluating tumour blood vessels, that play a crucial role in tumour growth and progression.

Aim: To explore CEUS's role in the quantitative evaluation of CRC blood vessels and their correlation with angiogenesis markers and prognosis.

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Antibiotics and pesticides are widespread in most rivers and lakes due to the overuse of antibiotics and pesticides, but there are few methods for simultaneous analysis of antibiotics and pesticides in aquatic environments. To address this knowledge gap, a concise and sensitive analytical method is proposed in which three classes of human and veterinary drugs (sulfonamides, macrolides, and hormones) and two classes of pesticides (organophosphorus and neonicotinoids) are simultaneously extracted and determined in surface water. The solid-phase extraction column with Cleanert PEP-2 was preconditioned sequentially with 6 mL of methanol, ultrapure water, and citric acid buffer (pH 3.

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  • Viral infections activate the transcription factor IRF3, critical for robust antiviral responses, but the precise mechanism for its full activation is not well understood.
  • Researchers identified the kinase BLK as a key player that enhances IRF3 activation and boosts antiviral immune responses, as BLK deficiency leads to reduced interferon production and higher susceptibility to viral infections.
  • Mechanistically, viral infection induces BLK autophosphorylation, enabling BLK to phosphorylate IRF3, which is essential for IRF3's further activation and effective antiviral responses.
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To conduct a study that examined the molecular epidemiology and pathogenesis of Senftenberg isolates associated with an outbreak of foodborne disease in Guizhou Province and to provide a reference basis for the traceability of foodborne salmonellosis outbreaks and clinical diagnosis and treatment in the province. Fourteen strains of suspected isolated from patient stool and food samples were used for pathogenic identification and serotyping by biochemical and mass spectrometry methods. Fourteen types of antibiotics were tested for drug sensitivity by the microbroth dilution method, and molecular typing was performed by pulsed-field gel electrophoresis (PFGE) and whole genome sequencing (WGS).

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  • In arthropods, the Down Syndrome Cell Adhesion Molecule (Dscam) gene can produce a vast number of splice variants, with significant variation noted in the Chinese mitten crab, where specific exons can create numerous alternatives.
  • Recent research using Illumina sequencing identified even more splice variants, potentially leading to over 50,000 unique Dscam protein variants in this species.
  • The study found that one of these proteins, EsDscam-Ig1-Ig7, can bind to certain bacteria and enhance immune responses, while lacking direct antibacterial properties, suggesting a crucial role in immunity through phagocytosis and bacterial clearance.
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Nitrogen (N) fertilizer acts as the main driving force for agricultural productivity improvement. However, overuse of N fertilizer has caused severe effects to environment and ecosystem. Thus, it is pivotal to improve nitrogen use efficiency (NUE) for future sustainable agriculture.

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