Publications by authors named "Li-tao Sun"

Article Synopsis
  • Ovarian cancer has the highest death rate among women's cancers and is primarily screened using ultrasound, but accurate assessment is difficult due to complex images and anatomy.
  • Researchers developed an AI system called the Ovarian Multi-Task Attention Network (OvaMTA) to automate the detection, segmentation, and classification of ovarian masses from ultrasound images.
  • The AI system was trained with thousands of images, validated with real-world tests, and compared against physician assessments to evaluate its effectiveness in aiding diagnoses of ovarian cancer.
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Objective: This study investigated the epidemic characteristics and spatio-temporal dynamics of hemorrhagic fever with renal syndrome (HFRS) in Qingdao City, China.

Methods: Information was collected on HFRS cases in Qingdao City from 2010 to 2022. Descriptive epidemiologic, seasonal decomposition, spatial autocorrelation, and spatio-temporal cluster analyses were performed.

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Purpose: To develop and validate a nomogram based on 3D-PDU parameters and clinical characteristics to predict LNM and LVSI in early-stage cervical cancer preoperatively.

Materials And Methods: A total of first diagnosis 138 patients with cervical cancer who had undergone 3D-PDU examination before radical hysterectomy plus lymph dissection between 2014 and 2019 were enrolled for this study. Multivariate logistic regression analyses were performed to analyze the 3D-PDU parameters and selected clinicopathologic features and develop a nomogram to predict the probability of LNM and LVSI in the early stage.

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Drug local delivery system that directly supply anti-cancer drugs to the tumor microenvironment (TME) results in excellent tumor control and minimizes side effects associated with the anti-cancer drugs. Immune checkpoint inhibitors (ICIs) have been the mainstay of cancer immunotherapy. However, the systemic administration of ICIs is accompanied by considerable immunotherapy-related toxicity.

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-GaO nanostructures are attractive wide-band-gap semiconductor materials as they exhibit promising photoelectric properties and potential applications. Despite the extensive efforts on -GaO nanowires, investigations into -GaO nanotubes are rare since the tubular structures are hard to synthesize. In this paper, we report a facile method for fabricating -GaO nanotubes using pre-synthesized GaSb nanowires as sacrificial templates.

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Hydrothermal synthesis is a highly efficient way to yield multiform Te nanosheets. However, the growth mechanisms and property discrepancies between different types of Te nanosheets are still unclear. In this paper, we perform an investigation on this issue by monitoring the hydrothermally synthesized Te nanosheets at different growth stages with transmission electron microscopy and electrical tests.

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Article Synopsis
  • The study evaluated a combination model using traditional statistics and deep learning to diagnose malignant breast nodules via Doppler ultrasound.
  • It established separate prediction models based on ultrasound features and clinical data, and then compared their diagnostic accuracy using a test group.
  • The results showed that the combined model significantly outperformed both the traditional statistical and deep learning models, indicating its strong diagnostic capabilities.
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Objective: The accurate preoperative differentiation of benign and malignant adnexal masses, especially those with complex ultrasound morphology, remains a great challenge for junior sonographers. The purpose of this study was to develop and validate a nomogram based on the Ovarian-Adnexal Reporting and Data System (O-RADS) for predicting the malignancy risk of adnexal masses with complex ultrasound morphology.

Methods: A total of 243 patients with data on adnexal masses with complex ultrasound morphology from January 2019 to December 2020 were selected to establish the training cohort, while 106 patients with data from January 2021 to December 2021 served as the validation cohort.

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Binary metallic nanocrystals are attractive as they offer an extra degree of freedom for structure and phase modulation to generate synergistic effects and extraordinary properties. However, whether the binary structures and phases at the nanoscale still follow the rules established on the bulk counterparts remains unclear. In this work, AuAg nanorods were used as a sample to probe into this issue.

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Background: The common area of breast cancer metastases are bone, lung and liver. Brachial plexus metastasis from breast cancer is extremely rare. We report a case of subclavian brachial plexus metastasis from breast cancer 6 years postoperative, which were detected by ultrasound, magnetic resonance imaging (MRI) and F-fluorodeoxyglucose positron emission tomography and computed tomography (FDG-PET/CT).

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Background: Primary hepatic angiosarcoma (PHA) is a rare malignant tumor of the vascular endothelium. Clinical manifestations and laboratory and imaging examinations often lack specificity for PHA. We report a case of PHA, and describe the ultrasound characteristics and characteristic changes in laboratory values associated with PHA.

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Modulation of gas-phase nanoparticles is unmethodical as there is a lack of information on the growth kinetics and its determinants. Here, we developed a novel evaporation-and-deposition (EAD) method inside a transmission electron microscope which enables direct visualization of the nucleation, growth, coalescence and shape/phase evolution of gas-phase fabricated nanoparticles. Using a BiPbSnIn alloy as a sample, the critical factors that determine the feasibility of this EAD method are revealed.

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Three isomers were prepared by covalently grafting carbazole (Cz) onto spiro[fluorene-9,9'-xanthene] (SFX) at different positions. Due to the complicated and variable roles of molecular segments, an evolution of the corresponding molecular packing mode was realized, accompanied by the change of nanocrystal morphology and photoluminescence properties.

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Rational molecular design for the organic nanocrystal morphology still remains a challenge due to the structural diversity and complicated weak intermolecular interactions. In this work, a typical attractor-repulsor molecule N,N-diphenyl-4-(9-phenyl-fluoren-9-yl) phenylamine (TPA-PF) is designed to explore a general assembly strategy for 2D nanocrystals. Via an interdigital lipid bilayer-like (ILB) molecular packing mode, large-sized lamellar 2D nanosheets are obtained with a length:width:thickness ratio as ≈2500:1000:1.

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The surface energy and surface stability of Ag nanocrystals (NCs) are under debate because the measurable values of the surface energy are very inconsistent, and the indices of the observed thermally stable surfaces are apparently in conflict. To clarify this issue, a transmission electron microscope is used to investigate these problems in situ with elaborately designed carbon-shell-capsulated Ag NCs. It is demonstrated that the {111} surfaces are still thermally stable at elevated temperatures, and the victory of the formation of {110} surfaces over {111} surfaces on the Ag NCs during sublimation is due to the special crystal geometry.

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Intramural pregnancy is a rare type of ectopic pregnancy, where the gestational sac is implanted inside the myometrium instead of the endometrial and fallopian tubes. Preoperative diagnosis remains very difficult. Ultrasonic findings vary according to the anatomical location or duration of pregnancy.

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To evaluate the feasibility of non-invasive vascular real-time elastography imaging (RTE) in visualizing the composition of rabbit carotid atherosclerotic plaque as determined by histopathology, a rabbit model of accelerated carotid atherosclerosis was used. Thirty rabbits were randomly divided into two groups of 15 rabbits each. The first group was fed a cholesterol-rich diet and received balloon-induced injury the left common carotid artery endothelium, whereas the second group only received a cholesterol-rich diet.

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The objective of this study was to investigate the feasibility of using 3-D transvaginal tomographic ultrasound imaging (TUI) to stage patients with cervical carcinoma. Eighty women with cervical cancer who underwent transvaginal TUI examinations were enrolled. In all patients, cancer was confirmed pre-operatively by pathologic examination.

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The direct in situ observation of fullerene formation encapsulated within a graphene ridge has been made possible using an aberration corrected transmission electron microscope (AC-TEM). An atom-by-atom mechanism was proposed based on in situ AC-TEM observations. First principle calculations found a continuous energy decrease upon the addition of carbon atoms to the edge of the graphene flakes, which mimics the fullerene growth steps and supports the atom-by-atom mechanism.

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Objective: Although recent evidence has implicated that 5-lipoxygenase activating protein (ALOX5AP) gene is associated with ischemic stroke (IS) risk, the underlying molecular mechanism remains to be defined. This study aimed to investigate the role of ALOX5AP rs4073259 in ischemic stroke in a Northeastern Chinese Han population.

Methods: A total of 501 IS patients and 497 healthy controls were enrolled for polymerase chain reaction (PCR) and ligase detection reaction (LDR) analysis of ALOX5AP rs4073259 single nucleotide polymorphism (SNP).

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Aim: To summarize the ultrasonic features of isolated fallopian tube torsion (IFTT) by retrospectively analyzing cases presenting at our hospital.

Methods: This analysis was approved by the ethical committee of our hospital. Medical records of surgically proven IFTT patients admitted to our hospital since 2002 were collected.

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Developments in semiconductor technology are propelling the dimensions of devices down to 10 nm, but facing great challenges in manufacture at the sub-10 nm scale. Nanotechnology can fabricate nanoribbons from two-dimensional atomic crystals, such as graphene, with widths below the 10 nm threshold, but their geometries and properties have been hard to control at this scale. Here we find that robust ultrafine molybdenum-sulfide ribbons with a uniform width of 0.

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Objective: To evaluate the clinical value of transvaginal elastography (TVES) in diagnosing cervical malignancies by detecting changes of tissue stiffness.

Methods: One hundred and ten consecutive patients with cervical lesions were enrolled. Pathological results were used as the gold standards.

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We have fabricated the flexible photoelectrode by loading graphene sheets modified with CdSe QDs. A power conversion efficiency of ∼0.6% and an incident photon to current conversion efficiency of 17% have been achieved for this flexible photovoltaic cell based on a graphene-CdSe nanocomposite.

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Taking a 2-year-old tea garden in Qingdao of Shandong Province as test object, this paper studied the effects of different mulching modes on the soil water and nutrient dynamics and tea plant growth. Four treatments were installed, i.e.

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