Publications by authors named "Li-si Huang"
Article Synopsis
- The study examines the importance of measuring BCR-ABL transcript levels in CML patients after 3 months of TKI treatment to predict their prognosis and treatment effectiveness.
- Results indicate that patients with lower BCR-ABL levels after treatment have a significantly better chance of achieving major and complete molecular responses compared to those with higher levels.
- Monitoring BCR-ABL transcripts can help adjust treatment strategies early on, potentially improving outcomes for CML patients.
Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata.
Beilstein J Org Chem
August 2012
Five carbamate derivatives, obtucarbamates C and D (1, 2), dimethyl ((carbonylbis(azanediyl))bis(2-methyl-5,1-phenylene))dicarbamate (3), obtucarbamates A and B (4, 5), and four aromadendrane-type sesquiterpenoids, (+)-4β-N-methenetauryl-10β-methoxy-1β,5α,6β,7β-aromadendrane (6), (-)-4β-N-methenetauryl-10β-methoxy-1β,5β,6α,7α-aromadendrane (7), (-)-4α,10β-aromadendranediol (8), (+)-4β,10β-aromadendranediol (9) were obtained from the South China Sea gorgonian coral Melitodes squamata Nutting. Compounds 1, 2, 6, and 7 were new, and their structures were established by spectroscopic analyses. Compounds 6 and 7 contained a taurine group that was rarely found in marine natural compounds, and 7 showed moderate antibacterial activity.
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