Discovery and Bioinspired Synthesis of Salpratone A.

Salpratone A (), a novel abietane diterpenoid containing a unique -fused A/B ring, was isolated from . Bioactivity studies showed that has potent activity in inhibiting platelet aggregation induced by multiple agonists as well as antithrombotic efficacy in the FeCl-induced rat thrombosis model. Furthermore, a bioinspired synthesis of from the abundant natural product ferruginol was achieved in 6 steps with a 22% overall yield.

11,12-seco-Abietane-type diterpene lactones with potential antiplatelet activity from Salvia prattii.

Eleven new abietane-type diterpene lactones, salpratlactones D-N (1-11), including five 11,12-seco-11-nor-abietane diterpenes (1-5), four 11,12-seco-abietane diterpenes (6-9), two 20(10 → 5)-abeo-4,5;11,12-bis-seco-abietane diterpenes (10-11), and two known analogues (12-13), were characterized from Salvia prattii. Notably, compounds 1-3 were characterized by a unique linear 6/6/6 tricyclic skeleton. The structures were established by spectroscopic data interpretation, calculated NMR-DP4+ and electronic circular dichroism analysis, as well as single-crystal X-ray diffraction.

Assimilative branches and leaves of the desert plant Alhagi sparsifolia Shap. possesses a different adaptation mechanism to shade.

Leaves and assimilative branches are crucial to the life cycle of Alhagi sparsifolia Shap. (Fabaceae), which grows in high-irradiance environments and is the main vegetation in the forelands of the Taklamakan Desert. This plant has an important role in wind protection and sand fixation at the oasis-desert transition zone.

[Photosystem II characteristics of nine Gramineae species in southern Taklamakan Desert].

Taking the Gramineae species Elytrigia intermedia, Avena sativa, Bromus inermis, Elymus sibiricus, Leymus tianschanicus, Elymus dahuricus, Festuca elata, Agropyron cristatum, and Puccinellia distans at the edge of Cele Oasis in southern Taklimakan Desert as test objects, this paper monitored their fast chlorophyll fluorescence kinetics after 20 minutes adaptation in darkness, compared their photosystem II (PS II) characteristics, and analyzed their adaptability to the local environment. Among the nine Gramineae species, L. tianschanicus and E.

[A clinical study of pelvic floor electrical stimulation in treatment of overactive bladder].

Objective: To observe the efficacy of electrical stimulation in treatment of overactive bladder (OAB).

Methods: Patients (n = 60) with overactive bladder were randomly divided into 2 groups. Electrical stimulation group (n = 35) used an instrument for electrical stimulation through a special vagina or rectum probe transfer current (8-70 mA), for 20 min, qd, for 20-30 times.