Publications by authors named "Li-qiong Hou"
Article Synopsis
- A new study investigates a more efficient and cost-effective method for mobilizing stem cells in multiple myeloma patients using high-dose cyclophosphamide (HD-Cy) along with a single injection of pegylated G-CSF (PEG G-CSF) and on-demand plerixafor (PXF), rather than daily G-CSF injections.
- The results show that the combination of HD-Cy and PEG G-CSF with or without PXF achieved significantly higher CD34 cell counts and a greater percentage of patients reached the optimal stem cell harvest compared to other treatment regimens.
- Although the new method is a bit more expensive than some alternatives, it remains more economical than other combinations while showing fewer instances of complications
High-dose cyclophosphamide (HD-Cy) (3 g/m) plus granulocyte colony-stimulating factor (G-CSF) is a very effective regimen for peripheral blood stem cell (PBSC) mobilization. Unfortunately, it is associated with an increased risk of neutropenic fever (NF). We analyzed the effect of NF on PBSC apheresis results and the efficacy of prophylactic antibiotics for the prevention of NF associated with HD-Cy plus G-CSF for PBSC mobilization in patients with newly diagnosed multiple myeloma (MM).
View Article and Find Full Text PDFTNF inhibitors have been used in ankylosing spondylitis (AS). The efficacy of TNF inhibitors was already evaluated by meta-analysis of randomized controlled trials (RCTs). However, the safety of TNF inhibitors is still unclear.
View Article and Find Full Text PDFGarlic intake lowers fasting blood glucose: meta-analysis of randomized controlled trials.
Asia Pac J Clin Nutr
April 2016
Garlic is a common spicy flavouring agent also used for certain therapeutic purposes. Garlic's effects on blood glucose have been the subject of many clinical and animal studies, however, studies reporting hypoglycemic effects of garlic in humans are conflicting. A comprehensive literature search was conducted to identify relevant trials of garlic or garlic extracts on markers of glycemic control [fasting blood glucose (FBG), postprandial glucose (PPG), glycosylated haemoglobin (HbA1c)].
View Article and Find Full Text PDF[Changes of plasma glucagon level in individuals with different glucose metabolism].
Sichuan Da Xue Xue Bao Yi Xue Ban
May 2014
Objective: To determine the levels of plasma glucagon and associated factors in individuals with different glucose metabolism.
Methods: One hundred and ten outpatient patients received an oral glucose tolerance test (OGTT) voluntarily. The patients were divided into three groups according to their OGTT results: normal glucose golerance (NGT) group (n=33), impaired glucose regulation (IGR) group (n=35), newly diagnosed type 2 diabetes (DM2) group (n=42).
[Change and correlated factors of fasting level of the plasma endotoxin in subjects with different glucose tolerances and body mass indices].
Sichuan Da Xue Xue Bao Yi Xue Ban
September 2013
Article Synopsis
- The study aimed to evaluate fasting plasma endotoxin (ET) levels and their relationship with factors like glucose tolerance and body mass index (BMI) in individuals with type 2 diabetes (T2DM), impaired glucose regulation (IGR), and normal glucose tolerance (NGT).
- Methods included measuring various health metrics and biochemical markers in different subgroups based on glucose tolerance and obesity status.
- Results showed that plasma ET levels were significantly higher in the T2DM group compared to the NGT group, with trends indicating differences in obesity but not statistically significant; the IGR group's ET levels fell in between but did not differ significantly from the others.