[Age distribution characteristics of intestinal segmented filamentous bacteria and their relationship with intestinal mucosal immunity in children].

Objective: To investigate the age distribution characteristics of intestinal segmented filamentous bacteria (SFB) in children and their relationship with intestinal mucosal immunity.

Methods: The fresh feces of 177 children and the ileocecal fluid of 47 children during colonoscopy were collected. The SFB was determined by real-time PCR.

CHADS-Vasc score and CHADS-Vasc-HS score are poor predictors of in-stent restenosis among patients with coronary drug-eluting stents.

Objective: To evaluate the ability of two scoring systems (CHADS-VASc score and CHADS-VASc+hyperlipidaemia+smoking [CHADS-VASc-HS score]) to predict in-stent restenosis (ISR) among patients undergoing drug-eluting stent (DES) implantation.

Methods: This retrospective study enrolled patients who underwent coronary angiography to assess coronary artery disease severity secondary to a diagnosis of stable angina or acute coronary syndrome that subsequently underwent DES implantations. Demographic, clinical, angiographic and biochemical parameters were compared between those patients that experienced ISR and those that did not during the study follow-up period.

Ileal perforation caused by a fish bone shortly after drug-eluting stent implantation for acute myocardial infarction.

During the past century, the incidence of myocardial infarction has markedly increased worldwide. Percutaneous coronary intervention with stent implantation is often considered as the first-choice treatment, especially in emergency cases. Current guidelines recommend delayed elective noncardiac surgery for such vulnerable patients.

Dronedarone and Amiodarone Induce Dyslipidemia and Thyroid Dysfunction in Rats.

Background/aims: Amiodarone, a thyroid hormone-like molecule, can induce dyslipidemia and thyroid dysfunction. However, the effects of dronedarone on lipid metabolism and of both dronedarone and amiodarone on thyroid function and lipid metabolism remain unknown.

Methods: Fifty male Sprague-Dawley rats were randomly divided into 5 groups (10 in each group): normal control (NC), amiodarone-treated (AMT), dronedarone-treated (DRT), rats treated with amiodarone combined with polyene phosphatidylcholine (AC), and rats treated with dronedarone combined with polyene phosphatidylcholine (DC).

[Timing of nasojejunal feeding tube placement and enteral nutrition in children with acute pancreatitis].

Objective: To investigate the impact of timing of nasojejunal feeding tube placement and enteral nutrition on clinical outcomes in children with acute pancreatitis.

Methods: A retrospective analysis was performed on the clinical data of 31 children with acute pancreatitis, who received nasojejunal feeding between January 2008 and July 2013, to investigate the relationship of abdominal symptoms/signs and serum amylase level with the tolerability of catheterization and success rate of enteral nutrition. The treatment outcome and incidence of adverse reactions and complications were compared between the early enteral nutrition group ( ≤7 days from the onset of the disease) and late enteral nutrition group (>7 days from the onset of the disease).

Highly enantioselective trapping of zwitterionic intermediates by imines.

Reactions with the unstable and highly reactive zwitterionic intermediates generated in processes catalysed by transition metals are providing new opportunities for molecular constructions. Insertion reactions involve the collapse of zwitterionic intermediates, but trapping them would allow structural elaborations that are not currently available. To synthesize complex molecules in this manner, reactive electrophiles can be used to trap the zwitterionic intermediates.

[Electrochemical therapy combined with pingyangmycin injection in the management of high-return flow venous malformation].

Objective: To investigate the clinical effect of electrochemical therapy (ECT) combined with pingyangmycin (PYM) injection for the treatment of high-return flow venous malformation.

Methods: A total of 68 cases of the high-return flow venous malformation were retrospectively analyzed, in which 32 cases received simplely ECT,and 36 cases received ECT combined with PYM injection. The patients were followed up from 6 to 30 months.

Effects of mid-myocardial pacing on transmural dispersion of repolarization and arrhythmogenesis.

Introduction: Epicardial (Epi) activation of the left ventricular (LV) wall increases transmural dispersion of repolarization (TDR), which creates a substrate for the development of ventricular arrhythmia. We hypothesize that pacing from the LV mid-myocardium may decrease the TDR and occurrence of arrhythmias.

Methods And Results: A transmural electrocardiogram and transmembrane action potentials were simultaneously recorded from Epi, mid-myocardial (M), and endocardial (Endo) layers of the arterially perfused canine LV wedge preparations (n= 8).

Diastereoselectively switchable enantioselective trapping of carbamate ammonium ylides with imines.

The diastereoselectively switchable enantioselective trapping of protic carbamate ammonium ylides with imines is reported. The intriguing Rh(2)(OAc)(4) and chiral Brønsted acid cocatalyzed three-component Mannich-type reaction of a diazo compound, a carbamate, and an imine provides rapid and efficient access to both syn- and anti-α-substituted α,β-diamino acid derivatives with a high level control of chemo-, diastereo-, and enantioselectivity.

[Refractive and biometric changes in adolescent guinea pig eyes in development and recover stages of form-deprivation myopia].

Objective: To investigate changes in refraction and vitreous length during form-deprivation and visual re-exposure in guinea pig eyes.

Methods: It was an experimental study. Ninety-six guinea pigs with age of three weeks were randomly divided into form-deprivation and normal control groups (n = 48 in each group).

[Measurement of grating acuity in guinea pigs by a customized automated optomotor device].

Objective: The guinea pig becomes an important model for studies on myopia, but little is known about its visual performance. In this study, grating acuity was measured using a custom-built automated device to track optomotor responses.

Methods: To record head nystagmus, guinea pigs were individually placed in the center of a rotating drum of 130 cm diameter.

[Susceptibility of guinea pig eyes to form deprivation myopia and its age-related recovery].

Objective: Young guinea pigs are susceptible to become myopic during form deprivation. They can also quickly recover from the myopia after removal of the form deprivation. This study investigated whether mature guinea pigs are sensitive to form deprivation and its refractive recovery from deprivation myopia.

[Form deprivation myopia in C57BL/6 mice].

Objective: To investigate the changes of refraction and ocular biometric parameters in form deprived myopia, and try to find the effective duration to induce significant myopic shift in C57BL/6 mice.

Methods: It was an experimental study. Seventy-four C57BL/6 mice, approximately 23 days old, were divided into three groups randomly: FD (Form-deprivation), Recovery and Normal control groups.

[Therapeutic effects of traditional Chinese herbal formula with Smilax glabra on mice's lead poisoning].

Objective: To investigate the influence of traditional Chinese herbal formula with Smilax glabra on lead expelling and oxidative damage in lead-poisoned mice.

Methods: Mice were received intraperitoneal injections of lead acetate to establish lead-poisoned models. The concentration of lead, zinc and copper in blood, brain, liver, kidney and bone were determined.

First record of Bursaphelenchus rainulfi on pine trees from eastern China and its phylogenetic relationship with intro-genus species.

Bursaphelenchus rainulfi isolated from dead pine trees in Zhejiang, China, is described and illustrated. It also provided some molecular characters of the Chinese population, including the PCR-RFLP and sequences of ITS region and D2-D3 expansion region of the large subunit (LSU) rRNA gene. Both the morphological characters and ITS-RFLP patterns match with the original description.

[The grating acuity of children in preschool age].

Objective: To study the developmental trend of the binocular grating acuity of preschool children.

Methods: Binocular grating acuities in 599 children from 2 months to 72 months old (18 groups) were measured using the closed-circuit operant preferential looking system (COPLs). The children included in the investigation were required to be a normal term birth, development and normal eyes, and cycloplegic refraction error within specific limits.