Publications by authors named "Li-ping Lei"

Introduction: Early diagnosis of Parkinson's disease (PD) remains challenging. It has been suggested that abnormal brain iron metabolism leads to excessive iron accumulation in PD, although the mechanism of iron deposition is not yet fully understood. Ferritin and transferrin receptor (TfR) are involved in iron metabolism, and the exosome pathway is one mechanism by which ferritin is transported and regulated.

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  • Modified Child-Pugh (MCP) and Albumin-bilirubin (ALBI) grades are simpler and more objective alternatives to the traditional Child-Pugh (CP) class for evaluating liver function in patients with Hepatocellular Carcinoma (HCC).
  • A study involving 376 HCC patients treated with transcatheter arterial chemoembolization (TACE) showed that the MCP grade had a higher predictive accuracy for overall survival compared to both CP and ALBI grades.
  • While most patients presented with CP class A disease, the MCP grade was able to identify three distinct prognostic groups, indicating that it may be a more effective stratification tool than the CP class or ALBI grade for these patients.
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  • The complete genome sequence of the bacterial strain LLRS-1, which causes bacterial wilt in flue-cured tobacco, is presented for the first time in China.
  • This strain has a total genome size of approximately 5.7 million base pairs, consisting of a circular chromosome and a megaplasmid.
  • The genome includes a diverse set of genetic elements, featuring over 5,190 protein-coding genes and various types of RNA, demonstrating its genetic complexity.
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Background: Midkine (MK), a heparin-binding protein, participates in multiple cellular processes, such as immunity, cellular growth and apoptosis. Overwhelming evidence indicates that MK plays an important role in various pathological processes, including chronic inflammation, autoimmunity, cancer, and infection. Recent studies demonstrated that MK may be involved in the development of atherosclerosis, yet the mechanism has not been fully explored.

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Objective: To observe the effect of electroacupuncture (EA) on changes of ultrastructure of oligodendrocytes in the marginal zone of the cerebral ischemia (CI) locus in rats with cerebral infarction so as to reveal its mechanism underlying improving ischemic cerebral diseases.

Methods: Ninety male SD rats were randomized into sham operation, model and electroacupuncture (EA) groups which were further divided into five subgroups: 1 h, 1 d, 3 d, 7 d, and 21 d after CI (n = 6 in each subgroup). The CI model was established by occlusion of the middle cerebral artery.

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Atmospheric CO2 column concentration (column-averaged dry air mole fractions of atmospheric carbon dioxide) data obtained by ground-based hyperspectral observation is an important source of data for the verification and improvement of the results of CO2 retrieval based on satellite hyperspectral observation. However, few studies have been conducted on atmospheric CO2 column concentration retrieval based on ground-based spectral hyperspectral observation in China. In the present study, we carried out the ground-based hyperspectral observation in Xilingol Grassland, Inner Mongolia of China by using an observation system which is consisted of an optical spectral analyzer, a sun tracker, and some other elements.

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A fungal strain named YLF-14 was isolated from the leaf of Altingia yunnunensis. Based on the sequence at the internal transcribed spacer (ITS) region, the strain was identified as an Aspergillus sp..

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New heteroleptic iridium(III) complexes (ppz)2Ir(LX), which consist of two cyclometalated ligands ppz(1-phenylpyrazole) together with an ancillary ligand LX (LX= 2-(2'-hydroxylphenyl)benzothiazole (BTZ), 2-(3'-methyl-2'-hydroxylphenyl) benzothiazole (3-MeBTZ), 2-(4'-methyl-2'-hydroxylphenyl) benzothiazole (4-MeBTZ) and 2-(4'-Trifluoromethyl-2'hydroxylphenyl) benzothiazole (4-tfmBTZ)), were synthesized and characterized. The molecular structures and photophysical properties were characterized and analyzed comparatively. The results show that the four complexes have basically similar UV-Vis absorption spectra, fluorescence excitation and emission spectra.

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The implantation of intravascular stents has become a new method to cure stenosis in arteries with its low injury and high efficiency. The mechanical behavior of the stents is studied by the finite element method. The compression behavior is simulated with stent models of different sizes and geometry structures whose material is cobalt-chromium alloy.

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  • - The study focused on obtaining and characterizing the recombinant protein from the Ts88 antigen gene of Trichinella spiralis by expressing it in E. coli.
  • - Mice immunized with the resulting fusion protein produced high levels of antibodies, indicating the protein's ability to trigger an immune response, as confirmed by ELISA and Western blotting tests.
  • - The results revealed that the Ts88 recombinant protein was recognized by antibodies from various infected sources, and an immuno-fluorescence test showed it localized primarily on the worm's cuticle surface.
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