Customization of Protein Single Nanowires for Optical Biosensing.

An all-protein single-nanowire optical biosensor is constructed by a facile and general femtosecond laser direct writing approach with nanoscale structural customization. As-formed protein single nanowires show excellent optical properties (fine waveguiding performance and bio-applicable transmission windows), and are utilized as evanescent optical nanobiosensors for label-free biotin detection.

Subwavelength focusing by a micro/nanofiber array.

Utilizing the diffraction property of the output light from micro/nano fibers (MNFs), a new scheme based on a MNF array to focus optical beams with subwavelength resolution in the far field is proposed. By using the three-dimensional finite-difference beam-propagation method (FD-BPM), we investigated the diffraction interference effect of the MNFs during light propagation. The numerical stimulation demonstrates a focusing spot with FWHM of 0.

All-fiber Fabry-Perot resonators based on microfiber Sagnac loop mirrors.

We demonstrate all fiber Fabry-Perot resonators (F-P resonators) based on Sagnac loop mirrors assembled with tellurite microfibers. As-assembled F-P resonators, with dimensions of hundreds of micrometers, show clear resonant responses with typical quality factor of about 5700, free spectral range of about 1 nm, and a maximum extinction ratio of 18 dB. The reflectivity of the loop mirror and the effective cavity length of the F-P resonator can be tuned by micromanipulation under an optical microscope.

Compact optical short-pass filters based on microfibers.

We demonstrate a compact short-pass filter fabricated by integrating a microfiber (approximately 1 microm in diameter) with a low-index substrate. By varying the interaction length (from 0.65 to 3 mm) between the microfiber and the substrate for wavelength-dependent evanescent leakage, the cutoff wavelength has been tuned over a wide range of 400 nm.

Modeling endface output patterns of optical micro/nanofibers.

Endface output patterns of micro/nanofibers (MNFs) are simulated using a Three-Dimension Finite-Difference Time-Domain (3D-FDTD) method. The intensity distribution and beam widths of near- or farfield output patterns of freestanding silica and tellurite MNFs with flat, angled, spherical and tapered endfaces in air and/or water are obtained. It shows that, for a subwavelength-diameter MNF, highly confined output beam can be obtained in the near field, and the beam width can be tuned by the ratio of fiber diameter and light wavelength with a minimum width smaller than the wavelength.

The effect of hepatic blood inflow occlusion on hepatic cancer treated with diode-laser thermocoagulation.

Objective: To assess the effect of temporary occlusion of hepatic blood inflow on hepatic cancer treated with diode-laser induced thermocogation (LITT).

Methods: The carcinoma Walker-256 was implanted in 40 SD rat livers. Twelve days later, the animals were randomly divided into 4 groups.

[Experimental study of diode-laser induced thermocoagulation on hepatic tissue with scanner fiber tip].

Objective: To seek a safe, efficient, and cost-effective technique for local thermo-ablation of hepatic cancer.

Methods: The livers from 16 healthy rabbits were thermocoagulated by diode-laser with scanner fiber tip, 6 w for 10 mins. At the same time, the temperatures were measured at 0, 5 and 10 mm from laser tip.

Experimental study of diode-laser induced thermocoagulation on hepatic tissue with scanner fiber tip.

Aim: To explore a safe, efficient, and cost-effective technique for local thermo-ablation of hepatic tumors.

Methods: The livers of 16 healthy rabbits were thermocoagulated by diode-laser with a hand-made scanner fiber tip, 6 w for 10 min. At the same time, the temperature was measured at 5 and 10 mm from the laser tip.