Efficacy and safety of sirolimus early conversion protocol in liver transplant patients with hepatocellular carcinoma: A single-arm, multicenter, prospective study.

Mammalian target of rapamycin (mTOR) inhibitor as an attractive drug target with promising antitumor effects has been widely investigated. High quality clinical trial has been conducted in liver transplant (LT) recipients in Western countries. However, the pertinent studies in Eastern world are paucity.

Three new taxoids from the seed of Taxus cuspidata.

Three new taxoids (1-3), along with three known taxoids (4-6), were isolated from a EtOAc extract of Taxus cuspidata seed. The structures of 1-3 were determined by analyses of spectroscopic data.

[A cross-sectional case study of human immunodeficiency virus and tuberculosis co-infection in mainland China].

Objective: In order to take an insight into the profile of HIV/AIDS and tuberculosis (TB) co-infection, we made a statistic survey in 9 hospitals in mainland China. With the purpose of guiding the prevention and treatment, 241 cases with such co-infection were enrolled and the data with respect to clinical manifestations, laboratory tests, therapy and prognosis were analysed.

Methods: All indices were collected with unified questionary.

[Coinfection with HBV and HCV in 128 AIDS patients infected through blood transmission].

Objective: To analyze the clinical features of 128 acquired immunodeficiency syndrome (AIDS) patients infected through blood transmission who were coinfected with hepatitis B virus (HBV) and hepatitis C virus (HCV).

Methods: The prevalence, liver functions, and some immunological profiles of 128 AIDS patients coinfected with HBV and HCV were retrospectively analyzed.

Results: Among the 128 AIDS patients, 107 (83.