Simple and effective method for treating severe adult skeletal class II malocclusion: A case report.

Background: Severe skeletal class II malocclusion is the indication for combined orthodontic and orthognathic treatment.

Case Summary: A woman with a chief complaint of a protruding chin and an inability to close her lips requested orthodontic camouflage. The treatment plan consisted of extracting the right upper third molar, right lower third molar, left lower second molar, and left upper third molar and moving the maxillary dentition distally using a convenient method involving microimplant nail anchors, push springs, long arm traction hooks, and elastic traction chains.

Effect of tDCS combined with virtual reality for post-stroke cognitive impairment: a randomized controlled trial study protocol.

Background: Post-stroke cognitive impairment (PSCI) not only increases patient mortality and disability, but also adversely affects motor function and the ability to perform routine daily activities. Current therapeutic approaches for, PSCI lack specificity, primarily relying on and medication and traditional cognitive therapy supplemented by a limited array of tools. Both transcranial direct current stimulation (tDCS) and virtual reality (VR) training have demonstrated efficacy in improving cognitive performance among PSCI patients.

Theory of mind and facial emotion recognition in adults with temporal lobe epilepsy: A meta-analysis.

Background: Mounting studies have investigated impairments in social cognitive domains (including theory of mind [ToM] and facial emotion recognition [FER] in adult patients with temporal lobe epilepsy (TLE). However, to date, inconsistent findings remain.

Methods: A search of PubMed, Web of Science, and Embase databases was conducted until December 2021.

Social cognition in children and adolescents with epilepsy: A meta-analysis.

Many studies have investigated impairments in two key domains of social cognition (theory of mind [ToM] and facial emotion recognition [FER]) in children and adolescents with epilepsy. However, inconsistent conclusions were found. Our objective was to characterize social cognition performance of children and adolescents with epilepsy.

[Electroacupuncture at "Zusanli"(ST36) protects intestinal mucosal immune barrier by suppre-ssing apoptosis of intestinal lymphocytes and regulating expression of Bcl-2 and Bax in sepsis rats].

Objective: To observe the effect of electroacupuncture (EA) at "Zusanli" (ST36) on apoptosis of intestinal T lymphocytes, translocation of intestinal bacteria and expression of intestinal Bcl-2 and Bax proteins and intestinal mucosal immune barrier in sepsis rats, so as to explore its underlying mechanism in relieving sepsis.

Methods: SD rats were randomly divided into sham operation (=6), model (=15), non-meridian and non-acupoint (non-acupoint, =15) and acupoint EA(=15) groups by using random number table method. The sepsis model was established by using cecal ligation and perforation(CLP) method.

[Incidence and risk factors of temporomandibular joint disorders in patients with bimaxillary protrusion after orthodontic treatment].

Purpose: To observe the occurrence of temporomandibular joint disorder (TMD) in patients with bimaxillary protrusion after orthodontic treatment, and to explore the possible factors causing this phenomenon, so as to guide rational prevention of TMD in clinic.

Methods: The clinical data of 80 patients with bimaxillary protrusion who received orthodontic treatment in Hebei Provincial People's Hospital from March 2019 to October 2020 were retrospectively analyzed. The patients with TMD after orthodontic treatment were included in the experimental group and the remaining patients were included in control group.

A meta-analysis of the association between preoperative magnetic resonance imaging and surgical outcomes in newly diagnosed breast cancer.

Introduction: The use of preoperative magnetic resonance imaging (MRI) in newly diagnosed breast cancer has been increasing. However, the value of MRI applied to women with newly diagnosed breast cancer remains controversial. Therefore, this study focused on the association between preoperative MRI and surgical outcomes, which include mastectomy rate, breast conservation rate, and re-excision rate.

The role of peripheral type 2 innate lymphoid cells in bronchiolitis.

Our aim was to detect type 2 innate lymphoid cells (ILC2s)-related cytokines of infants with bronchiolitis by using Elisa, Liquidchip technology and RT-PCR and investigated its correlation with bronchiolitis. We recruited 26 infants with bronchiolitis and 20 healthy infants as control from Xiangya Hospital. Compared to the control group, the serum levels of interleukin-5 (IL-5) [41.

Promotes Malignant Progression of Glioma by Targeting miR-140-5p and Regulating PI3K/AKT Pathway.

Purpose: To explore the regulatory mechanism of long non-coding RNA small nucleolar RNA host gene 1 (SNHG1) in glioma.

Materials And Methods: The expression of SNHG1 and miR-140-5p in glioma tissues and glioma cell lines (LN-18, KNS-81, and KALS-1) was determined, and the effect of the two on cell proliferation, invasion, and PI3K/AKT pathway was analyzed.

Results: SNHG1 was overexpressed in glioma tissues, while miR-140-5p was underexpressed in them, and there was a significant negative correlation between SNHG1 and miR-140-5p.

Cul4B promotes the progression of ovarian cancer by upregulating the expression of CDK2 and CyclinD1.

Background: Ovarian cancer is one of the most common malignant tumors in the female reproductive system with the highest mortality rate. Cul4B participates in the oncogenesis and progression of several malignant tumors. However, the role of Cul4B in ovarian cancer has not been studied.

[Effects of basic periodontal treatment on endothelin, vascular endothelial growth factor-A and tumor necrosis factor-α levels in gingival crevicular fluid and serum].

Purpose: To investigate the effects of basic periodontal treatment on the levels of endothelin (ET), vascular endothelial growth factor-A (VEGF-A) and tumor necrosis factor-α (TNF-α) in gingival crevicular fluid and serum.

Methods: A total of 57 patients with periodontitis (experimental group) and 43 healthy examinees (control group) admitted to Shenzhen Hospital of Guangzhou University of Chinese Medicine from October to May 2018 were selected. Patients received subgingival scaling and root planing for 6 weeks.

Cyclin-dependent kinase 4/6 inhibitor in combination with endocrine therapy versus endocrine therapy only for advanced breast cancer: a systematic review and meta-analysis.

Background: The resistance to endocrine therapy poses a significant challenge to the management of advanced breast cancer with hormone receptor (HR) positive and human epidermal growth factor receptor 2 (Her-2) negative. The purpose of this study was to further examine the efficacy and safety of cyclin-dependent kinase 4/6 inhibitors (CDK4/6Is) in combination with endocrine therapy as a recovery treatment for advanced breast cancer patients.

Methods: The risk of bias for each included study was assessed using the Cochrane Risk of Bias Tool.

Serum Gamma-glutamyl Transferase Levels Predict Functional Outcomes after Aneurysmal Subarachnoid Hemorrhage.

Objective: We aim to explore the potential association between serum gamma-glutamyl transferase levels and functional outcome after aneurysmal subarachnoid hemorrhage in a Chinese population.

Methods: A total of 386 aneurysmal subarachnoid hemorrhage patients were included in the study from September 2007 to February 2015. Baseline serum gamma-glutamyl transferase levels and 6-month follow-up functional outcomes were determined.

Epigenetic priming with decitabine followed by low-dose idarubicin/cytarabine has an increased anti-leukemic effect compared to traditional chemotherapy in high-risk myeloid neoplasms.

Decitabine (DAC) is commonly used for the treatment of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Previous studies have indicated DAC sequentially combined with idarubicin was an effective treatment for myeloid neoplasms. Therefore, a clinical study was conducted of the sequential combination of DAC followed by low-dose idarubicin/cytarabine in high-risk myeloid neoplasms.

Ferrocenylethynyl-terminated azobenzenes: synthesis, electrochemical, and photoisomerization studies.

Ferrocenylethynyl-terminated derivatives 8-12 have been synthesized and characterized by electrochemistry and UV/Vis spectroscopy. The electrochemical and photophysical studies indicate that the electronic communication in ferrocenylethynyl-substituted derivatives is strongly influenced by the substituted position of the ferrocenylethynyl moiety. In situ electrochemical oxidation or chemical oxidation caused a characteristically weak ligand-to-metal charge-transfer (LMCT) band to appear at 700-1000 nm.

Ruthenium(II) bis(terpyridine) electron transfer complexes with alkynyl-ferrocenyl bridges: synthesis, structures, and electrochemical and spectroscopic studies.

Two novel alkynyl-bridged symmetric bis-tridentate ligands 1,2-bis(1'-[4'-(2,2':6',2''-terpyridinyl)]ferrocenyl)ethyne (3a; tpy-Fc-C[triple bond]C-Fc-tpy; Fc = ferrocenyl; tpy = terpyridyl) and 1,4-bis(1'-[4'-(2,2':6',2''-terpyridinyl)]ferrocenyl)-1,3-butadiyne (3b; tpy-Fc-C[triple bond]C-C[triple bond]C-Fc-tpy) and their Ru(2+) complexes 6a and 6b have been synthesized and characterized by cyclic voltammetry, UV-vis and luminescence spectroscopy, and in the case of 3b by single-crystal X-ray diffraction. Cyclic voltammograms of both compounds, 3a and 3b, display two severely overlapping ferrocene-based oxidative peaks with only one reductive peak. The redox behavior of 6a and 6b is dominated by the Ru(2+)/Ru(3+) redox couple (E(1/2) from 1.

[Analysis of light scatter changes and relevant factors after laser refractive surgery].

Objective: To investigate the changes and relevant factors of forward scatter after Epipolis laser in situ keratomileusis (Epi-LASIK)and laser in situ keratomileusis (LASIK).

Methods: It was a prospective clinical comparative study. 45 patients (45 eyes) were scheduled for Epi-LASIK and 42 patients (42 eyes) for LASIK.