Objective: This study aims to explore the therapeutic potential of mesenchymal stem cells (MSC) in treating diabetic nephropathy (DN) by investigating their effect on IL-11 modulation in a mouse model.
Methods: The effects of MSC therapy on DN were examined both in vivo and in vitro. Sixty adult male C57BL/6 mice were divided into the streptozotocin (STZ) diabetes (T1D) and the high-fat diet diabetes (T2D) models, with both groups receiving MSC treatment or saline for 4 or 8 weeks.
Zhongguo Dang Dai Er Ke Za Zhi
September 2019
Objective: To investigate the serum level of soluble transferrin receptor (sTfR) and its association with the degree of anemia in children with hemoglobin H (HbH) disease.
Methods: A total of 55 children with HbH disease were enrolled as the HbH group, and 30 healthy children were enrolled as the control group. The HbH group was further divided into a deletional HbH disease group and a non-deletional HbH disease group.
The striking rise of methicillin-resistant (MRSA) infections has become a serious threat to public health worldwide. In an effort to search for new anti-MRSA agents from natural products, a bioassay-guided phytochemical study was conducted on the semi-mangrove plant A. Gray, which led to the isolation of two new sesquiterpene alkaloids ( and ) and six known furanosesquiterpenes (⁻).
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
April 2015
Objective: To explore an economical and efficient molluscicidal method suitable for large area of nursery stock field.
Methods: Two nursery stock fields with Oncomelania hupensis were selected as experimental sites, and an experimental group and a control group were set. In the experimental group, the molluscacide and herbicide were alternately used (a purification molluscicidal method) during the period of May to October, 2011.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
February 2015
Objective: To evaluate the molluscicidal effect of black plastic film combined with carbon amide.
Methods: In Jiangdong Town, Jinhua City, the field with Oncomelania hupensis in the history was selected as experimental area and divided into 3 groups: Group One was administered with black plastic film combined with carbon amide; Group Two was administered with simple black plastic film; and Group Three was a control group.
Results: On the 3rd, 7th, 15th, 20th and 30th day after the experiment, the mortality rates of 0.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
June 2014
Objective: To explore a high molluscicidal efficient method in special Oncomelania hupensis snail environments.
Methods: In 2005 and 2006, in large special environments (rubble creek beaches and seepage barren hills with snails), the mechanical soil-buried method (excavator digging to bury deep snails) and manual soil-buried method were used respectively, and the results were compared for the cost-effectiveness.
Results: With the mechanical soil-buried method in 2006, the investment was 0.