Publications by authors named "Li-jun Feng"

Liver cancer is associated with a few factors, such as viruses and alcohol consumption, and hepatectomy is an important treatment for patients with liver cancer. However, post-hepatectomy liver failure (PHLF) is the most serious complication and has a high mortality rate. Effective prediction of PHLF allows for the adjustment of clinical treatment strategies and is critical to the long-term prognosis of patients.

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Central Zhejiang is the key ecological function area of Zhejiang Province and an important part of the Qiantang River ecological corridor. Conducting simulations of ecosystem carbon storage changes and analyzing influencing factors under land-use changes in this region is of significant importance for achieving the goals of "peak carbon" and "carbon neutrality" at an early stage. This study, based on the land use data of five periods from 1980 to 2020 in central Zhejiang, coupled the GeoSOS-FLUS and the InVEST model to analyze the spatiotemporal changes in carbon storage in the region over time and project for the year 2030.

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  • Osteosarcoma is a malignant bone tumor primarily affecting children and adolescents, particularly in fast-growing areas like the knees and arms; this study examines the trends in osteosarcoma metabolomics research over the last decade.
  • A bibliometric analysis was conducted using data from the Web of Science Core Collection from 2014 to 2023, utilizing visualization tools to assess trends, major contributors, and key research themes.
  • Shanghai Jiao Tong University published the most papers, with China leading in overall contributions to the field, while the keyword "expression" emerged as the most focused topic among the research clusters identified.
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Objectives: To observe the effects of electroacupuncture (EA) stimulation of "Sishencong"(EX-HN1) and "Fengchi"(GB20) on lactate (Lac) content, expression of proline hydroxylase 2 (PHD2), hypoxia-inducible factor-1α (HIF-1α)/nuclear transcription factor- κB (NF- κB)/NOD-like receptor thermoprotein structural domain-associated protein 3 (NLRP3) signaling pathway, and inflammatory factors in hippocampal tissue of vascular dementia (VD) rats, so as to explore its mechanisms underlying improvement of VD.

Methods: Male SD rats screened by Morris water maze tests were randomly divided into blank control, sham-operation, VD model and EA groups (12 rats in each group). The VD model was replicated using the 4-vessel occlusion (VO) method.

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A composite wetland (CECW) was constructed by introducing P-adsorption filler (EPAF) and activated sludge into traditional wetlands for treating actual sewage. The results showed that EPAF improved P removal through physico-chemical adsorption, and it could be stably regenerated after adsorption saturation without potential risks. Meanwhile, zeolite promoted NH-N reduction in sewage by cation exchange.

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The 24 solar terms are a significant component of traditional Chinese culture. Amid global warming climate change, research on the Solar Terms has gained increasing prominence. Identifying the geographical origins of the Solar Terms not only provides evidence for studies on the origins of Chinese agricultural civilization but also serves as a critical foundation for the innovative utilization of traditional culture in the modern era.

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Endochondral ossification is the process by which cartilage is mineralized into bone, and is essential for the development of long bones. Osteocalcin (OCN), a protein abundant in bone matrix, also exhibits high expression in chondrocytes, especially hypertrophic chondrocytes, while its role in endochondral ossification remains unclear. Utilizing a new CRISPR/Cas9-mediated deficiency (OCN) mouse model generated in our laboratory, we provide the first evidence of OCN's regulatory function in chondrocyte differentiation and endochondral ossification.

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  • A study was conducted to evaluate the effectiveness of "He Tiao Du Ren An Shen Acupuncture" (HTDRAS Acupuncture) in treating restless leg syndrome (RLS) compared to conventional acupuncture.
  • The study involved 66 RLS patients divided into two groups, with one receiving HTDRAS acupuncture and the other receiving standard acupuncture over a month of treatment.
  • Results showed that the HTDRAS acupuncture group had significantly better outcomes, including higher levels of serotonin and lower scores on anxiety and RLS symptom assessments, suggesting it is a safe and effective treatment option for RLS.
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Background: Percutaneous kyphoplasty (PKP) is a pivotal intervention for osteoporotic fractures, pathological vertebral compression fractures, and vertebral bone tumors. Despite its efficacy, the procedure presents challenges, notably complications arising from intradural cement leakage. Timely and accurate diagnosis, coupled with emergent intervention is imperative to improve patient prognosis.

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  • Portal vein thrombosis (PVT) is a frequent complication following splenectomy in patients with cirrhosis, but the factors that predict its occurrence are not well understood.
  • A study involving 45 patients who underwent splenectomy identified that a portal vein diameter (PVD) of ≥ 14.5 mm and a MELD score greater than 10 are significant predictors of PVT at 1, 3, and 12 months post-surgery.
  • The research showed a cumulative incidence of PVT increasing over time, with notable differences based on MELD scores and PVD measurements, suggesting closer monitoring for patients with these risk factors.
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Gut microbiome is integral to the pathogenesis of ulcerative colitis. A novel probiotic Lactobacillus intestinalis (L. intestinalis) exerts a protective effect against dextran sodium sulfate-induced colitis in mice.

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Background: The discovery of regulatory cell death has led to a breakthrough in the therapeutic field. Various forms of cell death, such as necrosis, apoptosis, pyroptosis, autophagy, and ferroptosis, play an important role in the development of liver diseases. In general, more than one form of cell death pathways is responsible for the disease state.

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  • The study examined how normal TSH levels impact survival rates in patients who experienced acute myocardial infarction (AMI) and underwent percutaneous coronary intervention (PCI).
  • Researchers enrolled 1240 patients and found that those with higher TSH levels had an increased risk of death, particularly after adjusting for other factors.
  • The findings suggest that TSH levels can enhance the predictive accuracy of mortality risk when combined with existing scoring systems, particularly for high-risk patients following AMI.
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This work evaluated the dynamic changes of phyllosphere microbiota and chemical parameters at various growth stages of Pennisetum giganteum and their effects on the bacterial community, cooccurrence networks, and functional properties during anaerobic fermentation. was collected at two growth stages (early vegetative stage [P and late vegetative stage [P]) and was naturally fermented (NP and NP) for 1, 3, 7, 15, 30, and 60 days, respectively. At each time point, NP or NP was randomly sampled for the analysis of chemical composition, fermentation parameter, and microbial number.

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The seasonal surplus and putrefactive property of moist forages inevitably increase the pressure on environmental protection and residual grass disposal. In the current work, the anaerobic fermentation approach was adopted to assist the sustainable recycling of leftover Pennisetum giganteum (LP), and its chemical composition, fermentation performance, bacterial community and functional profiles during anaerobic fermentation were studied. Fresh LP was spontaneously fermented for up to 60 d.

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  • Sepsis, triggered by an infection, can lead to long-term cognitive issues and depression, and this study focuses on whether exposure to a specific type of infection in adolescence affects mental health later in life.
  • Researchers used an LPS model to simulate bacterial infection and evaluated how it impacted stress and anxiety behaviors in adult mice after their early exposure.
  • Findings revealed that early inflammation from LPS led to heightened stress vulnerability in adulthood, but activating a specific brain signaling pathway (Nrf2-BDNF) could help reduce these negative effects.
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How to combine regional ecological risks and local ecological needs to construct ecological security is one of the main issues of its application in territorial spatial governance and associated with whether it can be effectively applied. Based on the "source" accessibility and the quality of space, we constructed the ecological security pattern of Xianyang City through the way of source-corridor-node. During the construction processes, we combined the cha-racteristics of topography, influencing factors of regional ecological security, and landscape characteristics.

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Few studies have compared the association between dosing of spironolactone and outcomes in patients with heart failure with preserved ejection fraction (HFpEF), and whether spironolactone dose could significantly affect the prognosis of HFpEF patients combined with chronic kidney disease (CKD) remains unclear. Our aim was to directly compare 'high vs. low' doses of spironolactone in an attempt to find a benefit-risk-balanced point, and infer an adequate dose for HFpEF with CKD patients.

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The present study aimed to evaluate the effects of delayed harvest and storage length on fermentation products, bacterial community, and metabolic shifts of elephant grass silage. The late-harvested elephant grass (LG) was naturally fermented (NLG) for 1, 3, 7, 15, 30, and 60 days, respectively. After 60-day ensiling, NLG displayed homolactic fermentation with low pH value, butyric acid, and ammonia nitrogen concentrations, and high lactic acid concentration, and ratio of lactic acid to acetic acid.

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The efficient storage of materials before bioethanol production could be key to improving pretreatment protocol and facilitating biodegradation, in turn improving the cost-effectiveness of biomass utilization. Biological inoculants were investigated for their effects on ensiling performance, biodegradability of silage materials, and final bioethanol yield from sweet sorghum. Two cellulolytic microbial consortia (CF and PY) were used to inoculate silages of sweet sorghum, with and without combined lactic acid bacteria (Xa), for up to 60 days of ensiling.

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The purpose of this study was to evaluate the fermentation quality, microbial community, and functional shifts of sweet sorghum during ensiling. The high-moisture sweet sorghum (SS) was naturally ensiled for 1, 3, 7, 15, 30, and 60 days. After 60 days of ensiling, sweet sorghum silage (SSS) showed homolactic fermentation with absent butyric acid, low pH value, acceptable concentrations of propionic acid, ethanol, and ammonia nitrogen and high lactic acid concentration.

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Three new luminescent metal-organic frameworks (LMOFs), [Zn(tppa)(ndc)] (1), [Cd(tppa)(oba)] (2), [Zn(tppa)(bpdc)] (3) (tppa = tri(4-pyridylphenyl)amine, ndc = 1,4-naphthalenedicarboxylic acid, oba = 4,4'-oxydibenzoic acid, bpdc = 4,4'-biphenyldicarboxylic acid) have been synthesized by solvothermal method. Complexes 1 and 2 are 2-D two-fold interpenetrating structures, aligning into a 3-D structure through C-H⋯π stacking interactions, while 3 is a 5-fold interpenetrating three-dimensional structure. The internal quantum yields (IQYs) of complexes 1-3 are 32.

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Background: Primary blast lung injury (PBLI) is a major cause of death in military conflict and terrorist attacks on civilian populations. However, the mechanisms of PBLI are not well understood, and a standardized animal model is urgently needed. This study aimed to establish an animal model of PBLI for laboratory study.

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Objective: To investigate the effect of computer navigation gap balance technology on the recovery of lower limb function after total knee arthroplasty.

Methods: The clinical data of 106 patients with knee osteoarthritis (OA) who underwent total knee arthroplasty from July 2018 to June 2019 were analyzed retrospectively. They were divided into measurement osteotomy group and space balance group according to different osteotomy techniques during total knee arthroplasty.

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Objective: This study aims to explore the factors influencing the renal glucose threshold (RT) in patients with newly diagnosed type 2 diabetes mellitus (T2DM).

Methods: A cross-sectional study was conducted on 1009 hospitalized patients with T2DM using stratified random sampling. Blood glucose was monitored using a dynamic blood glucose monitor to obtain the mean blood glucose (MBG), which is used to calculate the RT.

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