Multifunctional structures with excellent wave-absorbing and load-bearing properties have attracted much attention in recent years. Unlike other wave-absorbing materials, honeycomb wave-absorbing materials have appealing radar absorption and mechanical properties. However, the existing honeycomb wave-absorbing materials have problems such as narrow absorption band and poor compression resistance.
View Article and Find Full Text PDFThe fibrogenic conversion of satellite cells contributes to the atrophy and fibrosis of skeletal muscle, playing a significant role in the pathogenesis of age-related sarcopenia. Melatonin, a hormone secreted by the pineal gland, exhibits anti-aging and anti-fibrotic effects in various conditions. However, the effect of melatonin on satellite cell fate and age-related sarcopenia remains under-explored.
View Article and Find Full Text PDFSkeletal muscle atrophy, characterized by loss of muscle mass and function, is often linked to systemic inflammation. Tanshinone IIA (Tan IIA), a major active constituent of Salvia miltiorrhiza, has anti-inflammatory and antioxidant properties. However, the effect of Tan IIA on inflammation-induced skeletal muscle atrophy remains unclear.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
December 2024
Type H vessels have been proven to couple angiogenesis and osteogenesis. The decline of type H vessels contributes to bone loss in the aging process. Aging is accompanied by the accumulation of advanced oxidation protein products (AOPPs).
View Article and Find Full Text PDFRetraction of 'Development of EGFR-targeted evodiamine nanoparticles for the treatment of colorectal cancer' by Chunpu Li , , 2019, , 3627-3639, https://doi.org/10.1039/C9BM00613C.
View Article and Find Full Text PDFHyperalgesia is typified by reduced pain thresholds and heightened responses to painful stimuli, with a notable prevalence in menopausal women, but the underlying mechanisms are far from understood. β-Aminoisobutyric acid (BAIBA), a product of valine and thymine catabolism, has been reported to be a novel ligand of the Mas-related G protein coupled receptor D (MrgprD), which mediates pain and hyperalgesia. Here, we established a hyperalgesia model in 8-week-old female mice through ovariectomy (OVX).
View Article and Find Full Text PDFBackground: The beet armyworm, (Hübner), is an important agricultural pest worldwide that has caused serious economic losses in the main crop-producing areas of China. To effectively monitor and control this pest, it is crucial to investigate its population dynamics and seasonal migration patterns in northern China.
Methods: In this study, we monitored the population dynamics of using sex pheromone traps in Shenyang, Liaoning Province from 2012 to 2022, combining these data with amigration trajectory simulation approach and synoptic weather analysis.
Excessive angiogenesis in subchondral bone is a pathological feature of osteoarthritis (OA). Tanshinone IIA (TIIA), an active compound found in Salvia miltiorrhiza, demonstrates significant anti-angiogenic properties. However, the effect of TIIA on abnormal subchondral angiogenesis in OA is still unclear.
View Article and Find Full Text PDFTo accurately understand the biological pollution level and toxicity of polydisperse nanoplastics, an effective solution is presented to separate polydisperse nanoplastics and detect their size, mass and number concentration in a biological matrix by asymmetrical flow field fractionation coupled with a diode array detector and a multiangle light scattering detector.
View Article and Find Full Text PDFThe trichomes of Arabidopsis thaliana serve as accumulation sites for heavy metals such as Cd, and thereby both help plants cope with heavy metal stress and detoxify the soil. These trichomes are also believed to prime plant defenses against insect herbivores in response to mechanical stimulation. Because Cd in such trichomes may be beneficial for plant defenses, we hypothesized that mechanical stimulation would enhance sequestration of Cd in trichomes.
View Article and Find Full Text PDFBackground And Objectives: Human milk fat globule membrane (MFGM) has multifunctional health benefits. We evaluated neurodevelopment and growth of healthy term infants fed bovine milk-derived MFGM-enriched formula (MF) over 12 months.
Methods And Study Design: A prospective, multi-center, double-blind, randomized trial was conducted in Fuzhou, China.
Sequestration of heavy metals by plants in non-glandular leaf trichomes is important for survival in toxic soils and has the potential for environmental remediation. Although heavy metals are particularly toxic to many plants during development, the integration of sequestration into the developmental timecourse is unknown. We tested the hypothesis that plants preferentially sequester heavy metals into mature trichomes by investigating the timecourse of Cd ions into the leaves of the model plant .
View Article and Find Full Text PDFObjective: The present study investigated how mild moxibustion treatment affects the intestinal microbiome and expression of NLRP3-related immune factors in a rat model of intestinal mucositis (IM) induced with 5-fluorouracil (5-Fu).
Methods: Forty male Sprague-Dawley rats were randomly divided into control, chemotherapy, moxibustion and probiotics groups. The IM rat model was established by intraperitoneal injection of 5-Fu.
Invasion and metastasis of colorectal cancer (CRC) are leading causes of death of CRC patients. Previous findings demonstrate that evodiamine (Evo), an indolequinone alkaloid, is effective in combating CRC; however, its poor aqueous solubility and low oral bioavailability limit its application in the prevention of invasion and metastasis of CRC. It is known that selectively targeting cancer-specific receptors highly expressed on the surface of cancer cells by nanocarriers loaded with cytotoxic drugs is a viable strategy in nanobiotechnology to enhance cancer cell killing and minimize side effects.
View Article and Find Full Text PDFInnate Immun
October 2019
Many studies have demonstrated that (IL-18) polymorphisms (including -137C/G and -607A/C) are correlated with the risk of tuberculosis. However, the meaning of this finding remains a matter of debate. In this study, electronic databases, including PubMed, EMBASE, Web of Science, Google Scholar and CNKI, were systemically queried to identify relevant studies.
View Article and Find Full Text PDFAn aptamer-based fluorometric assay is described for the determination of bisphenol A (BPA). The aptamer against BPA is first attached to the surface of the red AuNPs, and this prevents the AuNPs from salt-induced formation of a blue-colored aggregate. Hence, the blue fluorescence of added nitrogen-doped carbon dots (NCDots) is quenched via an inner filter effect (IFE) caused by the red AuNPs.
View Article and Find Full Text PDFNew molecular signatures are needed to improve the diagnosis of thyroid cancer (TC) and avoid unnecessary surgeries. In this study, we aimed to develop a robust and individualized diagnostic signature in TC. Gene expression profiles of tumor and nontumor samples were from 13 microarray datasets of Gene Expression Omnibus (GEO) database and one RNA-sequencing dataset of The Cancer Genome Atlas (TCGA).
View Article and Find Full Text PDFAphis gossypii, one of the most important agricultural pests in the world, can cause serious economic losses in the main crop-producing areas. To clarify issues such as the genetic differentiation, genetic structure, and demographic history of A. gossypii populations, we used 10 nuclear microsatellite loci (SSR) and two mitochondrial gene sequences (COI and Cytb) to investigate genetic diversity and population structure of A.
View Article and Find Full Text PDFJ Mol Endocrinol
July 2016
Liraglutide, a human glucagon-like peptide (GLP1) analog that partially inhibits dipeptidyl-peptidase 4 (DPP4), can decrease glucose levels and suppress appetite in patients with type 2 diabetes (T2DM). GLP1 and its receptor (GLP1R) also exist in the taste buds of rodents and regulate taste sensitivity. DPP4, a protease, functions in homeostasis of blood glucose, lipids, and body weight.
View Article and Find Full Text PDFACS Appl Mater Interfaces
April 2016
It has been reported that Arabidopsis thaliana leaf trichome can act as a mechanosensory switch, transducing mechanical stimuli into physiological signals, mainly through a buckling instability to focus external force (e.g., exerted by insects) on the base of trichome.
View Article and Find Full Text PDFTrichomes ('hair cells') on Arabidopsis thaliana stem and leaf surfaces provide a range of benefits arising from their shape and disposition. These include tempting herbivores to sample constitutive toxins before they reach the bulk of the tissue. We asked whether, in addition, small mechanical disturbances such as an insect can make elicit signals that might help the plant respond to herbivory.
View Article and Find Full Text PDFEvodiamine (Evo), extracted from the Chinese herbal medicine Evodia rutaecarpa, has cytotoxic effects on different types of human cancer cells. However, its effects on drug resistance and their molecular mechanism and therapeutic target in colorectal cancer are not well understood. In the present study, we observed that Evo inhibited cell growth and induced apoptosis in adose-and time-dependent manner in HCT-116/L-OHP cells.
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