Therapeutic strategies for retention of cranioplasty titanium mesh after mesh exposure.

Background: Titanium mesh exposure after cranioplasty is a possible complication and is usually managed by mesh removal and flap transfer, but the advantages of the rigid prosthesis are then lost. This study aimed to present our experience with negative pressure wound therapy combined with soft tissue dilation for retaining the titanium mesh in patients with mesh exposure after cranioplasty.

Methods: This retrospective study included patients treated between 01/2016 and 05/2019 at the Jiangyin Hospital Affiliated to Southeast University School of Medicine.

Diagnostic Value and Prognostic Evaluation of Autophagy-Related Protein Expression Level in Sepsis Complicated with Acute Respiratory Distress Syndrome.

Objective: To explore the diagnostic value and prognostic evaluation of the autophagy-related protein expression level among patients with sepsis comorbid with acute respiratory distress syndrome.

Methods: A total of 182 sepsis patients were admitted to Naval Medical Center from March 2016 to April 2020 and divided into the acute respiratory distress syndrome and non-ARDS groups. Immunoblotting was employed to identify the expression of autophagy-associated protein from participants' peripheral blood mononuclear cells.

Almost periodic solutions for a SVIR epidemic model with relapse.

This paper is devoted to a nonautonomous SVIR epidemic model with relapse, that is, the recurrence rate is considered in the model. The permanent of the system is proved, and the result on the existence and uniqueness of globally attractive almost periodic solution of this system is obtained by constructing a suitable Lyapunov function. Some analysis for the necessity of considering the recurrence rate in the model is also presented.

Unusual Bicyclo[3.2.1]Octanoid Neolignans from Leaves of and Their Effect on Pyruvate Dehydrogenase Activity.

Three undescribed bicyclo[3.2.1]octanoid neolignan glucosides, along with a known neolignan, were isolated from the leaves of Ruiz & Pav.

Polymorphisms in the DC-SIGN gene and their association with the severity of hand, foot, and mouth disease caused by enterovirus 71.

Severe hand, foot, and mouth disease (HFMD) caused by enterovirus 71 (EV71) infection is associated with high mortality and disability. DC-SIGN, a receptor for EV71, is widely distributed in dendritic cells and may influence the severity of HFMD caused by EV71 infection. This observational study attempts to explore whether single-nucleotide polymorphisms (SNPs) in DC-SIGN are related to the severity of EV71-associated HFMD.

Anti-allergic Inflammatory Components from the Leaves of Piper crocatum Ruiz & Pav.

Piper crocatum Ruiz & Pav. (P. crocatum), a traditional medicinal plant, has been shown to possess various pharmacological activities, including anticancer activity, antioxidant activity, antibacterial activity, anti-hyperglycemic activity, anti-allergic inflammatory activity and others.

[Responses of transpiration to variation in evaporative demands and soil water in a larch plantation at the south side of Liupan Mountains, China].

Quantifying the response of tree transpiration () to the variation of soil water supply capability and atmospheric evaporative demand is beneficial for a better prediction of water use and hydrological cycles in forests and deepen the understanding of the relationship between forest and water. in the Xiangshuihe watershed at the south side of Liupan Mountains was used as the research object. We simultaneously monitored sap flow density by thermal diffusion probe and the environmental factors.

Coumarin and Moracin Derivatives from Mulberry Leaves ( L.) with Soluble Epoxide Hydrolase Inhibitory Activity.

This study identified three coumarins (-), and six moracin derivatives (-). The structures of these natural compounds were determined by the spectroscopic methods, including 1D and 2D NMR methods, and comparison with previous reported data. All of the isolated compounds were assessed for the effects on the soluble epoxide hydrolase (sEH) inhibitory activity.

Anti-Melanogenic Effect of and Its Active Components Protein Kinase A/Cyclic Adenosine Monophosphate-Responsive Binding Protein- and p38 Mitogen-Activated Protein Kinase-Mediated Microphthalmia-Associated Transcription Factor Downregulation.

H. Lév has been reported to have some pharmacologic activities and also interested in functional cosmetics. We found that the water extract of leaves significantly inhibited tyrosinase activity and melanin formation in α-melanocyte stimulating hormone (MSH)-induced B16-F10 cells.

Identification of potential inflammatory inhibitors from Aster tataricus.

Aster tataricus L.f. is a traditional Eastern Asian herbal medicine used for the relief of cough-related illnesses.

Comparative analysis of a panel of biomarkers related to protein phosphatase 2A between laryngeal squamous cell carcinoma tissues and adjacent normal tissues.

Laryngeal squamous cell carcinoma (LSCC) is the most common type of head and neck squamous cell carcinoma (HNSCC) worldwide. Protein phosphatase 2A (PP2A) dysfunction has been widely reported in a broad range of malignancies due to its distinctive role in miscellaneous cellular processes. However, it is poorly understood whether aberrant alterations of PP2A are involved in the network of oncogenic events in LSCC.

Isolation of Two New Compounds and Other Constituents from Leaves of and Study of Their Soluble Epoxide Hydrolase Activities.

Two new phenolic glucosides, pipercroside A and B ( and ), along with 10 known compounds were isolated from the leaves of Ruiz & Pav. Their chemical structures were elucidated through extensive spectroscopic analyses, including 1D and 2D NMR experiments and HR-ESI-MS analysis and comparison with previously reported data. All the isolated compounds were assessed for soluble epoxide hydrolase (sEH) inhibitory activity.

Association of polymorphisms in the vitamin D receptor gene with severity of hand, foot, and mouth disease caused by enterovirus 71.

Severe hand, foot, and mouth disease (HFMD) is sometimes associated with critical complications that can cause substantial child mortality. Activity of the vitamin D receptor (VDR) may influence the outcomes of enterovirus 71 (EV71) infection. This case-control study aimed to assess the association of single-nucleotide polymorphisms (SNPs) in the gene encoding the VDR with the severity of EV71-associated HFMD.

Identification of Anti-Melanogenesis Constituents from L. Leaves.

The individual parts of L. including root bark, branches, leaves, and fruits are used as a cosmetic ingredient in many Asian countries. This study identified several anti-melanogenesis constituents in a 70% ethanol extract of leaves.

[Effects of balanced fertilization on growth and fruit quality of 'Huang-guan' pear on desert area.].

A field experiment was carried out to study the effects of balanced fertilization on growth and development, yield, fruit quality and mineral content in 'Huang-guan' pear to provide a theoretical basis for the reasonable level of fertilization in pear orchards. Four treatments were arranged with 12-year old 'Huang-guan' pear trees from the same orchard: conventional fertilization (CK), low levels of N, PO and high level of S (T), medium levels of N, PO and S (T), high levels of N, PO and low level of S (T). The results showed that different treatments had little effect on the growth and development of current-year branch and leaves in the first year.

[Canopy transpiration of Larix principis-rupprechtii plantation and its impact factors in diffe-rent slope locations at the south side of Liupan Mountains, China.].

Based on a continuous field observation in the Larix principis-rupprechtii plantation plots, located at the upper (P), middle-upper (P), middle (P), middle-lower (P), and lower (P) positions, in a southeast-facing slope of the Xiangshuihe watershed of Liupan Mountains, China, the stem sap flow was observed with the thermal diffusivity probe method. The soil water potential and meteorological factors were monitored from May to October, 2014. We found significant differences among slope positions in the daily forest transpiration (T, mm·d), with an order of P (0.

Anti-allergic inflammatory components from Sanguisorba officinalis L.

Sanguisorba officinalis L. was well known as a traditional herbal medicine to treat inflammation and allergic skin diseases. The aim of this research was to indentify compounds with anti-allergic inflammatory property.

Changes in hydrogen sulfide in rats with hepatic cirrhosis in different stages.

This study aimed to observe changes in the hydrogen sulfide (HS) system in the blood and liver tissue of rats with hepatic cirrhosis at different stages by studying the effect of HS on the course of hyperdynamic circulation in rats with hepatic cirrhosis. HS concentration in the blood from the portal vein and inferior vena cava of hepatic cirrhosis rat model induced with carbon tetrachloride was detected on the 15th, 30th, and 52nd day. The expression of cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE) protein, and CBS and CSE mRNA in the liver was detected by immunohistochemistry and reverse transcriptase polymerase chain reaction (RT-PCR), respectively.

Standardization of extract mixture of Chaenomeles sinensis and Phyllostachys bambusoides for anti-obesity by HPLC-UV.

JM-101 is a developed functional food formula using water extract of Chaenomeles sinensis and Phyllostachys bambusoides for anti-obesity. Standardization and quality control of herb mixture is more difficult than those of single herb. Additionally, the estimation of mixing ratio is an essential requirement for standardization.

Lipolytic effect of compounds isolated from leaves of mulberry (Morus alba L.) in 3T3-L1 adipocytes.

In this study, 19 known compounds were isolated from mulberry (Morus alba L.) leaves. The lipid accumulation inhibitory activity of the isolated compounds was investigated.

Ab initio calculations of torsionally mediated hyperfine splittings in E states of acetaldehyde.

Quantum chemistry packages can be used to predict with reasonable accuracy spin-rotation hyperfine interaction constants for methanol, which contains one methyl-top internal rotor. In this work we use one of these packages to calculate components of the spin-rotation interaction tensor for acetaldehyde. We then use torsion-rotation wavefunctions obtained from a fit to the acetaldehyde torsion-rotation spectrum to calculate the expected magnitude of hyperfine splittings analogous to those observed at relatively high values in the E symmetry states of methanol.