Calixarene incorporated molecular imprinting on covalent organic framework for supramolecular recognition and specific extraction of citrinin.

Specific recognition and selective extraction of mycotoxin in environmental and food matrixes is significant to guarantee public health. Covalent organic frameworks (COFs) are promising adsorbents with tailorable functionality, but their low binding affinity and poor selectivity hamper their wide application for selective extraction of trace mycotoxin from complex matrix. Herein, we report calixarene incorporated molecular imprinting on COF to prepare molecularly imprinted calix[4]arene-containing COF (MICOF-CX4) for supramolecular recognition and specific adsorption of citrinin.

Co coordination-assisted molecularly imprinted covalent organic framework for selective extraction of ochratoxin A.

Covalent organic frameworks (COFs) are attractive materials for sample pretreatment due to their tunable structures and functions. However, the precise recognition of contaminant in complex environmental matrices by COFs remains challenging owing to their insufficient specific active sites. Herein, we report Co coordination-assisted molecularly imprinted flexible COF (MI-COF@Co) for selective recognition of ochratoxin A (OTA).

Integrating molecular imprinting into flexible covalent organic frameworks for selective recognition and efficient extraction of aflatoxins.

Covalent organic frameworks (COFs) are promising adsorbents for extraction, but their selectivity for molecular recognition remains a challenging issue due to the very limited structural design with rigid structure. Herein, we report an elegant strategy for the design and synthesis of molecularly imprinted flexible COFs (MI-FCOFs) via one-pot reaction between the flexible building block of 2,4,6-tris(4-formylphenoxy)- 1,3,5-triazine and linear 4-phenylenediamine for selective extraction of aflatoxins. The flexible chain structure enabled the developed MI-FCOF to adjust the shape and conformation of frameworks to suit the template molecule, giving high selectivity for aflatoxins recognition.

Lead exposure disturbs ATP7B-mediated copper export from brain barrier cells by inhibiting XIAP-regulated COMMD1 protein degradation.

The brain barrier is an important structure for metal ion homeostasis. According to studies, lead (Pb) exposure disrupts the transportation of copper (Cu) through the brain barrier, which may cause impairment of the nervous system; however, the specific mechanism is unknown. The previous studies suggested the X-linked inhibitor of apoptosis (XIAP) is a sensor for cellular Cu level which mediate the degradation of the MURR1 domain-containing 1 (COMMD1) protein.

The dissection of R genes and locus Pc5.1 in Phytophthora capsici infection provides a novel view of disease resistance in peppers.

Background: Phytophthora capsici root rot (PRR) is a disastrous disease in peppers (Capsicum spp.) caused by soilborne oomycete with typical symptoms of necrosis and constriction at the basal stem and consequent plant wilting. Most studies on the QTL mapping of P.

[Effects of beta glucan in highland barley on blood glucose and serum lipid in high fat-induced C57 mouse].

Objective: Study the effects of β-glucan in highland barley on blood glucose and serum lipid in high fat diet induced C57 mouse.

Methods: Using table of random number, 40 male C57BL/6 mice were randomly divided into 4 groups (10 mice in each group) by weight: high dosage group (4% β-glucan and high fat diet), low dosage group (2% β-glucan and high fat diet), high fat diet group and normal control group. Food-intake and body weight of C57 mouse were observed.

Non-isothermal thermal decomposition reaction kinetics of 2-nitroimino-5-nitro-hexahydro-1,3,5-triazine (NNHT).

The thermal behavior and decomposition reaction kinetics of 2-nitroimino-5-nitro-hexahydro-1,3,5-triazine (NNHT) were investigated by TG-DTG and DSC under atmospheric pressure and flowing nitrogen gas conditions. The results show that the thermal decomposition process of NNHT has two mass loss stages. The exothermic decomposition reaction mechanism obeys chemical reaction rule.

[Simultaneous determination of trace amounts of iron(II), copper(I) and cobalt(II) in aloe by second derivative peak area spectrophotometry].

A new method for simultaneous determination of iron(II), copper(I) and cobalt(II) was established by second derivative peak area spectrophotometry in chromogenic system of 1,10-phenanthroline. The method could avoid disturbing by some ions. The accuracy and sensitivity were improved.