Two new species of the sac-spider genus Clubiona Latreille, 1804 (Araneae, Clubionidae) and the female of C. subcylindrata from China.

Two new species of the genus Clubiona Latreille, 1804 are described: C. tianpingshan sp. nov.

Clinical Impacts and Outcomes With Possible Donor-Derived Infection in Infected Donor Liver Transplantation: A Single-Center Retrospective Study in China.

Background: Information on possible donor-derived transmission events in China is limited. We evaluated the impacts of liver transplantation from infected deceased-donors, analyzed possible donor-derived bacterial or fungal infection events in recipients, and evaluated the etiologic agents' characteristics and cases outcomes.

Methods: A single-center observational study was performed from January 2015 to March 2017 to retrospectively collect data from deceased-donors diagnosed with infection.

[Establishment of a model of endoplasmic reticulum stress response in dental pulp cells induced by tunicamycin].

Purpose: The aim of this study was to establish a model of endoplasmic reticulum (ER) stress in dental pulp cells(DPCs) induced by tunicamycin to better understand the molecular mechanism of DPCs related diseases mediated by ER stress.

Methods: DPCs were cultured using modified tissue explant technique in vitro and cultured in presence or absence of tunicamycin. DPCs' viability was measured by methylthiazol tetrazolium (MTT) assay.

Steamed root of Rehmannia glutinosa Libosch (Plantaginaceae) alleviates methotrexate-induced intestinal mucositis in rats.

Ethnopharmacological Relevance: Intestinal mucositis induced by chemotherapy is a severe clinical problem in cancer patients that currently lack effective interventions. In traditional Chinese medicine, chemotherapeutic toxicity is diagnosed as Qi and Yin deficiency, and steamed rehmannia root (SRR) is frequently prescribed to these patients. Whether SRR can prevent the adverse effects remains to be confirmed experimentally.

Effects of deferoxamine on the repair ability of dental pulp cells in vitro.

Introduction: In previous studies, we found that hypoxia promoted the mineralization of dental pulp cells (DPCs). However, the clinical application of hypoxia as a therapy is questionable or unfeasible. Deferoxamine (DFO), a medication for iron overload, has also been shown to induce hypoxia.

[The influence of zi-hua burn cream on the survival of random skin flaps in rats].

Objective: To observe the effect of zi-hua burn cream on the survival of skin flaps in rats, and its mechanisms.

Methods: 72 Wistar rats, were randomly divided into four groups as zi-hua group(n = 18, external application of alfalfa burn cream), control group (n = 18, external application of heparin sodium cream), model group (n = 18, external application of vaseline) , negative control (n = 18, no operation). 8 cm x 2 cm random skin flaps with pedicle on the side of head were designed on the back of Wistar rats.

Hydrogen peroxide induces apoptosis in human dental pulp cells via caspase-9 dependent pathway.

Introduction: Reactive oxygen species are a group of metabolic intermediates produced during oxidative metabolism in eukaryotic cells. They include superoxide anion (O2(-)), hydrogen peroxide (H2O2), hydroxyl radical (·OH), and (1)O2. Of these intermediates, H2O2 is the most stable.

A novel COL7A1 gene mutation causing pretibial epidermolysis bullosa: report of a Chinese family with intra-familial phenotypical diversity.

Pretibial epidermolysis bullosa (PEB) is an extremely rare subtype of dominant dystrophic epidermolysis bullosa (DDEB) caused by mutation of the COL7A1 gene. More than 730 mutations have been identified in patients with DDEB, but only five mutations have been found to be related to PEB. In this study, a novel heterozygous nucleotide G>T transition at position 6101 in exon 73 of COL7A1 was detected, which resulted in a glycine to valine substitution (G2034V) in the triple-helical domain of type-VII collagen.

Isolation and identification of CXCR4-positive cells from human dental pulp cells.

Introduction: In previous studies, we found expression of stromal cell-derived factor-1α (SDF-1α)/CXC chemokine receptor 4 (CXCR4) in human dental pulp and the SDF-1α-CXCR4 axis might play a role in the recruitment of CXCR4-positive dental pulp cells (CXCR4(+) DPCs) toward the damaged sites. However, the specific function of CXCR4(+) DPCs in the injured dental pulp was still unknown. The purpose of this study was to isolate CXCR4(+) DPCs from dental pulp cells in vitro to pave the way for further study of their characteristics.

Proliferation and multilineage potential of CXCR4-positive human dental pulp cells in vitro.

Introduction: Although the results of our previous studies showed that the stromal cell-derived factor (SDF)-1α-CXC chemokine receptor 4 (CXCR4) axis may play a role in the recruitment of CXCR4-positive dental pulp cells (CXCR4(+) DPCs) toward the damaged sites, the specific function of CXCR4(+) DPCs in the injured dental pulp was still unknown. The purpose of this study was to verify whether CXCR4(+) DPCs possessed stem cells properties so that we can understand their role in area of injury.

Methods: CXCR4(+) DPCs were isolated from normal DPCs with magnetic-activated cell sorting.

[A clinical analysis of fetal chromosomal aberration induced by paint and hair dye].

Objective: To analyze the effect of long-term exposure to paint or hair dye on chromosomal aberration of early embryos.

Methods: We analyzed 2 cases of fetal or infantile chromosome aberration in which the parents experienced long-term exposure to paint and hair dye.

Result: The chromosomal mutations were detected in one 3-month-old infant and one 21-week-old fetus, and the karyotypes were 46,XX,del(2)(pter'q31) and 46,XX, t(4;12;15), respectively.

[Analysis of Down syndrome screening by maternal serum detection in mid-pregnancy].

Objective: To study the clinical value of screening chromosomal diseases and abnormal pregnancy by maternal serum examination in mid-pregnancy.

Methods: Maternal serum AFP and F-beta hCG were detected in the mid-pregnancy (16-20 weeks) using commercially available detection kits, and the risk of Down syndrome was calculated taking into account of such factors as the maternal age, gestational age, and body weight. Those at high risk underwent amino fluid or cordocentesis for fetal karyotpying.

[Changes of peripheral blood chromosomal centromere aberration in patients with cytomegalovirus infection after anti-viral treatment].

Objective: To study the changes of peripheral blood chromosomal centromere aberration in patents with cytomegalovirus (CMV) infection after anti-viral treatment.

Methods: Sixty-two patients with early spontaneous abortion and CMV infection analyzed for their peripheral blood chromosomal centromere using simultaneous silver staining before and after anti-viral treatment.

Results: The patients with CMV infection had high rate of centromere aberration, which was decreased significantly after anti-viral treatment (P<0.

[The study of the mechanism of the effect of heparin on tissue perfusion of sepsis patients].

Objective: To assess the role of heparin administration in the early stage of sepsis and its mechanism of action.

Methods: This was a prospective study. One hundred and nineteen patients were enrolled in the study and were randomly divided into control group (64 cases) and therapy group (55 cases).

[Effect of low molecular heparin sodium cream on the content of serum nitric oxide in random pattern skin flap: experiment with rats].

Objective: To explore the mechanism of improvement of blood circulation in random pattern skin flap by low molecular heparin sodium cream.

Methods: 48 Wistar rats underwent formation of random skin flap of the size of 2 cm x 8 cm on the back and then were randomly divided into 2 equal groups: experiment group with low molecular heparin sodium cream smeared on the skin flaps and control group with Vaseline smeared on the skin flaps. 24, 48, and 72 hours, and 7 days after the smearing blood samples were collected from 6 rats respectively to detect the content of serum nitric oxide a (NO).

[The drug resistance of pathogenic bacteria of nosocomial infections in surgical intensive care unit].

Objective: To investigate the drug resistance of pathogenic bacteria of nosocomial infections in the surgical intensive care unit.

Methods: The drug resistance of pathogenic bacteria of nosocomial infections in the SICU in our hospital from January 2001 to December 2004 were analyzed.

Results: The average nosocomial infections rate was 11.