Transcriptome analysis of reveals molecular signature of saccharide impact on acarbose biosynthesis.

Different carbon sources lead to differential acarbose production in . To uncover the underlying differentiation in the context of genes and pathways, we performed transcriptome sequencing of ZJB-03852 grown on different saccharides, such as glucose, maltose, or the saccharide complex consisting of glucose plus maltose. The differentially expressed genes were classified into GO (gene ontology) terms and KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways for functional annotations.