CDK12 Promotes the Proliferation, Migration, and Angiogenesis of Gastric Carcinoma via Activating the PI3K/AKT/mTOR Signaling Pathway.

Cyclin-dependent kinase 12 (CDK12) has been found to regulate tumor progression. However, its function in gastric carcinoma (GC) remains controversial. This work aimed to explore the exact effect of CDK12 on GC progression.

Enhancing the efficiency of planar heterojunction perovskite solar cells via interfacial engineering with 3-aminopropyl trimethoxy silane hydrolysate.

The interfacial compatibility between compact TiO and perovskite layers is critical for the performance of planar heterojunction perovskite solar cells (PSCs). A compact TiO film employed as an electron-transport layer (ETL) was modified using 3-aminopropyl trimethoxy silane (APMS) hydrolysate. The power conversion efficiency (PCE) of PSCs composed of an APMS-hydrolysate-modified TiO layer increased from 13.

Hyperthermic intraperitoneal chemotherapy plus high-frequency diathermic therapy followed by intravenous chemotherapy versus intravenous chemotherapy alone for postoperative adjuvant treatment of gastrointestinal cancer: a comparative research study.

Purpose: To evaluate the therapeutic efficacy and toxicity of hyperthermic intraperitoneal chemotherapy (HIPEC) plus high-frequency diathermic therapy (HFDT) followed by intravenous chemotherapy vs intravenous chemotherapy alone for adjuvant treatment of postoperative gastrointestinal neoplasms.

Methods: Fifty-two gastrointestinal carcinoma patients who were radically operated were enrolled and divided into the treatment group and the control group. In the treatment group, 25 patients were treated with combination of HIPEC+HFDT and subsequent intravenous chemotherapy, while in the control group 27 patients received intravenous chemotherapy alone.

Targeting miR-155 suppresses proliferation and induces apoptosis of HL-60 cells by targeting Slug/PUMA signal.

Recent studies have shown that high miR-155 expression was associated with poor prognosis in patients with acute myelogeneous leukemia (AML). Furthermore, targeting miR-155 results in monocytic differentiation and apoptosis. However, the exact role and mechanisms of miR-155 in human AML remains speculative.

[The New Bacteria Expressing Recombinant Multi-epitope Vaccine against Helicobacter pylori and Its Microbiological Characteristics].

Ojective: To construct the engineering bacteria with recombinant plasmid expressing the multi-epitope vaccine which composed of Helicobacter pylori urea membrane channel protein (UreI), Helicobacter pylori urease B subunit (UreB) and cholera toxin B subunit (CTB), and then to study it's microbiological characteristics.

Methods: The sequence contains some dominant epitopes of Helicobacter pylori UreI and UreB was designed, and ctB was added at the N-terminal, all the sequence were linked by flexible linkers. Codon optimization was done according to Escherichia coli (E.

[Ex-situ remediation of PAHs contaminated site by successive methyl-beta-cyclodextrin enhanced soil washing].

Polycyclic aromatic hydrocarbon (PAH) polluted sites caused by abandoned coking plants have attracted great attentions. This study investigated the feasibility of using methyl-beta-cyclodextrin (MCD) solution to enhance ex situ soil washing for extracting PAHs. Treatment with elevated temperature (50 degrees C) in combination with ultrasonication (35 kHz, 30 min) at 100 g x L(-1) was effective.

[Optimizing remediation conditions of non-thermal plasma for DDTs heavily contaminated soil].

A series of experiments were carried out in a non-thermal reactor to remove DDTs in heavily contaminated soil by dielectric barrier discharge (DBD). The study aims to investigate the effects of soil properties (including soil particle size and soil water content) and equipment working parameters (e. g.

[In-situ remediation of polychlorinated biphenyls polluted soil by ecological controlling measures: a field trial].

A field experiment was conducted to study the remediation of agricultural soils polluted with polychlorinated biphenyls (PCBs) by several ecological controlling measures. After sequential stages of liming, plowing, planting alfalfa and paddy, a significant part of PCBs was removed from the soil, with an average removal rate of 86.9%.

[Phytoremediation of polychlorinated biphenyls contaminated soil by leguminosae-gramineae intercropping: a field trial].

Phytoremediation of polychlorinated biphenyls (PCBs) contaminated soil by leguminosae (alfalfa) and gramineae (ryegrass and tall fescue) was studied in a field trial. All planted treatments had significantly higher PCBs removal efficiency compared with those of unplanted control after 270 days of in-situ phytoremediation. Alfalfa monoculture received the highest removal efficiency of soil PCBs by 59.

[Sorption behavior of PCB28 to phosphatidylcholine and triglyceride].

Sorption behaviors of PCB28 to phosphatidylcholine (PC)and triglyceride (TG) were studied. Results showed that sorption equilibrium could be achieved in 8 h for PCB28, and the sorption amount on PC was higher than that of TG when the initial PCB28 concentration is in the range of 50-250 microg x L(-1). As the initial PCB28 concentration increases, the absolute sorption amount and relative sorption amount on PC and TG enhances.

Phytoremediation of oilfield sludge after prepared bed bioremediation treatment.

A field-scale experiment was carried out to compare the effectiveness of five plant species in the remediation of oily sludge. Alfalfa, tall fescue, and soybean substantially increased the removal rate of oil and grease (O&G) after 120 days of remediation. Of these, soybean treatment showed the highest removal rate of 34.

[Effects of Rhizobium meliloti on PCBs degradation and transformation in solution culture].

The capability of Rhizobium meliloti on degrading 2,4,4'-trichlorobiphenyl and 18 kinds of polychlorinated biphenyl congener mixtures was studied by shaking flask experiment. The results showed that the degradation capability of Rhizobium meliloti to 2, 4, 4'-trichlorobiphenyl increased gradually with the increasing concentration of 2, 4, 4'-trichlorobiphenyl. After 7 days, the degradation rates of 2, 4, 4'-trichlorobiphenyl under 1.

Enhanced removal of polychlorinated biphenyls from alfalfa rhizosphere soil in a field study: the impact of a rhizobial inoculum.

Polychlorinated biphenyls (PCB) are persistent pollutants in soil environments where they continue to present considerable human health risks. Successful strategies to remediate contaminated soils are needed that are effective and of low cost. Bioremediation approaches that include the use of plants and microbial communities to promote degradation of PCB have significant potential but need further assessment under field conditions.

[Spatial distribution of soil PCBs congeners in typical area of Yangtze River Delta region].

191 surface farmland soil samples were collected from an area of 27 km2 in typical polluted county of the Yangtze River Delta region and analyzed for concentrations of 16 kinds of polychlorinated biphenyls. The results of statistical analysis indicated that the concentrations of PCBs in the soils ranged from 0.01-484.

[Combined remediation effects of arbuscular mycorrhizal fungi-legumes-rhizobium symbiosis on PCBs contaminated soils].

The combined remediation effects of dual inoculation with an arbuscular mycorrhizal fungus (AM) and rhizabium (Rhizobium meliloti) with a host plant (alfalfa) on PCBs contaminated soils was studied using pot experiments. The results showed that alfalfa had a clear role in PCBs removal in soils compared with treatments without alfalfa and inoculated microorganisms, PCBs concentration in lightly and heavily polluted soils decreased 15.8% and 23.

[Improvement of left ventricular hypertrophy by anemic-correcting erythropoietin therapy in chronic renal insufficiency].

Objective: Left ventricular hypertrophy (LVH) is an independent predictor of morbidity and mortality in dialysis patients. It remains unclear whether efforts to correct anemia in patients with mild-to-moderate chronic renal insufficiency (CRI) can reverse LVH. This prospective multi-center Chinese cohort study evaluates left ventricular mass index (LVMI) evolution in anemic CRI patients with or without recombinant human erythropoietin (rHuEPO) therapy.