Efficient dual-phase PtNiCuMnMo high-entropy alloy electrocatalyst for alkaline hydrogen evolution reaction.

The realisation of high-performance cathodic hydrogen evolution reaction (HER) is of considerable importance for the development of the nascent hydrogen economy. Herein, we develop a dual-phase PtNiCuMnMo high-entropy alloy (HEA) showing excellent alkaline HER performance with an overpotential of as low as 44 mV at a current density of 10 mA/cm. Additionally, the PtNiCuMnMo HEA catalyst maintains stability after 72 h at a current density of 200 mA/cm.

Assessment of early factors for identification or prediction severe acute pancreatitis in pregnancy.

Background: Acute pancreatitis in pregnancy (APIP) is a rare and serious condition, and severe APIP (SAPIP) can lead to pancreatic necrosis, abscess, multiple organ dysfunction, and other adverse maternal and infant outcomes. Therefore, early identification or prediction of SAPIP is important.

Aim: To assess factors for early identification or prediction of SAPIP.

Transcription factor triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.

Bacterial or viral infections, such as , mumps virus, herpes simplex virus, and Zika virus, destroy immune homeostasis of the testes, leading to spermatogenesis disorder and infertility. Of note, recent research shows that SARS-CoV-2 can infect male gonads and destroy Sertoli and Leydig cells, leading to male reproductive dysfunction. Due to the many side effects associated with antibiotic therapy, finding alternative treatments for inflammatory injury remains critical.

inhibits differentiation of porcine-induced pluripotent stem cells through MAPK and PI3K signaling regulation.

As a transcription factor of the Pit-Oct-Unc (POU) domain family, octamer-binding transcription factor 6 ( ) participates in various aspects of stem cell development and differentiation. At present, however, its role in porcine-induced pluripotent stem cells (piPSCs) remains unclear. Here, we explored the function of in piPSCs.

CT-guided transthoracic pulmonary artery catheterization: an experimental study in a porcine model.

Objectives: We investigated the safety and feasibility of CT-guided transthoracic pulmonary artery catheterization (TPAC) in a porcine model.

Methods: Procedures were conducted on ten mature Bama miniature pigs. After anesthesia, chest CT was performed in the left lateral decubitus position to determine the puncture route.

Four-lncRNA immune prognostic signature for triple-negative breast cancer Running title: Immune lncRNAs predict prognosis of TNBC.

Objective: We aimed to explore key immune-related long non-coding RNAs (lncRNAs) and their effect in predicting of prognosis of triple-negative breast cancer (TNBC).

Methods: Four datasets of TNBC were downloaded from TCGA and GEO databases. ImmPort database was utilized to acquire immune-related mRNAs.

[High-Frequency Dynamics of Water Quality and Phytoplankton Community in Inflowing River Mouth of Xin'anjiang Reservoir, China].

The tail of the reservoir is the unstable zone regarding water quality and phytoplankton community. Therefore, it is the crucial zone in aquatic ecosystem transitions. To understand the transition characteristics and driving mechanisms of water environment dynamics, high-frequency monitoring of the water environment and phytoplankton community in the tail of a deep and large reservoir, the Xin'anjiang Reservoir in southeast of China, was conducted using a water quality monitoring buoy and three-day interval water sampling during 18 months.

[Long-term Variation Characteristics of Zooplankton Community Structure in Meiliang Bay, Lake Taihu].

Zooplankton, as an important part of the water food chain, plays an important role in lake ecosystems. It is an important monitoring indicator for water bodies. However, due to the lack of long-term monitoring data of zooplankton community structure, there is a lack of understanding about its long-term characteristics.

Effect of Regulatory Network of Exosomes and microRNAs on Neurodegenerative Diseases.

Objective: A comprehensive review of the network regulation of exosomes and microRNAs (miRNAs) in neurodegenerative diseases was done, centering on the mechanism of the formation of exosomes and miRNAs and the sorting mechanism of exosomal miRNAs, with the aim to provide a theoretical basis in the search of biomarkers and the treatment of neurodegenerative diseases.

Data Sources: The comprehensive search used online literature databases including NCBI PubMed, Web of Science, Google Scholar, and Baidu Scholar.

Study Selection: The study selection was based on the following keywords: exosomes, miRNAs, central nervous system (CNS), and neurodegenerative diseases.

In vitro DNA SCRaMbLE.

The power of synthetic biology has enabled the expression of heterologous pathways in cells, as well as genome-scale synthesis projects. The complexity of biological networks makes rational de novo design a grand challenge. Introducing features that confer genetic flexibility is a powerful strategy for downstream engineering.

[Study of Kinase Inhibitor WP1066 on the STAT3/JAK2 of Prostate Stromal Cells].

Objective: To study the role of JAK2 signaling pathway in prostate stromal cells and the effect of inhibitor WP1066 on its expression.

Methods: The phosphorylation of JAK2 and STAT3 in prostate tissues of patients with benign prostatic hyperplasia (BHP) (=4) and severe histological prostatitis (HP) plus BPH (=4) was tested by using Western blot to verify the activation of their mediated signaling pathway. Kinase inhibitor WP1066 was added to prostate stromal cells to detect inhibition of the JAK2 and STAT3 activation launched by IL-6.

Pollen competition between morphs in a pollen-color dimorphic herb and the loss of phenotypic polymorphism within populations.

Flower color polymorphism is relatively uncommon in natural flowering plants, suggesting that maintenance of different color morphs within populations is difficult. To address the selective mechanisms shaping pollen-color dimorphism, pollinator preferences and reproductive performance were studied over three years in Epimedium pubescens in which some populations had plants with either green or yellow pollen (and anthers). Visitation rate and pollen removal and receipt by the bee pollinator (Andrena emeishanica) did not differ between the two color morphs.

Development of 15 polymorphic microsatellite markers for (Moraceae).

Premise Of The Study: (Moraceae) is distributed widely in South and Southeast Asia, Melanesia, and northern Australia, and it is also cultivated outside its original northern range limit in southwestern China. Therefore, the species is well suited to explore the mechanism of range limits of species. However, little is known about its genetic background.

Comparison of efficacy and safety of conventional laparoscopic radical prostatectomy by the transperitoneal versus extraperitoneal procedure.

Worldwide, prostate cancer (PCa) is the second most common malignancy in males. We undertook a meta-analysis to compare the efficacy and safety of conventional laparoscopic radical prostatectomy with a transperitoneal (TLRP) approach, versus that of an extraperitoneal (ELRP) approach, for treatment of localized PCa. A comprehensive literature search retrieved 14 publications, with a total of 1715 patients.

Perioperative restricted fluid therapy preserves immunological function in patients with colorectal cancer.

Aim: To investigate the effect of perioperative restricted fluid therapy on circulating CD4(+)/CD8(+) T lymphocyte ratio, percentage of regulatory T cells (Treg) and postoperative complications in patients with colorectal cancer.

Methods: A total of 185 patients met the inclusion criteria and were included in the randomized clinical trial. These patients were divided into two groups according to receipt of either perioperative standard (S, n = 89) or restricted (R, n = 96) fluid therapy.

[Histological effects of unilateral spermatic cord torsion without removal of the ipsilateral necrotic testis on the contralateral testis in rats].

Objective: To investigate the protective effect of retarded removal of the unilateral necrotic testis after long-time (> 24 h) spermatic cord torsion on the contralateral testis in rats.

Methods: Thirty-three male SD rats aged 21 -42 days were divided into a sham-operation group (n = 11), a torsion-reservation group (n = 12) and a torsion-orchiectomy group (n = 10). The rats of the sham-operation group received dartos pouch orchidopexy on the left testis, while those of the latter two groups underwent 720 degrees unilateral spermatic cord torsion on the left side.

Biodegradation of butachlor by Rhodococcus sp. strain B1 and purification of its hydrolase (ChlH) responsible for N-dealkylation of chloroacetamide herbicides.

Rhodococcus sp. strain B1 could degrade 100 mg/L butachlor within 5 days. Butachlor was first hydrolyzed by strain B1 through N-dealkylation, which resulted in the production of butoxymethanol and 2-chloro-N-(2,6-dimethylphenyl)acetamide.

[Total flavonoids and icariin contents of Epimedium pubescens in different types of communities and their relationships with soil factors].

Epimedium pubescens and soil samples were collected from the Betula albosinensis community (community I ), Cyclobalanopsis glauca var. gracilis community (community II), and Cinnamomum longepaniculatum community (community III) in Tangjiahe Nature Reserve in August 2009, with the total flavonoids and icariin contents in E. pubescens samples measured by high performance liquid chromatography and UV-spectrophotometer, and the relationships between these contents and soil parameters analyzed.

[The contents changes of polysaccharides and total flavonoids during flower bud differentiation of Epimedium sagittatum].

Objective: To study the dynamic changes of the contents of polysaccharides and total flavonoids Daring flower bud differentiation of Epimedium sagittatum.

Methods: The polysaccharides and total flavonoids from Epimedium sagittatum were extracted by Microwave-assisted method. The content of polysaccharides was determined by anthrone sulphuric acid colorimetry and that of total flavonoids was determined at 270 nm by ultraviolet spectrophotometry.

[Studies on purification of total saponins from the leaves of Acanthopanax trifoliatus by macroporous adsorption resin].

Objective: To study the enrichment and purification of total saponins from the leaves of A. trifoliatus.

Methods: Using the total saponins from the leaves of A.

[Study on propagation technology of Acanthopanax trifoliatus by cuttings].

Objective: In order to obtain substantial clonal plants, we studied the cuttings propagation technology.

Methods: The cutting roots and stems of Acanthopanax trifoliatus were used as plant materials, and different materias, seasons and other conditions for cutting propagation were tested.

Results: It showed that the survival rate of stem segments was higher than that of root segments.

Cloning and characterization of a curcin gene encoding a ribosome inactivating protein from Jatropha curcas.

A curcin gene was isolated by using genomic walker technology and revealed to encode the type-1 ribosome inactivating proteins (RIPs). Analysis of 1802 bp segments revealed the gene including a 694 bp 5' flanking region, a 882 bp open read frame (ORF) and a 226 bp 3' flanking region. There are one putative TATA boxes and two possible CAAT box lie in the 5'-flanking region.