Causal association of serum vitamin D levels with urolithiasis: a bidirectional two-sample Mendelian randomization study.

Background: In light of inconsistent evidence from previous observational studies regarding the correlation between serum vitamin D levels and urolithiasis, this study aimed to investigate the genome-wide causal association between genetically predicted serum 25(OH)D levels and urolithiasis using the Mendelian randomization (MR) approach.

Methods: In this study, we utilized genome-wide association studies (GWAS) summary statistics from the UK Biobank and SUNLIGHT consortium for serum vitamin D levels, as well as urolithiasis data from FinnGen. We employed bidirectional two-sample MR analysis to evaluate potential causal relationships.

Development of a fast-responsive and turn on fluorescent probe with large Stokes shift for specific detection of cysteine in vivo.

Cysteine has a great effect on the physiological and pathological processes, which could bring out various diseases such as skin lesions, edema, hair depigmentation, Alzheimer's, Parkinson's, and liver damage due to the abnormal concentrations of cysteine. Therefore, it is of great impoatance to develop a method for imaging Cys. Herein, a novel fluorescent probe was developed for imaging Cys in vivo specially.

The use of a portable ultrasound system in the surgical assessment of rib fractures in an elderly patient.

Introduction: Portable ultrasound is a modality of medical ultrasonography that utilizes small and light devices, and is an established diagnostic method used in clinical settings such as Cardiology, Vascular Surgery, Radiology, Endocrinology, Pediatric and Obstetric & Gynecology.

Presentation Of Cases: We present a case report of 86-years old patient who underwent surgical rib fixation for multiple rib fractures followed by falling from standing height and our management experience.

Discussion: The use of portable ultrasound device in operation theatre demonstrates several advantages.

[Observation on the therapeutic effect of warming needle moxibustion on prolapse of lumbar intervertebral disc].

Objective: To observe the therapeutic effect of warming needle moxibustion on prolapse of lumbar intervertebral disc.

Methods: Seventy-eight cases were randomly divided into a test group and a control group, 39 cases in each group. The control group were treated with acupuncture at Shenshu (BIL 23), Mingmen (GV 4), Yaoyangguan (GV 3) and Weizhong (BL, 40), etc.