Three new Mn-[Mo(CN)] molecular magnets constructed from chiral bidentate chelating ligands.

Three new cyanide-bridged compounds {[Mn((,)-Dpen)][Mn((,)-Dpen)(HO)][Mo(CN)]·4HO·4CHN} (1-SS), {[Mn((,)-Dpen)][Mn((,)-Dpen)(HO)][Mo(CN)]·4.5HO·4CHN} (1-RR), and {[Mn(Chxn)][Mn(Chxn)(HO)][Mo(CN)]·HO·4CHN} (2) (/-Dpen = (,)/(,)-1,2-diphenylethylenediamine and Chxn = 1,2-cyclohexanediamine) have been successfully synthesized from the self-assembly reaction of the [Mo(CN)] unit, the Mn ions, and two chiral bidentate chelating ligands. Single-crystal structure determinations show that compounds 1-SS and 1-RR containing ligands /-Dpen are enantiomers and crystallize in the chiral space group 2.

Testing stem cell therapy in a rat model of inflammatory bowel disease: role of bone marrow stem cells and stem cell factor in mucosal regeneration.

Background: The gastrointestinal (GI) mucosal cells turnover regularly under physiological conditions, which may be stimulated in various pathological situations including inflammation. Local epithelial stem cells appear to play a major role in such mucosal renewal or pathological regeneration. Less is clear about the involvement of multipotent stem cells from blood in GI repair.