Continuous In-Situ Polymerization of Complex-Based Films for High-Performance Electrochromic Devices.

Synthesis of uniform and stable electrochromic films on a conductive layer is one of the effective ways to construct high-performance electrochromic devices. The development of more convenient and feasible polymer film preparation technology is important and necessary. Herein, we demonstrated the development of a continuous in situ polymerization method to prepare electrochromic film on ITO glass through Schiff base condensation of a tetraamine Fe-based complex and organic di-/tri-aldehyde precursors.

Bibliometric analysis of global research on dialectical behavior therapy from 1987 to 2024.

Objective: This study explores researches of dialectical behavior therapy (DBT) in mental health to provide an overview of current knowledge landscape and predict future development trends of DBT.

Method: The bibliometric approach was used in the study. Articles on DBT-related research were retrieved from the Web of Science Core Collection (WoSCC) database up to December 31, 2024, and analyzed using VOSviewer and CiteSpace.

Doping Copper(I) in Ag Cluster for Circularly Polarized OLEDs with External Quantum Efficiency of 26.7 .

Hetero-metal doping or substitution to create alloy clusters is a highly appealing strategy for improving physicochemical characteristics as well as tailoring optical and electronic properties, although high-yield synthesis of alloy clusters with precise positioning of doped metals is a daunting challenge. Herein, we manifest rational synthesis of chiral alloy cluster enantiomers R/S-AgCu in 85 %-87 % yield by replacing one Ag(I) atom with Cu(I) in homometallic clusters R/S-Ag, achieving circularly polarized luminescence (CPL) with a quantum yield beyond 90 %. As a small energy gap (ca.

Synergistic coordination of diphosphine with primary and tertiary phosphorus centers: Ultrastable icosidodecahedral Ag nanoclusters with metallic aromaticity.

As versatile ligands with extraordinary coordination capabilities, RPH (R = alkyl or aryl) are rarely used in constructing metal nanoclusters due to their volatility, toxicity, spontaneous flammability, and susceptibility to oxidation. In this work, we designed a primary and tertiary phosphorus-bound diphosphine chelator (2-PhPCHPH) to create ultrastable silver nanoclusters with metallic aromaticity. By controlling the deprotonation rate of 2-PhPCHPH and adjusting the templates, we successfully synthesized two near-infrared emissive nanoclusters, and , which have analogous icosidodecahedral Ag shells with an symmetry.

Naphthalimide-Modified Clusters for Red-Emitting Devices with High Color Purity.

Conventional fluorescent materials frequently exhibit narrow-band emissions with a small full width at half-maximum (fwhm) due to localized-state characteristics, but electroluminescence is less efficient owing to the utilization of only singlet excitons. In this work, taking advantage of naphthalimide (NAI)-acetylide derivatives with a rigid planar structure and localized transition characteristics, we elaborately designed two mononuclear Pt(II) complexes with weak double emissions of fluorescence and phosphorescence. Taking them as synthetic precursors, we prepared three PtAu heteronuclear clusters and successfully attained highly efficient narrow-band red phosphorescence with the fwhm below 30 nm.

Screening and staging of chronic obstructive pulmonary disease with deep learning based on chest X-ray images and clinical parameters.

Background: Chronic obstructive pulmonary disease (COPD) is underdiagnosed with the current gold standard measure pulmonary function test (PFT). A more sensitive and simple option for early detection and severity evaluation of COPD could benefit practitioners and patients.

Methods: In this multicenter retrospective study, frontal chest X-ray (CXR) images and related clinical information of 1055 participants were collected and processed.

[Human Umbilical Cord-Derived Mesenchymal Stem Cells Prevent Acute Graft-Versus-Host Disease after Hematopoietic Stem Cell Transplantation Via Exosome-Mediated MicroRNA and Its Mechanism].

Objective: To explore molecular mechanisms by which umbilical cord-derived mesenchymal stem cells suppress the development of GVHD after bone marrow hematopoietic stem cell transplantation.

Methods: A mouse model of aGVHD was constructed after bone marrow hematopoietic stem cell transplantation, and the umbilical cord-derived mesenchymal stem cells were cultured, and then injected into the aGVHD mouse model, so as to investigate its prophylactic efficacy. Prophylactic effect of the exosomes isolated from umbilical cord-derived mesenchymal stem cells on aGVHD mice was assessed.

Erratum: suppresses tumor growth and metastasis in nasopharyngeal carcinoma by repressing PI3K/AKT signaling pathway via interaction with Integrin β1 and Merlin: Erratum.

[This corrects the article DOI: 10.7150/ijbs.34785.

Decahexanuclear Zinc(II) Coordination Container Featuring a Flexible Tetracarboxylate Ligand: A Self-Assembly Supermolecule for Highly Efficient Drug Delivery of Anti-Inflammatory Agents.

The application of a coordination container in biomedicine is hindered by single binding domains and unsatisfactory biostability and biocompatibility. Herein, we designed a sulfonylcalix[4]arene-based decahexanuclear zinc(II) coordination container employing a flexible tetracarboxylate ligand as a linker and utilized it as a novel drug delivery system. The coordination container consisting of one endo and four exo cavities provides multiple binding domains for efficient encapsulation of drug molecules as clearly revealed by systematic host-guest studies using NMR techniques of H NMR titration experiments and 2D NOESY and diffusion-ordered NMR spectroscopy studies.

Elaborate Design of d-d Heteronuclear Phosphors for Ultrahigh-Efficiency Solution-Processed Organic Light-Emitting Diodes.

Highly soluble d-d heteronuclear phosphors afford an alternative approach to achieve high-efficiency organic light-emitting diodes (OLEDs) through a solution process. In this work, four highly phosphorescent d-d heteronuclear complexes with significant Pt-Au interactions were prepared. By judicious selection of sterically hindered and π-conjugated substituents in triphosphine ligands, the phosphorescence is dramatically promoted through effectively prohibiting nonradiative thermal relaxation with an efficiency of 0.

Vapor-triggered Green-to-Yellow Luminescence Conversion due to the Variation of Ligand Orientations in Tetranuclear Copper(I) Complex.

The reaction of 3,6-di-butyl-1,8-bis(diphenylphosphino)-9-methyl-9H-carbazole (L) with CuBr resulted in the isolation of tetranuclear copper(I) complex CuBrL as two colorless crystal morphs, i.e., green-emitting and yellow-emitting .

Enhancing Phosphorescence through Rigidifying the Conformation to Achieve High-Efficiency OLEDs by Modified PEDOT.

Bis(diphenylphosphinomethyl)phenylphosphine (dpmp)-supported PtAu heterotrinuclear complexes [PtAu(dpmp)(C≡CPh)](ClO) (), [PtAu(dpmp)(DEBf)(C≡CPh)](ClO) (), and [PtAu(dpmp)(DECz)(C≡CPh)](ClO) () were prepared and used in organic light-emitting diodes (OLEDs) as a new class of light emitters, where DEBf = dibenzofuran-4,6-diacetylide and DECz = 3,6-di--butylcarbazole-1,8-diacetylide. Although the flexible structure of PtAu complex (λ = 503 nm, Φ < 0.1%) results in weak photoluminescence in fluid CHCl, complexes (λ = 585 nm, Φ = 4.

Neutrophil-To-Lymphocyte Ratio Predicted Long-Term Chemotherapy Benefits In Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer Patients Without Sensitive Mutations.

Purpose: To investigate the predictive capability of clinical parameters for long-term chemotherapy benefits among stage IIIB-IV non-squamous non-small cell lung cancer (NSCLC) patients without sensitive mutations.

Patients And Methods: We investigated the clinical features of 206 stage IIIB-IV non-squamous NSCLC patients without sensitive mutations and assessed their predictive value for disease control rate (DCR) at 6 and 12 months post-treatment.

Results: Seventy-two patients received docetaxel and platinum-based chemotherapy while 134 received pemetrexed and platinum-based chemotherapy.

suppresses tumor growth and metastasis in nasopharyngeal carcinoma by repressing PI3K/AKT signaling pathway via interaction with Integrin β1 and Merlin.

Deletion of Chromosome 3p is one of the most frequently detected genetic alterations in nasopharyngeal carcinoma (NPC). We reported the role of a novel 3p26.3 tumor suppressor gene (TSG) in NPC.

Aggregation-induced emission enhancement and reversible mechanochromic luminescence of quinoline-based zinc(ii)-Schiff base complexes.

Three quinoline-based zinc(ii)-Schiff base complexes were synthesized and characterized by X-ray crystallography. They exhibit remarkable aggregation-induced emission enhancement (AIEE) in acetonitrile/diethyl ether mixtures due to the conversion of weak luminescence in homogeneous solution into strong emission in the nano-aggregated phase after increasing the fractions of diethyl ether. Interestingly, the AIEE performance can be significantly promoted by joining the two quinoline units through an alkoxy chain.

Correction: Targeting CDH17 Suppresses Tumor Progression in Gastric Cancer by Downregulating Wnt/β-Catenin Signaling.

[This corrects the article DOI: 10.1371/journal.pone.

Stimuli-responsive metal-organic supercontainers as synthetic proton receptors.

We demonstrate a proof-of-concept design of a new platform for proton recognition and modulation. The new proton receptors are derived from a unique class of synthetic supercontainers that exhibit exceptional proton binding capacity (over 50 equiv.) and intriguing proton-dependent fluorescent switching behavior.

Sensitive and selective urinary 1-hydroxypyrene detection by dinuclear terbium-sulfonylcalixarene complex.

A new sulfonylcalix[4]arene-based dinuclear terbium molecular container (1) was conveniently synthesized and utilized as a fluorescence probe for the detection of a well-known biomarker 1-hydroxypyrene (1-OHP), which is used for the evaluation of polycyclic aromatic hydrocarbons (PAHs). The sulfonylcalix[4]arene ligand could not only serve as an efficient antenna ligand to promote the ligand-to-metal energy transfer but also provide a suitable cavity to accommodate 1-OHP. Promising fluorescence quenching effects were well established during the titration of the compound 1 with 1-OHP, and these effects were due to the enhancement in the host-guest intermolecular charge transfer and the decrease in the ligand-to-metal energy transfer after the formation of the stable host-guest complex.

RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-κB Signaling and MMP1 Expression.

Esophageal squamous cell carcinoma (ESCC), a major histologic subtype of esophageal cancer, is increasing in incidence, but the genetic underpinnings of this disease remain unexplored. The aim of this study is to identify the recurrent genetic changes, elucidate their roles and discover new biomarkers for improving clinical management of ESCC. Western blotting and immunohistochemistry were performed to detect the expression level of RHCG.

FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma.

Frizzled (FZD) proteins are receptors for secreted WNT proteins and play a critical role in the malignant progression of various cancers. However, the role of human FZD family members in esophageal squamous cell carcinoma (ESCC) was rarely investigated. In this study, we found that the gene was the most commonly up-regulated member in ESCC cell lines compared with other .

Metal Complexes with a Hexadentate Macrocyclic Diamine-Tetracarbene Ligand.

A hexadentate macrocyclic N-heterocyclic carbene (NHC) ligand precursor (HL)(PF) containing four benzimidazolium and two secondary amine groups, has been synthesized and characterized. Coordination chemistry of this new macrocyclic diamine-tetracarbene ligand has been studied by the synthesis of its Ag(I), Au(I), Ni(II), and Pd(II) complexes. Reactions of (HL)(PF) with different equiv of AgO result in Ag(I) complexes [Ag(HL)](PF) (1) and [Ag(HL)](PF) (2).

Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma.

Cancer-associated fibroblasts (CAFs) are believed to influence tumor behavior and clinical outcomes. We previously showed that conditioned medium (CM) from CAFs induces proliferation and motility of esophageal squamous cell carcinoma (ESCC) cells. Here, we investigated the molecular mechanisms by which the CAF-secreted proteins induce ESCC development and progression.

Photoluminescence and electroluminescence of cationic PtAu heterotrinuclear complexes with aromatic acetylides.

Cationic PtAu heterotrinuclear complexes [PtAu(dpmp)(C[triple bond, length as m-dash]CR)] (dpmp = bis(diphenylphosphinomethyl)phenylphosphine, R = aryl) of aromatic acetylides were prepared. The PtAu structures are supported through doubly bridging dpmp and stabilized by a significant Pt-Au interaction. They are highly phosphorescent in fluid CHCl solution (Φ = 23.

Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma.

Non-CG methylation has been associated with stemness regulation in embryonic stem cells. By comparing differentially expressed genes affected by non-CG methylation between tumour and corresponding non-tumour tissues in oesophageal squamous cell carcinoma (OSCC), we find that Integrin α7 (ITGA7) is characterized as a potential cancer stem cell (CSC) marker. Clinical data show that a high frequency of ITGA7 cells in OSCC tissues is significantly associated with poor differentiation, lymph node metastasis and worse prognosis.