Publications by authors named "Li-Xue Xuan"
Background: Xuefu Zhuyu Decoction (XFZYD), a well-known traditional Chinese medicine prescription, has been widely used to treat traumatic brain injury (TBI). However, the underlying mechanisms involved in XFZYD therapy remain unclear.
Aim Of The Study: We explored new therapeutic targets of XFZYD in TBI by the tsRNA-sequencing (tsRNA-seq) method.
[Clinical analysis of intraoperative radiotherapy in breast-conserving surgery of early breast cancer].
Zhonghua Yi Xue Za Zhi
December 2013
Objective: To evaluate the safety and feasibility of intraoperative radiotherapy during breast-conserving surgery instead of whole breast radiotherapy in early breast cancer patients.
Methods: From July 2008 to December 2012, 36 early breast cancer patients underwent breast-conserving surgery plus interoperative radiotherapy on a Mobetron 1000 mobile electron accelerator. Postoperative recurrence and metastases, complications and cosmetic outcomes were recorded and analyzed.
Article Synopsis
- The study classified breast cancer into four molecular subtypes based on immunohistochemical tests for ER, PR, and HER-2 and aimed to analyze their clinical features.
- Among 408 patients, the majority had the Luminal A subtype, while Basal-like subtype showed lower lymph node metastases, and HER-2 subtype had fewer younger patients.
- The results indicated that Luminal A had the highest 5-year overall survival rate (89.83%) and lower recurrence/metastasis rates compared to other subtypes, highlighting the need for individualized treatment approaches.
Article Synopsis
- The study aimed to compare the clinical characteristics and outcomes of triple-negative (TN) breast cancer patients with those of non-triple-negative (NTN) patients, analyzing data from 408 cases.
- TN patients were generally younger and had larger tumors but exhibited a higher rate of local recurrence and metastasis, particularly to the lungs, compared to NTN patients.
- The findings indicated that TN patients had significantly lower overall and disease-free survival rates, highlighting the need for tailored treatment strategies for those diagnosed with TN breast cancer.
[The clinical detection of breast cancer by spectrum method].
Guang Pu Xue Yu Guang Pu Fen Xi
November 2008
Breast cancer is one of the most frequently encountered malignant tumors of women. Early detection can save lives successfully. A safe, effective detection method is needed.
View Article and Find Full Text PDF[Clinicopathologic analysis of primary pure squamous cell carcinoma of the breast].
Zhonghua Zhong Liu Za Zhi
November 2004
Objective: To analyze the clinicopathologic characteristics and treatment method for primary pure squamous cell carcinoma of the breast.
Methods: Twelve patients with primary squamous cell carcinoma of the breast pathologically confirmed were retrospectively reviewed. The clinical characteristics, diagnosis, treatment and prognosis were analyzed.