Publications by authors named "Li-Xian Deng"
The genus Microbacterium in the phylum Actinomycetota contains over 100 species to date that little is known about their bioactive metabolites production. In this study, a mangrove sediment-derived strain B2969 was identified as a novel type strain within the genus Microbacterium due to the low 16S rRNA gene sequence similarity (< 99%), and low overall genome relatedness indices (ANI, 75.4%-79.
View Article and Find Full Text PDFBackground: Diabetic kidney disease (DKD) represents the primary aetiological factor in end-stage renal disease, wherein lipid metabolism disorders contribute to the progression of DKD. Baicalin, a composition from Scutellaria baicalensis, has exhibited the potential to mitigate lipid metabolism disorders of DKD, but the precise mechanisms remain unclear.
Methods: High-fat-diet (HFD)/streptozotocin (STZ)-induced DKD mouse model was established to appraise the effects of baicalin on renal function, dyslipidemia, and renal ectopic lipid deposition.
Article Synopsis
- Surface plasmon resonance (SPR) is an advanced optical method used to study interactions between molecules, making it valuable in research.
- The growing focus on traditional Chinese medicine (TCM) has highlighted the challenges of identifying its active components and their interactions.
- This review outlines the principles of SPR and its applications in analyzing TCM's active components, offering both historical context and new insights.
[Expressions of aquaporin-1 on peritonea in hepatic cirrhotic rats with ascites].
Zhonghua Yi Xue Za Zhi
April 2005
Objective: To investigate the changes of aquaporin (AQP-1) expressions on peritonea in liver cirrhotic rats with ascites, and to study the correlation between AQP-1 expressions and ascites form.
Methods: 32 healthy Sprague-Dawley (SD) rats were divided into two groups randomly, 20 rats were used to produce liver cirrhotic models induced with phenobarbitol sodium and CCl(4). The distribution and protein expressions of AQP-1 on the rats' peritonea were measured with immunohistochemistry assay, and the expressions of APQ-1 mRNA were tested with relative GAPDH quantitative RT-PCR.