Publications by authors named "Li-Xia Jin"
Article Synopsis
- This study investigates the role and importance of CALU in various cancers, primarily focusing on its impact on tumor progression and treatment resistance, especially in breast cancer.
- Researchers analyzed CALU expression and its link to patient outcomes across multiple cancer types, utilizing various databases and experimental methods.
- Findings showed that higher CALU levels are associated with worse prognoses, driven by genomic changes, and CALU plays a significant role in promoting epithelial-mesenchymal transition (EMT) in both cancer cells and cancer-associated fibroblasts (CAFs).
The prevalence of chronic kidney disease(CKD) increases year by year and has become a highly prevalent disease, seriously affecting the quality of life of patients and bringing heavy family burden. There are many diseases causing CKD, including va-rious primary and secondary glomerulonephritis, renal tubular injury, and renal vascular lesions. Although routine medical treatment for CKD can alleviate the clinical symptoms to a certain extent, it is sometimes difficult to prevent the progression of CKD.
View Article and Find Full Text PDFBackground: Bletilla striata is a traditional Chinese medicine used to treat hemorrhage, scald, gastric ulcer, pulmonary diseases and inflammations. In this study, we investigated bioactivity of the effective fraction of B. striata (EFB) in reducing the inflammatory cytokine production induced by water or organic extracts of PM.
View Article and Find Full Text PDFThe anti-Staphylococcus aureus activity of the phenanthrene fraction from fibrous roots of Bletilla striata.
BMC Complement Altern Med
November 2016
Background: Bletillae Rhizoma, the tuber of Bletilla striata, has been used in Chinese traditional medicine to treat infectious diseases. Chemical studies indicated that phenanthrene was one of the most important components of the herb, with a broad spectrum of antibiotic activity against Gram-positive bacteria. The objective of this study was to further characterize the antibacterial activity of the phenanthrene fraction from the fibrous root of the pseudobulb of B.
View Article and Find Full Text PDF[Protoplasts isolation, purification and plant regeneration of Pinellia cordata].
Zhongguo Zhong Yao Za Zhi
November 2014
The main factors which affected the isolation, purification and cultivation of Pinellia cordata protoplasts from leaves were studied. The results indicated that the optimum enzyme solution for P. cordata leaves was 13% CPW + 1.
View Article and Find Full Text PDF[A seroepidemiological study on human plague in areas around the Qinghai Lake].
Zhonghua Liu Xing Bing Xue Za Zhi
September 2006
[Study on the genotyping and microevolution of Yersinia pestis in the Qinghai-Tibet Plateau].
Zhonghua Liu Xing Bing Xue Za Zhi
May 2006
Objective: To study the distribution of genomovars and microevolution of Yersinia pestis in the Qinghai-Tibet Plateau.
Methods: Primer pairs targeting the twenty-two different regions(DFRs) were designed for detecting the presence or deletion of each DFR in 297 strains isolated from the Qinghai-Tibet Plateau.
Results: 9 genomovars, i.
Genetic variations in the pgm locus among natural isolates of Yersinia pestis.
J Gen Appl Microbiol
February 2005
Article Synopsis
- * A specific gene related to a two-component regulatory system became a pseudogene in biovar Orientalis due to a deletion, while remaining intact in other biovars; additionally, some strains retained a transmembrane helix not found in others due to an 18 bp deletion.
- * Unique insertion patterns of IS100 and IS285 elements in certain strain foci suggest that these strains belong to an older lineage of Y. pestis, contributing to the stability and distinct genetic characteristics of the pgm