Repairing of recurrent leg ulcer induced by hydroxyurea with posterior tibial artery perforator propeller flap: Case report.

Introduction And Importance: Hydroxyurea is a cytotoxic drug commonly used to treat various myeloproliferative disorders. However, prolonged oral administration of this drug may trigger skin side effects and ulcers. There are few clinical reports on treating leg ulcers caused by hydroxyurea and even fewer clinical reports on managing recurrent ulcers after treatment.

Estimating intrafraction tumor motion during fiducial-based liver stereotactic radiotherapy via an iterative closest point (ICP) algorithm.

Background: Tumor motion may compromise the accuracy of liver stereotactic radiotherapy. In order to carry out a precise planning, estimating liver tumor motion during radiotherapy has received a lot of attention. Previous approach may have difficult to deal with image data corrupted by noise.

Systematic screen with kinases inhibitors reveals kinases play distinct roles in growth of osteoprogenitor cells.

Cancer treatment-related bone loss has become growing problematic, especially in breast and prostate cancer treated with hormone/endocrine therapy, chemotherapy and radiotherapy. However, bone loss caused by targeted therapy in cancer patients is largely unknown yet. In present study, a kinase inhibitors screen was applied for MC3T3-E1, a murine osteoprogenitor cell line, and seven kinase inhibitors (GSK1838705A, PF-04691502, Dasatinib, Masitinib, GDC-0941, XL880 and Everolimus) were found to suppress the cell viability with dose- and time-dependent manner.

Roles of microRNA-206 in osteosarcoma pathogenesis and progression.

Background And Aims: MicroRNA-206 has proven to be down-regulated in many human malignancies in correlation with tumour progression. Our study aimed to characterize miR-206 contributions to initiation and malignant progression of human osteosarcoma.

Methods: MiR-206 expression was detected in human osteosarcoma cell line MG63, human normal osteoblastic cell line hFOB 1.

[Early clinical research of total hip arthroplasty for the treatment of old acetabular fractures].

Objective: To analyze the early clinical effects of total hip arthroplasty(THA) for the treatment of old acetabular fractures.

Methods: From January 2007 to June 2010, thirteen patients with old acetabular fractures were reviewed, including 10 males and 3 females. Ten patients were treated with internal fixation and conservative treatment had been used in three patients.

[Prognostic significance of hidden blood loss in total hip arthroplasty (THA)].

Objective: To explore the prognostic significance of hidden blood loss in total hip arthroplasty.

Methods: From May 2008 to July 2009, Harris hip score was used to evaluate the functions of 71 patients undergoing single side total hip arthroplasty (including 47 males and 24 females with a mean age of 68.3 years, ranged from 48 to 75 years).

[Early rehabilitation after simultaneously bilateral total knee arthroplasty].

Objective: To investigate the principle and methods of preoperative and postoperative rehabilitation for simultaneous bilateral total knee arthroplasty.

Methods: From January 2005 to June 2008, 72 patients (144 knees) were reviewed in the study, including 33 males and 39 females, ranging in age from 46 to 78 years, with an average age of 69 years. There were 54 patients with osteoarthritis, 17 patients with RA, and 1 patient with traumatic osteoarthritis, including 10 cases (15 knees) of fixed varus deformity more than 30 degree and 6 cases (8 knees) of fixed vagus deformity more than 15 degree.

[Complications of bipolar hemiarthroplasty for the treatment of unstable intertrochanteric fractures in the elderly].

Objective: To analyze the complications of bipolar hemiarthroplasty for the treatment of intertrochanteric fractures.

Methods: From Jan. 2004 to Dec.

[Concentration measurement of the OPG and sRANKL of peripheral blood among normal healthy people].

Objective: To measure the concentration of osteoprotegerin (OPG) and receptor activator of NF-kappaB ligand (sRANKL) in peripheral blood among normal healthy people and investigate the relationship pf the concentration with age and sex.

Methods: The peripheral blood samples of 220 normal healthy people (included 108 males and 112 females, aged from 35 to 70) were collected in the morning. The OPG and sRANKL concentration of blood serum were measured by ELISA.

Improved citation status of World Journal Gastroenterology in 2004: Analysis of all reference citations by WJG and citations of WJG articles by other SCI journals during 1998-2004.

Aim: To determine the citation status in 2004 and the citation trend of WJG by analyzing all articles cited by WJG and all WJG articles cited by SCI journals during 1998-2004.

Methods: The total number of published articles and reference citations in WJG, authors' self-citations, WJG's self-citations, citations of WJG articles by SCI journals and inappropriate citations in WJG during 1998-2004 were statistically analyzed. Data on self-citations of the articles published between 1998 and August 2004 (Issues 1-16) were from ISI SCI-E, and data on self-citations of articles published after August 2004 (Issues 17-24) were from the WJG Editorial Office.