Publications by authors named "Li-Weng Li"
Hub genes for early diagnosis and therapy of adamantinomatous craniopharyngioma.
Medicine (Baltimore)
September 2022
Background: Adamantinomatous craniopharyngioma (ACP) is a subtype of craniopharyngioma, a neoplastic disease with a benign pathological phenotype but a poor prognosis in the sellar region. The disease has been considered the most common congenital tumor in the skull. Therefore, this article aims to identify hub genes that might serve as genetic markers of diagnosis, treatment, and prognosis of ACP.
View Article and Find Full Text PDFHub biomarkers for the diagnosis and treatment of glioblastoma based on microarray technology.
Technol Cancer Res Treat
November 2021
Article Synopsis
- Glioblastoma (GBM) is a common and aggressive brain tumor that primarily damages brain tissue, leading to fatal outcomes; this study aimed to uncover gene targets for GBM diagnosis and treatment using bioinformatics.
- Researchers utilized public data from patients with GBM to identify differentially expressed genes (DEGs), where they found 130 DEGs and narrowed it down to 10 hub genes of interest via platforms like GEPIA and GEO2R.
- The study revealed that four specific hub genes were significantly overexpressed in GBM patients compared to controls, suggesting their potential as biomarkers for future diagnostics and therapies for GBM.