Mycobacterium vaccae alleviates allergic airway inflammation and airway hyper-responsiveness in asthmatic mice by altering intestinal microbiota.

Host immunity can influence the composition of the gut microbiota and consequently affect disease progression. Previously, we reported that a Mycobacterium vaccae vaccine could ameliorate allergic inflammation in asthmatic mice by regulating inflammatory immune processes. Here, we investigated the anti-inflammatory effects of M.

Aerosol inhalation of ameliorates airway structural remodeling in chronic asthma mouse model.

Airway remodeling is accepted to be a determining component within the natural history of asthma. Nebulized inhalation of () has a protective effect on asthmatic mice. However, little is known regarding the effect of on airway structural remodeling in asthmatic mice.

[Paracentesis with albumin and dextran treatment for advanced schistosomiasis ascites].

Forty-two cases of advanced schistosomiasis with massive ascites were treated with paracentesis and infusion of dextran and albumin. The effective rate was 100%. No abdominal wall hematoma, internal bleeding and visceral injury except 2 cases of mild abdominal congestion.

[Investigation on the gene expression pattern in cervical squamous cell carcinoma of uygur].

Objective: To investigate the differentially expressed gene in cervical squamous cell carcinoma of uygur and normal cervical tissue using gene chip.

Method: Gene chips containing 2,048 human genes were used to investigate the gene expression pattern of 3 samples of cervical cancer.

Result: By applying this gene chip we identified 64 differentially expressed genes in all 3 clinical cervical cancer samples, and we further identified 53 upregulated and 11 downregulated genes for functional analysis.

[Study of the interactions between diorganotin (IV) complexes of 1,3-dimethyl-4-acetyl-5-pyrazolone and mononucleotides and DNA].

Aim: The interactions between diorganotin (IV) complexes of 1,3-dimethyl-4-acetyl-5-pyrazolone (HL1) and mono-nucleotides together with DNA near physiological condition were investigated.

Methods: The mode of action of the diorganotin (IV) complexes with mononucleotides and DNA under different conditions and different times were investigated by high resolution NMR technology and UV spectra.

Results: The interaction of [(L1)2SnEt2] with AMP was shown to result in significant change of chemical shift of H(8), H(2) and 31P of AMP.