Publications by authors named "Li-Sha He"

Article Synopsis
  • - Atherosclerosis (AS) is a major health issue linked to various cardiovascular diseases, with increasing rates of morbidity and mortality, yet treatments remain inadequate.
  • - Key factors in the development of AS include endothelial cell dysfunction, inflammation, and oxidative stress, with endothelial dysfunction being a critical early event in the disease's progression.
  • - Flavonoids from herbal medicines, particularly quercetin and naringenin, show promise in preventing endothelial dysfunction by combating oxidative stress, indicating their potential in treating AS.
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Rhizoma phragmitis is a common Chinese herbal medicine whose effects are defined as 'clearing heat and fire, promoting fluid production to quench thirst, eliminating irritability, stopping vomiting, and disinhibiting urine'. During the Novel Coronavirus epidemic in 2020, the Weijing Decoction and Wuye Lugen Decoction, with Rhizoma phragmitis as the main herbal component, were included in The Pneumonia Treatment Protocol for Novel Coronavirus Infection (Trial Version 5) due to remarkable antiviral effects. Modern pharmacological studies have shown that Rhizoma phragmitis has antiviral, antioxidative, anti-inflammatory, analgesic, and hypoglycemic functions, lowers blood lipids and protects the liver and kidney.

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Ethnopharmacological Relevance: Diabetes is a common, complex, chronic metabolic disease. A randomized, double-blind, placebo-parallel controlled clinical study has shown that Gegen Qinlian Decoction (GQD) can reduce glycosylated hemoglobin in type 2 diabetes mellitus (T2DM) intestinal damp-heat syndrome patients in a dose-dependent manner.

Aim: To explore the pathogenesis of T2DM intestinal damp-heat syndrome and the therapeutic effect of GQD from the perspective of exosomal microRNA (miRNA).

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Background: Retinoblastoma is the most common intraocular malignancy occurring in children. It can metastasize to the regional lymph nodes, central nervous system and distant organs usually the bones and bone marrow and very rarely to the soft tissue. Here, we report a case of unilateral retinoblastoma in a 4-year-old girl accompanied by a large metastasis of the parotid and submandibular glands that developed about 6 months previously and gradually increased in size 5 months after enucleation of the left eye.

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Incorrect author affiliation and the typo in acknowledgement section were found in the original publication. The correct author affiliations and acknowledgments are given here.

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Introduction: Prevention of the rapid growth in incidence of type 2 diabetes (T2DM) is a big challenge for clinicians. In China, many trials have indicated that Tianqi capsule, which contains several Chinese herbal medicines as part of a large healing system called traditional Chinese medicine, could decrease the incidence of T2DM. The review assessed the effectiveness of Tianqi capsule in prevention of T2DM.

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The clinical therapeutics of traditional Chinese medicine (TCM) constitutes a complicated process which involves theory, diagnosis, and formula prescription with specific herbal dosage. Zhang Zhong-Jing's classic work, Treatise on Febrile and Miscellaneous Diseases, has been influencing TCM practice for almost 2000 years. However, during this extended period of time in Chinese history, the Chinese weight measurement system experienced noticeable changes.

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Article Synopsis
  • The rising rates of diabetes mellitus (DM) are presenting a significant public health challenge, prompting the exploration of traditional Chinese medicine (TCM) as a potential treatment option.
  • The review highlights innovative strategies for TCM in managing DM, focusing on principles such as combining symptoms, syndromes, and disease; emphasizing methods like heat-clearing and blood circulation; and utilizing specific herbs and formulas aligned with TCM and modern medicine.
  • The importance of proper dosage in TCM is underscored, as it significantly influences treatment effectiveness and the overall management of diabetes.
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