Publications by authors named "Li-Rui Xing"
Background: LCZ696 is a novel neuroendocrine inhibitor that has been widely used in heart failure (HF). However, its advantage over other neuroendocrine inhibitors, such as angiotensin-converting enzyme inhibitors (ACEis) and angiotensin-receptor blockers (ARBs) has not been fully elucidated. This study aimed to provide the latest evidence regarding the efficacy and safety of LCZ696 as compared to other ACEis and ARBs with regards to the treatment of HF.
View Article and Find Full Text PDFScreening of pesticide residues in Traditional Chinese Medicines using modified QuEChERS sample preparation procedure and LC-MS/MS analysis.
J Chromatogr B Analyt Technol Biomed Life Sci
September 2020
Article Synopsis
- - A new method combining UHPLC-MS/MS and modified QuEChERS was developed for simultaneously detecting 108 pesticide residues in Traditional Chinese Medicines (TCMs), showing high sensitivity and good recovery rates (over 92% for most pesticides).
- - The analysis of 39 real TCM samples revealed that 92.3% contained pesticide residues, with tebuconazole found across all samples at acceptable levels, while paclobutrazol exceeded the maximum allowed limits in some instances.
- - Given the lack of regulations on pesticide residue limits for TCMs in China, the study suggests that it is crucial to establish appropriate regulatory standards to ensure safety.
The increased attention to luminescent copper(I) complexes, mostly mononuclear and dinuclear ones, in the past few years was mainly due to the new pathways established in the intersystem crossing (ISC) for highly efficient singlet/triplet harvesting, which showed great potential in light-emitting devices. Governing the photophysical processes of planar cyclic trinuclear complexes is more challenging owing to the rich intra- and intermolecular metal-metal interactions involved, but new opportunities also accompany this. Herein reported is a hidden route to the ultra-long-lived, highly efficient phosphorescence of cyclic trinuclear two-coordinate Cu-pyrazolate complexes through pushing the unfavorable metal-to-ligand charge transfer events to the high-lying ISC pathways.
View Article and Find Full Text PDFArticle Synopsis
- Verticillium dahliae is a pathogen causing wilts in plants, leading to severe defoliation, with its underlying mechanisms still not fully understood.
- Research involved various methods like genome sequencing and gene analysis, revealing the importance of specific genes (VdDf) in the defoliating strains of V. dahliae.
- Notably, compounds like N-lauroylethanolamine (NAE) are linked to defoliation, suggesting that VdDfs influence the production of secondary metabolites responsible for the defoliation phenotype by affecting hormone sensitivity and plant responses.