Publications by authors named "Li-Rong Lian"
Article Synopsis
- - Taurine is a naturally occurring substance that plays a role in many bodily functions and may predict lung cancer development. Elevated levels of taurine were found in lung cancer patients, but the relationship between these levels and cancer progression is unclear.
- - The study investigated taurine's impact on lung cancer using mouse models and patient tissue samples, aiming to find new treatment strategies by exploring taurine's mechanisms.
- - Results showed that low doses of taurine and taurine drinks promoted tumor growth, while higher doses reduced this effect. The research suggests that taurine influences lung cancer progression through immune responses and inflammatory mechanisms, with related effects changing as patients age.
Background: Chronic diseases such as tumors and autoimmune disorders are closely linked to metabolism and immunity and require conflicting treatment methods. AMPK can regulate cell growth and inflammation through energy metabolism. Sinomenine is a compound extracted from the traditional Chinese herb sinomenium acutum (Thunb.
View Article and Find Full Text PDFArticle Synopsis
- Researchers used bioinformatics techniques to identify key genes related to the immune environment in hepatocellular carcinoma (HCC) and developed an immune risk prognostic model (IRPM) to evaluate patient survival outcomes.
- The study involved analyzing HCC tissue transcriptome data to discover immune-related genes linked to overall survival, and a Cox regression analysis was used to build the prognostic model.
- Findings indicated that patients classified in the high-risk group had poorer outcomes, and immune-related hub genes were associated with the effectiveness of certain chemotherapy drugs, suggesting potential applications in improving HCC treatment strategies.*