Labial inverse dilaceration of bilateral maxillary central incisors: A case report.

Background: Dilaceration is a rare dental developmental anomaly characterized by an abrupt deviation along the longitudinal axis of the root in which an angulation forms between the root and the crown. Here, we report on dilacerated bilateral maxillary central incisors in mixed dentition.

Case Summary: A 10-year-old girl presented with a chief complaint of unerupted central incisors.

Self-reported and genetically predicted effects of coffee intake on rheumatoid arthritis: Epidemiological studies and Mendelian randomization analysis.

Background And Aims: Causal research concerning coffee intake and rheumatoid arthritis (RA) risk is controversial. The objective of this study was to further explore the causal relationship between coffee intake and RA risk.

Methods: The 4,310 participants from NHANES 2003-2006 were included in an epidemiological study to assess the association between coffee intake and RA by weighted multivariate logistic regression.

Cyclic Adenosine Monophosphate-Enhanced Calvarial Regeneration by Bone Marrow-Derived Mesenchymal Stem Cells on a Hydroxyapatite/Gelatin Scaffold.

Cyclic adenosine monophosphate (cAMP) plays a significant role in inducing new bone formation by mediating various signal pathways. However, cAMP, combined with biomaterials, is rarely investigated to reconstruct calvarial defects. In this study, cAMP was loaded into a hydroxyapatite (HA)/gelatin (Gel) construct and implanted into critical skull defects in rats to evaluate the potential for enhancing skull regeneration.

Minimally invasive video-assisted thyroidectomy for the early-stage differential thyroid carcinoma.

Background: Minimally invasive video-assisted thyroidectomy (MIVAT), the modified Miccoli's thyroid surgery, is the most widespread minimally invasive technique and has been widely used for treatment of thyroid disease. This study aimed to verify the potential benefits of the modified Miccoli's thyroid surgery, determine the feasibility of the MIVAT for early-stage differential thyroid carcinoma and evaluate the likelihood of the surgical method as a standard operation for early malignant thyroid carcinoma.

Methods: A total of 135 patients were retrospectively compared which included two groups of patients: the first group underwent the conventional thyroidectomy; the other group underwent MIVAT.

Mouse model of plasma cell mastitis.

Background: Plasma cell mastitis is distinct from the common form of mastitis and clinically resembles breast carcinoma. The lesion occurs in non-lactating young women, and the incidence rate is rising. Surgical resection is the main treatment, but cannot prevent recurrence of the disease.

[Effects of rhubarb on intestinal flora and bacterial translocation in rats with sepsis].

Objective: To investigate the effects of rhubarb on intestinal flora and bacterial translocation in septic rats.

Methods: One hundred and four Sprague-Dawley (SD) rats were randomly divided into normal control group, burn group, sepsis group, and sepsis with rhubarb treatment group. All the animals except those in the normal control group were given 30% total body surface area (TBSA) III degree burn on their back followed by endotoxin challenge intraperitoneally in a dose of 20 mg/kg 24 hours after the burn injury.

[Influence of broad-spectrum antibiotics on the gut microflora in sepsis in rats].

Objective: To study the influence of broad-spectrum antibiotics on intestinal microecology in septic rats.

Methods: Fifty-six Sprague-Dawley (SD) rats were randomly divided into normal control, burn and sepsis group. Rats in the latter two groups received 30% total body surface area (TBSA) III degree burns on back followed by an injection of endotoxin in a dose of 20 mg/kg 24 hours later.

[Selective action of broad-spectrum antibiotics on intestinal flora in sepsis in rats].

Objective: To investigate the selective effect of broad-spectrum antibiotics on the intestinal flora in sepsis in rats.

Methods: Fifty-six SD rats were randomly divided into normal control group, scald group [before ceftriaxone sodium (rocephin) treatment group], scald group with 3 days of rocephin treatment, scald group with 9 days of rocephin treatment, and sepsis group (before rocephin treatment group), sepsis group with 3 days of rocephin treatment, and sepsis group with 9 days of rocephin treatment. All the animals were incurred with 30% III degree burns on their back followed by endotoxin challenge with a dose of 20 mg/kg 24 hours after the burn injury.