Antibiotic Resistance Determinants and Virulence Factors of Hypervirulent and Carbapenem Non-Susceptible Pseudomonas aeruginosa.

Background: The aim was to investigate the distribution of antibiotic resistance determinants and virulence factors in a group of carbapenem non-susceptible Pseudomonas aeruginosa (P. aeruginosa).

Methods: From March 2018 to May 2019, a total of 98 P.

Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells and by activating AMP-activated protein kinase.

Aim: To investigate the effect of metformin on activated hepatic stellate cells (HSCs) and the possible signaling pathways involved.

Methods: A fibrotic mouse model was generated by intraperitoneal injection of carbon tetrachloride (CCl) and subsequent treatment with or without metformin. The level of fibrosis was detected by hematoxylin-eosin staining, Sirius Red staining, and immunohistochemistry.