Publications by authors named "Li-Pei Luo"
Article Synopsis
- The study investigates HPV prevalence among females in Southern China prior to the introduction of mass HPV vaccination, highlighting the need for baseline data on the infection rates.
- Conducted between 2012 and 2018, it analyzed cervical screening results from 214,715 women, revealing an overall HPV prevalence of 18.71% and a downward trend over the years observed.
- The research identified peak HPV infection rates in women under 21, with high-risk types being HPV52, HPV16, and HPV58, while low-risk types included HPV81 and HPV6, emphasizing the importance of targeting younger demographics for vaccination.
Label-free fluorescent and electrochemical biosensors based on defective G-quadruplexes.
Biosens Bioelectron
October 2018
Abnormal levels of guanine closely associated with plenty of diseases are usually used as a biomarker for clinical diagnosis. In order to detect guanine and its derivatives accurately, in this paper, a defective G-quadruplex (DGQ) containing a G-vacancy at one of its G-quartet layers, and two kinds of G-quadruplex specific indicators including thioflavine T (ThT) and hemin were used for constructing a fluorescent and an electrochemical biosensor, respectively. In brief, a G-rich DNA probe is designed to form either hairpin or DGQ structure.
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