Neuropeptide natalisin regulates reproductive behaviors in Spodoptera frugiperda.

Natalisin (NTL) is a conserved neuropeptide, only present in insects, that has been reported to regulate their sexual activity. In this study, we investigated the involvement of NTL in the reproductive behaviors of a major invasive pest, Spodoptera frugiperda. We identified NTL precursor-encoded transcripts, and evaluated their transcript levels in different stages and tissues of S.

Genomics, transcriptomics, and peptidomics of the greater wax moth Galleria mellonella neuropeptides and their expression in response to lead stress.

Neuropeptides are crucial in regulation of a rich variety of developmental, physiological, and behavioral functions throughout the life cycle of insects. Using an integrated approach of multiomics, we identified neuropeptide precursors in the greater wax moth Galleria mellonella, which is a harmful pest of honeybee hives with a worldwide distribution. Here, a total of 63 and 67 neuropeptide precursors were predicted and annotated in the G.

Feasibility analysis of rapid gene detection using intraoperative frozen tissues: comparison of intraoperative frozen tissues with paraffin-embedded tissues in epidermal growth factor receptor gene mutation detection of lung adenocarcinoma.

Background: Epidermal growth factor receptor (EGFR) is the driver gene with the highest frequency of mutations in lung adenocarcinoma and can guide the development of targeted therapies. The detection of routine gene mutations must be performed after the preparation of paraffin samples in a standard polymerase chain reaction (PCR) laboratory, which is time-consuming. The Idylla™ EGFR fully automatic PCR system for rapid detection requires no special detection environment and completes the process in only 2.

A comparison of capillary electrophoresis and next-generation sequencing in the detection of immunoglobulin heavy chain H and light chain κ gene rearrangements in the diagnosis of classic hodgkin's lymphoma.

This study aimed to compare the application value of capillary electrophoresis and next-generation sequencing for immunoglobulin (IG) gene rearrangement in the diagnosis of classic Hodgkin's lymphoma. Twenty paraffin-embedded specimens from patients with classic Hodgkin's lymphoma were screened. For gene rearrangement detection, the ABI 3500 Genetic Analyzer and ABI Ion GeneStudio S5 Plus sequencing system were used, respectively, and the results were compared.

Correction: Isostructural lanthanide-based metal-organic frameworks: structure, photoluminescence and magnetic properties.

Correction for 'Isostructural lanthanide-based metal-organic frameworks: structure, photoluminescence and magnetic properties' by Li-Lin Luo et al., Dalton Trans., 2018, 47, 925-934.

Isostructural lanthanide-based metal-organic frameworks: structure, photoluminescence and magnetic properties.

A series of the anhydrous lanthanide-based metal-organic frameworks (Ln-MOFs) were successfully synthesized under hydrothermal conditions of Ln(iii) ions with 3,4'-oxybis(benzoate) (3,4'-oba), oxalate (ox) and 1,10-phenanthroline (phen). Structural analyses revealed that they are isostructural 3D open-frameworks with the formula of [Ln(3,4'-oba) (phen)(ox)] (Ln = Sm for 1, Eu for 2, Gd for 3, Tb for 4, and Dy for 5) and the topology of {3·4·5·6}. Within the 3D structure, the [LnON] units are bridged by ox to form [Lnox] dimers and then are further connected by 3,4'-oba ligands.