Transmembrane protein 92 performs a tumor-promoting function in breast carcinoma by contributing to the cell growth, invasion, migration and epithelial-mesenchymal transition.

Objective: We try to examine the role of transmembrane protein 92 (TMEM92) in the progression of breast carcinoma (BC) and assess its prognostic value. Moreover, the effects of TMEM92 on BC cell phenotypes was explored.

Methods: The levels of TMEM92 in BC tissues were evaluated using bioinformatics analysis according to the Oncomine and The Cancer Genome Atlas databases.

Circulating obestatin levels correlate with fasting insulin and HOMA-IR but not with hypertension in elderly men.

Obestatin, encoded by the same gene as ghrelin, was first described as a physiological opponent of ghrelin. The association between circulating obestatin levels and blood pressure remains unclear. Furthermore, adequate information is non-existent regarding the older male population with hypertension.

[Effects of Ghrelin on hypertension and insulin resistance in fructose-fed rats].

Objective: To explore the effects and mechanisms of Ghrelin on hypertension and insulin resistance in fructose-fed rats.

Methods: A total of 32 male Sprague-Dawley (SD) rats were randomized into control (A) and fructose-fed groups (B). Rats in group B were fed with 10% fructose solution for 4 weeks.

Clostridium difficile infection associated with antituberculous agents in a patient with tuberculous pericarditis.

Clostridium difficile can cause pseudomembranous colitis (PMC). Antimicrobial agent exposure is a risk factor for Clostridium difficile-associated disease, whereas the use of antituberculous (anti-TB) agents is not. We herein report a case of PMC-associated with antituberculous therapy.

[Synthesis and spectral properties of L-amino acid tailed porphyrin and their zinc(II) complexes].

Three new L-amino acid tailed porphyrins and their zinc(II) complexes were synthesized by L-amino acid and 5-[o-(bromnoethoxyl)phenyl]-10,15,20-triphenyl prophyrin. FABMS, UV-Vis, IR, elemental analysis and chemical analysis were used to determine the structures of these porphyrins and their zinc complexes. The FTIR spectra (4000-400 cm(-1)) of L-amino acid tailed porphyrin and its zinc(II) complexes were measured and investigated.