Publications by authors named "Li-Kun Li"
The objective of this study was to identify methylation-driven genes and explore their prognostic value in colon adenocarcinoma (COAD). The Cancer Genome Atlas (TCGA) database was used to acquire collated COAD transcriptome gene expression matrix (containing 59,427 transcripts), transcriptome gene methylation level matrix (containing 29,602 methylated modified genes), which included 517 samples containing 41 samples of normal tissue (NT) & 476 samples of COAD, and patient clinical information files (including patient survival time, survival status, age, gender and tumor stage, etc.), for all COAD samples.
View Article and Find Full Text PDF[Transurethral columnar balloon dilation of the prostate for benign prostatic hyperplasia].
Zhonghua Nan Ke Xue
February 2021
Article Synopsis
- The study focused on the clinical effectiveness of transurethral columnar balloon dilation of the prostate (TUCBDP) for treating benign prostatic hyperplasia (BPH) based on analysis of 265 cases from 2016 to 2019.
- Results showed successful surgeries with an average operation time of about 25 minutes and minimal blood loss, resulting in significant improvements in urinary symptoms and quality of life post-surgery.
- While 20% of patients experienced some complications, such as transient urinary incontinence and infections, most issues improved with treatment, highlighting TUCBDP's suitability for elderly patients and those concerned about preserving sexual function.
Objective: To observe the effects of the glycolysis inhibitor 3-bromopyruvate (3-BrPA) on the proliferation, migration and invasive ability of prostate cancer PC-3 cells in vitro and explore the underlying mechanisms.
Methods: We cultured prostate cancer PC-3 cells in vitro and treated them with 3-BrPA at different concentrations for 24, 48 and 72 hours. Then we observed the morphological changes of the PC-3 cells under the inverted microscope.
Evaluating the effects of transgenic Bt rice cultivation on soil stability.
Environ Sci Pollut Res Int
May 2020
Insecticidal crystal (Cry) proteins produced by genetically modified rice that enter the soil via pollen dispersal, plant residues, and root exudation may disturb soil health. In the present study, we assessed the influences of transgenic Bt rice (i.e.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the effects of planting mixtures of transgenic Bt rice and its non-transgenic parent line on pest populations in southern China over two years.
- Results show that higher ratios of Bt rice decrease target pests while preserving yields, with the most effective pest control achieved with 90% or more Bt rice.
- The strategy of using seed mixtures is suggested as a way to maintain rice yields and reduce insecticide use without compromising pest control.