Publications by authors named "Li-Jun Sheng"

Article Synopsis
  • * Phaeosphaerienols A-C (1-3) are unique due to their tremulane structure featuring a 1,10-epoxide group, while their structures were determined using various scientific methods, including NMR and X-ray analysis.
  • * The isolated compounds were tested for cytotoxicity, antibacterial properties, and free radical scavenging
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Background: Fertilization failure often occurs in conventional IVF cycles, and day 1 rescue ICSI is frequently recommended. In this study, the effect of rescue ICSI on obstetrical and neonatal outcomes after a single blastocyst transfer in vitrified-warmed cycles is evaluated.

Methods: This cohort study was a retrospective analysis of 703 vitrified-warmed single blastocyst transfers and 219 singletons in the r-ICSI group compared with 11,611 vitrified-warmed single blastocyst transfers in the IVF/ICSI and 4472 singletons in the IVF/ICSI group, respectively, and patients just undergoing their first IVF treatments were included in this study.

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Previous assessments of the effectiveness of protected areas (PAs) focused primarily on changes in human pressure over time and did not consider the different human-pressure baselines of PAs, thereby potentially over- or underestimating PA effectiveness. We developed a framework that considers both human-pressure baseline and change in human pressure over time and assessed the effectiveness of 338 PAs in China from 2010 to 2020. The initial state of human pressure on PAs was taken as the baseline, and changes in human pressure index (HPI) were further analyzed under different baselines.

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  • The study aimed to determine the best warming time for transferring slow-growing embryos during frozen embryo transfer (FET) cycles.
  • It included 705 patients aged under 40, who underwent analysis of 1486 embryos, with 1366 being transferred.
  • Results showed that early warming led to a higher clinical pregnancy rate (32.5%) compared to routine warming (23.4%) for slow-growing embryos, indicating that better timing could enhance the chances of successful pregnancy.
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Meiosis is a complex process involving the expression and interaction of numerous genes in a series of highly orchestrated molecular events. Fam9b localized in Xp22.3 has been found to be expressed in testes.

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It had been suggested, after facilitating the hatching process, improved pregnancy outcomes could be attained in embryos with thick and hard zona. This study aimed to determine the effect of zona thinning on pregnancy outcomes in poor-quality frozen-thawed blastocysts. This retrospective study included 230 women (≤ 40 years) who underwent frozen embryo transfer of poor-quality blastocysts (scored < 3BB).

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The value evaluation of endangered species can provide important supports for policy-making in biodiversity conservation. We evaluated the stakeholders' preference and willingness to pay (WTP) from the perspective of stakeholders by the choice experiment method (CEM) and discussed the ecological compensation mechanism, with , a national secondary key protected plant as an example. Based on the interest demands analysis of three stakeholders, the management departments, enterprises and farmers, we measured five species attributes of , including planting area, product classification, seedling varieties, protection investment, and far-mers' income.

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Objective: This study investigated the frequency of T-helper (Th)17 lymphocytes and production of cytokine interleukin (IL)-17 in peripheral blood of patients with non-small-cell lung cancer (NSCLC) and their use as a marker of clinical value.

Methods: Sixty patients with NSCLC and 60 healthy volunteers were enrolled in the study. Flow cytometry was used to detect the frequency of Th17 lymphocytes in peripheral blood, and enzyme-linked immunosorbent assay (ELISA) was used to detect serum levels of IL-17.

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A method was established for simultaneous determination of 21 active constituents including flavanols, isoflavones, flavonols, dihydroflavones, dihydroflavonols, chalcones, pterocarpan, anthocyanidins and phenolic acids in Spatholobi Caulis by ultra fast liquid chromatography with triple quadrupole linear ion trap mass spectrometry(UFLC-QTRAP-MS/MS). Then, it was employed to analyze and evaluate the dynamic accumulation of multiple bioactive constituents in Spatholobi Caulis. The chromatographic separation was performed on a XBridge®C_(18)(4.

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A series of novel indole-based oxalamide and aminoacetamide derivatives were designed, synthesized, and evaluated for antiproliferative activities. Preliminary results revealed that compound 8g exhibited significant antiproliferative effect against PC-3, HeLa and HCT-116 cell lines. Flow cytometric analysis of the cell cycle demonstrated the compound 8g induced the cell cycle arrest at G2/M phase in HeLa cell lines.

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Genetic variation and population structure may reflect important information for invasion success of exotic plant species and thus help improve management of invasive plants. Spartina alterniflora is an invasive plant that is a major threat to the economy and environment of the coastal regions in China. We analyzed the genetic structure and diversity of six populations of S.

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  • NPS-2143, a calcium-sensing receptor (CaSR) antagonist, shows potential as an anticancer agent against gastric cancer (GC), but its specific effects had not been previously studied.
  • The study revealed that CaSR levels are elevated in GC tissues compared to normal tissues, and treatment with NPS-2143 inhibited the growth, invasion, and migration of GC cells (AGS), while promoting apoptosis.
  • Mechanistically, NPS-2143 works by decreasing key proteins in the PI3K/Akt signaling pathway and showed similar inhibitory effects as CaSR knockdown, confirming that NPS-2143 targets CaSR in its anticancer role.
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Increasingly frequent urban waterlogging disasters, which are mainly caused by the increase in impervious surfaces due to rapid urbanization, have attracted public attention. Green roofs are conducive to increasing the urban pervious surface area to control sources of runoff, which has great significance for the ecological environment. This study uses the green roof of the administrative building of Jinling Primary School in Nanjing as the study area.

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Rationale: To investigate the early and mid-term clinical outcomes of the modified cone reconstruction in the treatment of Ebstein's anomaly (EA) which provide appropriate surgical treatment for clinical and reduce the incidence of re-operation and valve replacement.

Patient Concerns: Clinical data of 18 consecutive patients with EA in our hospital between May 2008 and August 2015 were analyzed retrospectively. All patients were diagnosed by echocardiography.

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Globalization increases the opportunities for unintentionally introduced invasive alien species, especially for insects, and most of these species could damage ecosystems and cause economic loss in China. In this study, we analyzed drivers of the distribution of unintentionally introduced invasive alien insects. Based on the number of unintentionally introduced invasive alien insects and their presence/absence records in each province in mainland China, regression trees were built to elucidate the roles of environmental and anthropogenic factors on the number distribution and similarity of species composition of these insects.

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Introduction: Ebstein's anomaly is a benign and stable congenital heart disease for asymptomatic patients. Despite a low incidence of Ebstein's anomaly (EA), patients' quality of life can be badly affected by EA without positive surgical intervention. Especially EA is associated with other congenital heart disease, such as the atrial septal defect, patent foramen ovale, and arterial embolism exclude other reasons, it is often considered to be the consequence of paradoxical embolism, and surgical intervention must be conducted.

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Polarization is defined as an asymmetry in the direction of vibration with respect to the direction of light propagation. Polarization information is an important component to remote sensed data, which comprises spatial, spectral, and radiation information. In optical remote sensing, polarization information supplements spectral information.

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The protection efficacy of nature reserves is a key element in achieving targets of biodiversity conservation. It is therefore very important to develop a scientific, systematic, and accurate index system for evaluating the protection efficacy of national nature reserves in China. Using methods of frequency statistics, expert consultation, analytic hierarchy process, and demonstration survey, we present a novel index system for evaluating the protection efficacy of Chinese national nature reserves for terrestrial vertebrates (excluding migratory birds) over a 10-year period.

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In the present paper, Guanting Reservoir located in Zhangjiakou City, Hebei province and Yanqing District, Beijing, was selected as the study area, and Chromophoric dissolved organic matter (CDOM) content (represented by the CDOM absorption coefficient at 440 nm, aCDOM (440)) was inverted through semi-analytical method and empirical method. The data used in this paper include the spectral data (R (λ)) collected on October 26, 2013 over Guanting Reservoir and aCDOM (λ) measured in the laboratory. A semi-analytical method (QAA-CDOM) was validated and improved accordingly.

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Agricultural biodiversity is a key part of the ecosystem biodiversity, but it receives little concern. The monoculture, environmental pollution and habitat fragmentation caused by agricultural activities have threatened agricultural biodiversity over the past 50 years. To optimize agricultural management measures for crop production and environmental protection, we reviewed the effects of agricultural activities, including cultivation patterns, plastic mulching, chemical additions and the cultivation of transgenic crops, on agricultural biodiversity.

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The optical field above water is not isotropic. It is important to study the directional reflectance properties of the optical field above water, which is useful for building water quality parameters retrieving models by remote sensing. The bidirectional reflectance distribution function above oceanic waters has been well studied.

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In this paper, an ecological vulnerability evaluation index system for the Shengli Coalfield in Xilinguole of Inner Mongolia was established, which included 16 factors in ecological sensitivity, natural and social pressure, and ecological recovery capacity, respectively. Based on the expert scoring method and analytic hierarchy process (AHP), an ecological vulnerability model was built for the calculation of the regional ecological vulnerability by means of RS and GIS spatial analysis. An analysis of the relationships between land use and ecological vulnerability was also made, and the results were tested by spatial auto-correlation analysis.

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Four field investigations were carried out in the Taihu Lake for collecting in situ observation data in Nov. 2008, Apr. 2009, May and Aug.

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  • The brown planthopper (BPH) is a significant pest affecting rice crops, prompting a study on its survival under different conditions.
  • Researchers manipulated rice plant environments to create adverse survival conditions (ASC) for BPH nymphs and identified gene responses through Solexa/Illumina sequencing.
  • The study found over 2,500 differentially expressed genes related to development and metabolism, highlighting how BPH adjusts its gene expression in response to challenges like high density and low-quality food sources.
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China is one of the origin centers of rice (Oryza sativa), with a distribution of abundant wild rice germplasm resources. Since the biosafety certificates were issued to Bt transgenic rice containing cry1Ac gene against lepidopteran pests, concerns are raised on the gene flow from transgenic rice to its wild relatives. This paper reviewed the occurrence of transgenic rice gene flow and its potential ecological consequences.

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